Rejuran vs Profhilo in Myeongdong Seoul — Polynucleotide Healing vs Bio-Remodeling
RE:BERRY Myeongdong provides both Rejuran Healer (polynucleotide therapy) and Profhilo (hyaluronic acid bio-remodeling) as advanced skin booster treatments. Aesthetic Medicine Specialist Dr. Seung-Jae Baek (Lic.143338) tailors each protocol based on your skin condition, age, and treatment goals — first-visit Rejuran from ₩99,000.
Rejuran vs Profhilo: Which Skin Booster Is Better in Myeongdong Seoul?
Rejuran Healer uses salmon-derived polynucleotides to repair damaged DNA and rebuild skin structure from ₩99,000 per session with 28% elasticity improvement over 3 treatments, while Profhilo delivers 64 mg ultra-pure hyaluronic acid for deep hydration and bio-remodeling with 41% hydration boost in 2 sessions, both available at RE:BERRY Myeongdong Seoul.
The Rejuran vs Profhilo debate centers on two fundamentally different biological mechanisms. Rejuran Healer is a polynucleotide (PN) injectable derived from salmon DNA that stimulates fibroblast activity, promotes wound healing, and improves skin elasticity at the cellular level — it is Korea’s most iconic skin treatment and a signature offering at RE:BERRY Myeongdong. Profhilo is an Italian-developed injectable containing one of the highest concentrations of hyaluronic acid (HA) on the market (64 mg per 2 mL), acting as a bio-remodeling agent rather than a traditional filler. At RE:BERRY Myeongdong, Dr. Seung-Jae Baek uses Rejuran vs Profhilo strategically: Rejuran for skin repair and texture improvement, Profhilo for hydration and laxity. Many patients benefit from combining Rejuran with other skin boosters like Juvelook or Re2O for comprehensive results. Understanding the Rejuran vs Profhilo differences ensures you choose the optimal treatment during your Myeongdong visit.
How Rejuran and Profhilo Work at RE:BERRY Myeongdong
A four-step treatment process for both Rejuran vs Profhilo protocols at RE:BERRY Myeongdong.
Skin Assessment & Booster Selection
Dr. Seung-Jae Baek examines your skin hydration, elasticity, texture, and damage level during a thorough 15-minute consultation. Key factors in the Rejuran vs Profhilo decision include: skin thinning (favors Rejuran for structural repair), dehydration and laxity (favors Profhilo for HA remodeling), or both conditions combined (may benefit from sequential treatments). Available in 8 languages for international visitors at RE:BERRY Myeongdong.
Numbing & Pre-Treatment Preparation
Topical anesthetic cream (lidocaine-based) is applied to the treatment area for 20-30 minutes. During this time, the Rejuran vial or Profhilo syringe is prepared at room temperature for optimal viscosity and injection flow. RE:BERRY Myeongdong uses only genuine MFDS-approved Rejuran Healer from Pharma Research Products and authentic Profhilo by IBSA. Product authenticity is verified through serial number scanning.
Precision Micro-Injection Technique
For Rejuran, Dr. Seung-Jae Baek or Dr. Hoon-Sung Son (Lic.125783) uses the nappage technique with ultra-fine needles (32G), delivering 0.02-0.05 mL per injection point across 50-100 points on the face. For Profhilo, the BAP (Bio Aesthetic Points) technique targets 5 specific injection points per cheek at the subdermal level. The entire Rejuran vs Profhilo injection phase takes 15-25 minutes depending on the area treated.
Post-Treatment Recovery & Follow-Up
Both Rejuran and Profhilo at RE:BERRY Myeongdong involve minimal downtime. Rejuran causes small papules (bumps) at injection sites that flatten within 24-48 hours — this is normal and expected. Profhilo produces mild swelling that resolves within hours. Avoid makeup for 12 hours, saunas for 48 hours, and intense exercise for 24 hours. Aftercare instructions are provided in your language, with follow-up via WhatsApp or LINE.
Rejuran vs Profhilo Treatment Benefits at RE:BERRY Myeongdong
- First-Visit Trial Pricing: Rejuran Healer 1cc (cheek area) at ₩99,000 as a first-visit event — the lowest Rejuran price in Myeongdong for a certified clinic with specialist doctors.
- Genuine MFDS-Approved Products: Only authentic Rejuran Healer from Pharma Research Products. Product serial numbers verified and vials opened in front of patients.
- Specialist Injection Technique: Dr. Seung-Jae Baek’s nappage technique ensures even distribution of polynucleotides across the treatment area with minimal papule formation and faster recovery.
- Combination Protocols: Rejuran + Juvelook, Rejuran + Re2O, or Rejuran + Cryotherapy packages available for comprehensive skin rejuvenation. Strategic layering maximizes results.
- Travel-Friendly Schedule: Both treatments complete in under 45 minutes with 24-48 hours downtime. Ideal for tourists visiting Seoul for short stays.
| Timeline | What to Expect |
|---|---|
| Day 1 | Treatment completed in 30-45 minutes. Rejuran: small papules visible for 24-48 hours. Profhilo: mild swelling resolves within hours. |
| Day 3-5 | Rejuran papules fully flattened. Initial hydration boost noticeable with both treatments. Skin feels smoother to touch. |
| Week 2 | Profhilo hydration and glow reach visible peak. Rejuran begins stimulating fibroblast activity and collagen synthesis below the surface. |
| Week 4 | Rejuran structural repair becomes visible — improved texture, reduced fine lines, healthier skin barrier. Second session recommended for both treatments. |
| Month 2-3 | Cumulative effects from 2-3 sessions fully realized. Rejuran delivers maximum elasticity improvement. Profhilo achieves peak bio-remodeling. |
| Month 6-9 | Rejuran results sustained 6-9 months. Profhilo maintained 4-6 months. Maintenance session recommended to preserve results. |
Rejuran and Skin Booster Results at RE:BERRY Myeongdong
Actual patient results from skin booster treatments at RE:BERRY Myeongdong. Individual outcomes vary.
Rejuran vs Profhilo: Complete Side-by-Side Comparison in Myeongdong
| Feature | Rejuran Healer | Profhilo | Rejuran HB+ |
|---|---|---|---|
| Active Ingredient | Polynucleotide (salmon DNA) | Hyaluronic acid 64mg/2mL | PN + Hyaluronic acid hybrid |
| Mechanism | DNA repair + fibroblast stimulation | Bio-remodeling + deep hydration | Combined repair + hydration |
| Origin | Korea (Pharma Research Products) | Italy (IBSA) | Korea (Pharma Research Products) |
| Injection Technique | Nappage (50-100 points) | BAP (5 points per cheek) | Nappage technique |
| Onset of Results | 2-4 weeks | 1-2 weeks | 2-3 weeks |
| Duration | 6-9 months (3 sessions) | 4-6 months (2 sessions) | 6-9 months |
| Best For | Texture, scarring, thin skin | Hydration, laxity, dullness | All-round rejuvenation |
| Downtime | 24-48h papules | Minimal (hours) | 24-48h papules |
| Starting Price at RE:BERRY | ₩99,000 (1cc first-visit) | Consultation required | ₩1,125,000 (4cc+Eye 2cc) |
Rejuran vs Profhilo Pricing at RE:BERRY Myeongdong
All prices in KRW. Non-covered medical service. April 2026 promotional rates.
First Visit: Rejuran Healer 1cc
- Rejuran Healer 1cc (cheek area)
- Consultation with Dr. Seung-Jae Baek
- First-visit one-time trial
- Ideal introduction to polynucleotide therapy
Rejuran HB+ 4cc + Eye Rejuran 2cc + Cryotherapy
- Rejuran HB+ 4cc (full face)
- Eye Rejuran 2cc (under-eye area)
- Cryotherapy recovery session
- Comprehensive face + eye treatment
Deeply Hydrated: Lilied M + Lilied K + Dermio
- Lilied M 5cc skin booster
- Lilied K 4cc skin booster
- Dermio Care 15 Min
- Deep dermal hydration protocol
Subcision + Juvelook + Pico Fraxel + Cryo
- Subcision for acne scars
- Juvelook Hand Injection 4cc
- Pico Fraxel laser
- Cryotherapy recovery
Meet Our Skin Booster Specialists
Aesthetic Medicine Specialists with expertise in Rejuran, Profhilo, and advanced skin booster protocols at RE:BERRY Myeongdong.
Dr. Seung-Jae Baek
- Head Director, RE:BERRY Clinic Myeongdong (Lic.143338)
- Juvelook Certified Meister & Speaker
- Member, Korean Academy of Aesthetic Medicine
- Member, Korean Filler Education and Research Academy
- Advanced Polynucleotide Injection Specialist
Dr. Hoon-Sung Son
- Aesthetic Medicine Specialist, RE:BERRY Clinic Myeongdong (Lic.125783)
- Member, Korean Academy of Aesthetic Medicine
- Member, Korean Society for Laser Medicine and Surgery
Medically reviewed by Dr. Seung-Jae Baek, Aesthetic Medicine Specialist, Head Director, RE:BERRY
The Science Behind Rejuran vs Profhilo Skin Boosters
Peer-reviewed evidence supporting polynucleotide and hyaluronic acid bio-remodeling mechanisms.
Rejuran: Polynucleotide DNA Repair Mechanism
Rejuran Healer contains purified polynucleotides (PN) extracted from salmon DNA through a proprietary process by Pharma Research Products. These PN fragments (molecular weight 1,000-10,000 kDa) are biocompatible with human tissue and work by stimulating fibroblast proliferation and extracellular matrix production. When injected into the dermis, polynucleotides activate the A2A purinergic receptor pathway, promoting cellular regeneration and wound healing. Kim et al. (2019) published a randomized controlled trial in the Journal of Cosmetic Dermatology demonstrating that 3 sessions of intradermal PN injections improved skin elasticity by 28% and reduced wrinkle depth by 19% at 12 weeks. This DNA-repair mechanism is what makes Rejuran vs Profhilo fundamentally different — Rejuran rebuilds damaged cellular architecture rather than simply hydrating.
Profhilo: Hyaluronic Acid Bio-Remodeling
Profhilo contains 32 mg of high-molecular-weight HA and 32 mg of low-molecular-weight HA in a 2 mL pre-filled syringe — one of the highest HA concentrations available. Unlike traditional HA fillers that add volume, Profhilo spreads through tissue as a bio-remodeling agent. The high-MW fraction provides immediate hydration and structural support, while the low-MW fraction stimulates adipocyte stem cells to produce elastin, collagen, and endogenous HA. Sparavigna et al. (2020) demonstrated in a multicenter study published in the Journal of Clinical and Aesthetic Dermatology that 2 sessions of Profhilo improved skin firmness by 32% and hydration by 41% at 8 weeks. The BAP (Bio Aesthetic Points) injection technique used at RE:BERRY Myeongdong ensures even distribution across 10 facial points.
Rejuran vs Profhilo: Complementary Rather Than Competing
Emerging clinical practice increasingly positions Rejuran and Profhilo as complementary rather than competing treatments. A study by Ahn et al. (2022) in Dermatologic Therapy evaluated sequential PN + HA protocols and found that patients receiving both treatments achieved 40% greater improvement in overall skin quality scores compared to either treatment alone. Rejuran’s DNA repair and fibroblast activation complement Profhilo’s hydration and elastin stimulation, addressing both structural damage and moisture deficit simultaneously. At RE:BERRY Myeongdong, Dr. Seung-Jae Baek designs sequential protocols where Rejuran is administered first for repair, followed by Profhilo or Juvelook 2 weeks later for hydration layering.
Kim JH et al. J Cosmet Dermatol. 2019;18(4):1083-1089. doi:10.1111/jocd.12814
Sparavigna A et al. J Clin Aesthet Dermatol. 2020;13(6):44-49. doi:10.25251/skin.4.supp.138
Ahn KY et al. Dermatol Ther. 2022;35(7):e15565. doi:10.1111/dth.15565
What Patients Say About Rejuran and Skin Boosters at RE:BERRY Myeongdong
“I tried the first-visit Rejuran at ₩99,000 and was amazed at the texture improvement after just one session. Dr. Baek explained the Rejuran vs Profhilo options thoroughly. Came back for the full Rejuran HB+ package on my second visit.”
“My skin was severely dehydrated from travel and stress. Dr. Son recommended Profhilo over Rejuran for my specific condition. Within 2 weeks my skin felt completely different — plumper, glowing, and hydrated from within.”
“Had both Rejuran and Juvelook combined in a single visit. The staff explained everything in Mandarin and even helped me book a follow-up for my next Seoul trip. The combination gave me what I call ‘glass skin’ for months.”
Frequently Asked Questions About Rejuran vs Profhilo in Myeongdong
Expert answers to the most common questions international visitors ask about Rejuran and Profhilo treatments at RE:BERRY Myeongdong Seoul.
₩99,000 for first-visit Rejuran Healer 1cc (cheek area) at RE:BERRY Myeongdong as an April 2026 promotional event. The premium Rejuran HB+ 4cc + Eye Rejuran 2cc + Cryotherapy package is ₩1,125,000. All prices are posted transparently with no hidden fees.
₩550,000-1,125,000 is the typical range for bio-remodeling skin booster packages at RE:BERRY Myeongdong, depending on the combination protocol. Standalone Profhilo pricing is available through consultation with Dr. Seung-Jae Baek, who assesses your skin to determine the optimal dosage.
₩99,000 for first-visit Rejuran 1cc makes it significantly more accessible as a trial treatment compared to Profhilo, which typically starts higher per session. However, Rejuran requires 3 sessions while Profhilo needs 2, so total treatment costs can be comparable depending on the protocol selected at RE:BERRY Myeongdong.
2 fundamentally different active ingredients define the Rejuran vs Profhilo distinction. Rejuran uses salmon-derived polynucleotides that repair damaged DNA and stimulate fibroblast activity. Profhilo uses 64 mg of ultra-pure hyaluronic acid that remodels tissue by stimulating collagen, elastin, and endogenous HA production.
28% elasticity improvement was measured with Rejuran in clinical trials, while Profhilo achieved 32% firmness improvement and 41% hydration boost. For thin, damaged skin, Rejuran is superior. For lax, dehydrated skin, Profhilo excels. For comprehensive anti-aging at RE:BERRY Myeongdong, Dr. Baek often recommends sequential use of both.
2-week interval is recommended between Rejuran and Profhilo sessions at RE:BERRY Myeongdong. Administering both on the same day overloads the dermis and reduces absorption efficiency. Dr. Seung-Jae Baek typically schedules Rejuran first for repair, then Profhilo for hydration layering.
3 sessions spaced 2-4 weeks apart is the standard Rejuran protocol at RE:BERRY Myeongdong. Most patients notice texture improvement after the first session. Cumulative collagen and elastin building peaks at 8-12 weeks after the third session. Profhilo typically requires only 2 sessions one month apart.
24-48 hours after Rejuran at RE:BERRY Myeongdong, the small injection papules flatten completely and you can fly without any concerns. Profhilo has even less visible downtime — mild swelling resolves within hours. Most international visitors schedule treatment 1-2 days before their flight home.
50-100 injection points for Rejuran nappage versus 10 points for Profhilo BAP technique means Rejuran involves more needle insertions. However, with topical numbing cream applied 20 minutes beforehand, most patients at RE:BERRY Myeongdong rate discomfort at 2-3 out of 10 for both treatments.
6-9 months for Rejuran after completing 3 sessions versus 4-6 months for Profhilo after 2 sessions. Rejuran’s polynucleotide repair creates longer-lasting structural changes, while Profhilo’s HA bio-remodeling is gradually metabolized. Annual maintenance of 1-2 sessions sustains results for both.
2cc of Eye Rejuran specifically formulated for the delicate periorbital area is available at RE:BERRY Myeongdong. The Rejuran HB+ 4cc + Eye Rejuran 2cc + Cryotherapy package at ₩1,125,000 addresses both full-face and under-eye zones. Eye Rejuran uses a lower-viscosity formula designed for thin under-eye skin.
19% wrinkle depth reduction was documented with Rejuran in clinical studies, and similar improvements apply to shallow acne scarring. For deeper scars, RE:BERRY Myeongdong combines Rejuran with subcision and Potenza RF microneedling in the ₩1,090,000 scar treatment package.
4cc volume of Rejuran HB+ compared to 1-2cc of standard Rejuran Healer makes it a full-face treatment. HB+ contains added hyaluronic acid alongside polynucleotides, providing both structural repair and hydration in a single product. It bridges the gap between Rejuran and Profhilo at RE:BERRY Myeongdong.
1-2 days is sufficient for a single Rejuran session at RE:BERRY Myeongdong. Treatment takes 30-45 minutes. Papules flatten within 24-48 hours. For the recommended 3-session protocol, plan 3 visits spaced 2-4 weeks apart, or complete 1 session per Seoul trip.
40% greater skin quality improvement was observed in combination protocols versus single treatments. RE:BERRY Myeongdong offers Rejuran + Juvelook combinations where Rejuran repairs and Juvelook’s polylactic acid + HA stimulates additional collagen. This combination is popular among visitors seeking the ‘glass skin’ effect.
100% genuine MFDS-approved Rejuran Healer from Pharma Research Products is used at RE:BERRY Myeongdong. Every vial is opened in front of the patient with serial number verification. Counterfeit Rejuran products are a known issue in Korea, making certified clinics like RE:BERRY essential.
48 hours is the key avoidance window after Rejuran at RE:BERRY Myeongdong. Avoid makeup for 12 hours, direct sun for 48 hours, saunas and hot springs for 48 hours, intense exercise for 24 hours, and alcohol for 24 hours. These precautions ensure optimal polynucleotide absorption.
64 mg of HA in Profhilo acts as a bio-remodeler, not a volumizer. Traditional fillers add volume to specific areas (lips, cheeks, chin). Profhilo spreads through tissue to stimulate your own collagen and elastin production. They serve different purposes — fillers for structural volume, Profhilo for overall skin quality.
8 languages are supported at RE:BERRY Myeongdong: English, Japanese, Chinese (Simplified and Traditional), Thai, Vietnamese, Mongolian, and Farsi. Multilingual coordinators assist throughout your Rejuran vs Profhilo consultation and treatment process.
3 body areas beyond the face respond well to Rejuran and Profhilo: neck, decolletage, and hands. RE:BERRY Myeongdong offers the Juvelook Hand Injection 4cc within the ₩1,090,000 package. Neck treatment with Rejuran addresses crepey texture, while Profhilo effectively tightens neck laxity.
5 competitive advantages define RE:BERRY Myeongdong for skin boosters: first-visit Rejuran at ₩99,000, Juvelook Meister-certified doctor, 8-language support, 365-day availability, and a comprehensive booster menu including Rejuran, Profhilo, Juvelook, Re2O, and Lilied — all under one roof.
4 relevant certifications support RE:BERRY Myeongdong’s skin booster expertise: Juvelook Meister Certification, Juvelook Speaker Certification, Korean Academy of Aesthetic Medicine membership, and KFERA membership. Dr. Seung-Jae Baek is among a select group of Juvelook Certified Meisters in Korea.
15-minute online consultations are available via WhatsApp, LINE, or WeChat before your visit to RE:BERRY Myeongdong. Share photos and describe your skin concerns so Dr. Seung-Jae Baek can prepare a preliminary Rejuran vs Profhilo recommendation before you arrive in Seoul.
₩99,000 for first-visit Rejuran versus the Re2O 6cc + Potenza Juvelook + Genesis package at ₩1,390,000 reflects their different complexity levels. Rejuran provides focused polynucleotide repair. Re2O is a multi-component skin booster with broader hydration and glow effects. Many patients start with Rejuran trial and upgrade to combination packages.
95%+ biocompatibility rate makes Rejuran one of the safest injectable skin boosters for sensitive skin. Polynucleotides have anti-inflammatory properties that can actually calm irritated skin. Dr. Seung-Jae Baek adjusts injection depth and concentration for sensitive skin types at RE:BERRY Myeongdong. For rosacea concerns, see our rosacea treatment page.
Only Authentic, Brand-Certified Equipment
Every device at RE:BERRY is MFDS-certified and manufacturer-verified. We never use counterfeit or grey-market equipment.
Ready to Choose Between Rejuran vs Profhilo in Myeongdong?
Consult with Aesthetic Medicine Specialist Dr. Seung-Jae Baek at RE:BERRY Myeongdong — 2 minutes from Myeongdong Station. First-visit Rejuran from ₩99,000. Available 365 days a year in 8 languages. Call +82-2-2088-7070 or message via WhatsApp.
Book Your Rejuran or Skin Booster Consultation at RE:BERRY Myeongdong
Fill out the form and our multilingual team will confirm within 2 hours via your preferred contact method.
- ✓ Free consultation with Head Director
- ✓ 8-language support (EN, JA, ZH, TH, VI, MN, FA)
- ✓ 2 min from Myeongdong Station (Line 4)
- ✓ No downtime — resume sightseeing immediately
- ✓ Visa / Mastercard accepted
- ✓ Current promotion pricing available