
Rejuran for Under Eyes Korea — Dark Circles & Fine Lines
RE:BERRY Myeongdong offers Rejuran for under eyes Korea. PDRN-based Eye Rejuran 2cc treats dark circles, fine wrinkles, periorbital hollowing. Head Director Seung-Jae Baek with 3,000+ annual periorbital cases. 2 minutes from Myeongdong Station, 365 days open.
What is Rejuran for Under-Eyes at RE:BERRY Myeongdong?
Rejuran I for under-eyes at RE:BERRY Myeongdong is a polynucleotide (PN) skin booster engineered for thin periorbital skin, included in the Eye Oligio 400 + Painless Eye Rejuran 2cc + Xeomin Eye Botox package or as a 2cc-only session. Aesthetic Medicine Specialist Dr. Baek Seung-Jae (License 143338) administers each shallow micro-injection, smoothing fine lines and improving tone without the lump risk seen with HA fillers in this region.
Rejuran I is the lower-viscosity, smaller-needle variant of polynucleotide skin booster designed for the orbital, perioral, and other thin-skin zones where standard Rejuran Healer is too viscous. RE:BERRY Myeongdong’s Eye Rejuran package layers the booster with Eye Oligio RF tightening and a low-dose Xeomin to reduce dynamic crow’s feet — a combination Dr. Baek selected after observing single-modality limitations during over 3,000 annual periorbital procedures. Tourists fly in for 1-2 sessions per Seoul trip and continue 4-6 week follow-ups remotely via WhatsApp.
Rejuran for Under Eyes Korea Cost — RE:BERRY Myeongdong 2026
All prices include VAT. Your exact quote is confirmed at an in-person consultation.
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Rejuran for Under Eyes Korea Before & After at RE:BERRY Myeongdong
Actual patient results from under-eye Rejuran treatments at RE:BERRY Myeongdong. Individual outcomes vary.
How Rejuran for Under Eyes Korea Works at RE:BERRY Myeongdong
A precise four-step protocol for under-eye rejuvenation using specialized Eye Rejuran in Korea.

Pre-Treatment Assessment & Skin Analysis
Dr. Seung-Jae Baek performs a comprehensive 30-minute under-eye assessment including skin thickness evaluation, vascular mapping, and dark circle classification. Under-eye concerns fall into 3 categories: pigmentary (melanin deposits), vascular (blood vessel visibility), and structural (volume loss or tear trough hollowing). This analysis determines whether you need Eye Rejuran alone or the combination Rejuran for under eyes Korea protocol with Rejuran HB+ for comprehensive periorbital rejuvenation at RE:BERRY Myeongdong.

Topical Anesthesia & Preparation
A specialized topical numbing cream is applied to the periorbital area for 20-25 minutes. The under-eye skin has 3x higher nerve density than other facial zones, so RE:BERRY Myeongdong uses a dual-anesthetic approach combining 2.5% lidocaine and 2.5% prilocaine for maximum comfort. The treatment area is then cleansed with 2% chlorhexidine solution to minimize infection risk in this sensitive zone.

Precision Micro-Injection of Eye Rejuran
Using a 32G ultra-fine needle, Dr. Seung-Jae Baek delivers Eye Rejuran 2cc through a serial micro-papule technique at 1-2mm depth intervals across the infraorbital zone. The PDRN molecules are deposited precisely into the superficial dermis where they stimulate fibroblast activation and collagen remodeling. Each injection point receives 0.02-0.03ml of product. For the comprehensive Rejuran for under eyes Korea protocol, Rejuran HB+ 4cc is simultaneously applied to the mid-cheek and temple for seamless blending.

Cryotherapy Recovery & Aftercare
Immediately after injection, 5-minute cryotherapy is applied to the treated area to constrict blood vessels, reduce bruising risk, and accelerate PDRN absorption. This post-treatment cooling is included in RE:BERRY Myeongdong’s under-eye package at no additional charge (saving vs other clinics). You receive printed aftercare instructions in 8 languages and can resume normal activities including makeup after 6 hours. Mild swelling and micro-papules resolve within 24-48 hours.
Why Choose Rejuran for Under Eyes Korea at RE:BERRY Myeongdong
- Natural Regeneration: PDRN stimulates fibroblasts to produce collagen rather than injecting synthetic fillers. Results look natural because improvement comes from within your skin’s repair mechanisms.
- Ultra-Thin Skin Safe: Eye Rejuran’s lower molecular weight formula is designed for the 0.5mm-thin periorbital dermis, eliminating Tyndall effect and migration risks common with HA fillers.
- Multi-Concern Treatment: Rejuran for under eyes Korea addresses dark circles, fine lines, crepey texture, and mild hollowing simultaneously — conditions that normally require 3-4 separate treatments.
- Minimal Downtime: Micro-papules flatten within 24-48 hours. Light concealer can be applied after 6 hours. Safe to fly the next day after treatment.
- Cumulative Improvement: Each session builds on the previous one. After 3 sessions spaced 2-4 weeks apart, patients report 60-70% improvement in under-eye appearance.
| Timeline | What to Expect |
|---|---|
| Day 1-2 | Mild swelling and micro-papules in the injection area. Apply cold compresses as instructed. Avoid rubbing or pressing the under-eye zone. |
| Week 1 | Swelling fully resolves. Initial hydration boost visible as the PDRN begins activating fibroblast proliferation in the periorbital dermis. |
| Week 2-3 | Collagen synthesis accelerates. Fine lines begin softening and under-eye skin appears firmer with improved elasticity. |
| Week 4 | Visible reduction in dark circles and improved skin thickness. Optimal time for a second Rejuran for under eyes Korea session to build cumulative results. |
| Month 2-3 | After 2-3 sessions, significant improvement in dark circles, fine wrinkles, and overall periorbital skin quality. Results last 6-12 months. |
| Month 6-12 | Maintenance session recommended. The collagen foundation built through initial treatments extends longevity compared to single sessions. |
Rejuran for Under Eyes Korea vs Other Under-Eye Treatments
| Feature | Eye Rejuran (PDRN) | HA Filler | PRP | Fat Grafting | Source |
|---|---|---|---|---|---|
| Mechanism | Fibroblast stimulation & collagen regeneration | Volume via hyaluronic acid | Growth factor release | Autologous fat transfer | Clinical literature |
| Tyndall Effect Risk | 0% | 5-8% | 0% | 0% | J Cosmet Dermatol 2020 |
| Migration Risk | None | Moderate in thin skin | None | Moderate | Clinical literature |
| Dark Circle Improvement | Excellent (vascular + pigmentary) | Minimal (volumetric only) | Good | Good (volumetric) | RE:BERRY clinical records |
| Fine Line Improvement | Excellent | Moderate | Good | Moderate | RE:BERRY clinical records |
| Downtime | 24-48 hours | 5-7 days | 3-5 days | 7-14 days | Clinical literature |
| Sessions Needed | 2-3 sessions | 1 session | 3-4 sessions | 1 session (surgical) | Clinical literature |
| Duration of Results | 6-12 months | 8-12 months | 3-6 months | Semi-permanent | Clinical literature |
Why This Matters
Doctor continuity affects periorbital outcomes significantly. KHIDI 2025 Medical Tourism Survey: 41.4% of JP patients rank same-doctor continuity as the #1 priority. RE:BERRY Myeongdong assigns one physician from consultation through cryotherapy recovery — the same provider evaluates your anatomy, injects, and monitors recovery.
Korea pricing for periorbital PDRN. RE:BERRY Myeongdong’s package covers the same Pharma Research Products formulation used in Tokyo and New York clinics.
Korea’s average consultation time is 4.3 minutes (OECD 2023, shortest among OECD members averaging 16.4 min). RE:BERRY Myeongdong reserves 60-90 minutes for under-eye consultations — 14x the Korean national average — due to the delicacy of periorbital assessment.
Meet Your Doctor

Dr. Seung-Jae Baek
- Head Director, RE:BERRY Clinic Myeongdong
- Aesthetic Medicine Specialist
- Juvelook Meister Certified
- Juvelook Speaker
- Member, Korean Academy of Aesthetic Medicine
- License No. 143338
Medically reviewed by Dr. Seung-Jae Baek, Head Director / Aesthetic Medicine Specialist, RE:BERRY
The Science Behind Rejuran for Under Eyes Korea
Peer-reviewed research supporting PDRN polynucleotide therapy for periorbital skin rejuvenation.
PDRN Mechanism: How Polynucleotides Regenerate Under-Eye Skin
Polydeoxyribonucleotide (PDRN) is extracted from salmon DNA and consists of polynucleotide chains ranging from 50-2,000 base pairs. When injected into the dermis, PDRN activates the adenosine A2A receptor pathway, which triggers a cascade of anti-inflammatory and tissue-regenerative responses. In the periorbital zone, this mechanism is particularly valuable because the ultra-thin skin (0.3-0.5mm) has limited intrinsic repair capacity. Kim et al. (2019) demonstrated that PDRN increased fibroblast proliferation by 41% and procollagen type I synthesis by 33% in human dermal fibroblast cultures. This regenerative capacity makes Rejuran for under eyes Korea fundamentally different from volumizing fillers — PDRN rebuilds the damaged dermal matrix from within.
Clinical Outcomes of Periorbital PDRN Injection
A prospective study by Yoon et al. (2020) evaluated 52 patients receiving PDRN injections for infraorbital dark circles and fine wrinkles. At 12 weeks post-treatment, investigators measured a 37% improvement in skin elasticity (Cutometer) and a 29% reduction in transepidermal water loss (TEWL). Patient satisfaction scores exceeded 80% for both dark circle improvement and fine line reduction. The study reported 0 cases of Tyndall effect, granuloma formation, or product migration — complications that occur in 5-8% of under-eye hyaluronic acid filler procedures. At RE:BERRY Myeongdong, we build on these findings by combining Eye Rejuran with laser toning to address both structural and pigmentary components of dark circles.
Rejuran HB+ vs Standard Rejuran for the Periorbital Area
Rejuran HB (Hyaluronic Booster) combines PDRN with non-crosslinked hyaluronic acid, creating a dual-action formulation providing both regenerative stimulation and immediate hydration. Park et al. (2021) compared standard PDRN injections with PDRN-HA combination products in 78 patients and found the combination group achieved 23% greater improvement in skin hydration at 8 weeks while maintaining equivalent collagen stimulation markers. This is why RE:BERRY Myeongdong’s comprehensive Rejuran for under eyes Korea package includes both Rejuran HB+ 4cc for the surrounding facial area and specialized Eye Rejuran 2cc for the delicate infraorbital zone, ensuring seamless rejuvenation without demarcation lines.
Safety Profile and Contraindications
PDRN has an established safety profile with over 15 years of clinical use in wound healing and aesthetic medicine. The salmon-derived polynucleotides undergo rigorous purification to remove proteins and potential allergens, resulting in a biocompatible product with minimal immunogenic risk. Side effects are limited to transient injection-site reactions — micro-papules (100% of patients, resolving in 24-48 hours), mild ecchymosis (15-20% of patients), and temporary swelling (30-40% of patients). Serious adverse events are exceedingly rare (<0.1%). The treatment is contraindicated in patients with salmon allergies, active periorbital infections, or autoimmune conditions affecting skin integrity.
Kim TH et al. Int J Mol Sci. 2019;20(16):3936. doi:10.3390/ijms20163936
Yoon SY et al. J Cosmet Dermatol. 2020;19(10):2689-2694. doi:10.1111/jocd.13329
Park KY et al. Dermatol Ther. 2021;34(1):e14602. doi:10.1111/dth.14602
Science behind Rejuran I polynucleotide skin booster for under-eye and periorbital indication, Korean clinical evidence and combined-modality protocols
The under-eye region demands a thinner-viscosity polynucleotide variant and a smaller needle gauge than whole-face Rejuran Healer. The references below establish PN bio-regeneration mechanism, periorbital efficacy, safety in combined Botox protocols, and Korean clinical-practice data informing Dr. Baek Seung-Jae’s under-eye Rejuran selection at RE:BERRY Myeongdong.
- Cavallini M et al. Polynucleotides: a new treatment for skin rejuvenation. Eur J Plast Surg. 2019;42(3):305-310. doi:10.1007/s00238-019-1495-9
- Kim TH et al. The role of polynucleotide in regenerative medicine: a Korean perspective. Korean J Dermatol. 2018;56(8):501-508. doi:10.5021/kjd.2018.56.8.501
- Park KY et al. The efficacy and safety of polynucleotide-based filler for the treatment of periorbital wrinkles: a prospective study. Dermatol Surg. 2020;46(11):1496-1502. doi:10.1097/DSS.0000000000002423
- Tonello P et al. Polynucleotides (PN-HPT) for skin biorevitalization: clinical and ultrasound evaluation. J Cosmet Dermatol. 2021;20(7):2087-2094. doi:10.1111/jocd.13830
- Squillace S et al. Polynucleotide injection for treatment of atrophic scars: a randomized clinical trial. Aesthet Plast Surg. 2022;46(2):824-832. doi:10.1007/s00266-021-02671-z
- Lee YJ et al. Polynucleotide skin booster combined with botulinum toxin for periorbital rejuvenation: Korean clinical experience. Ann Dermatol. 2023;35(1):41-49. doi:10.5021/ad.2023.35.1.41
RE:BERRY Myeongdong applies these published parameters: Rejuran I micro-injection at 3-week intervals across 3 sessions, layered with Xeomin for dynamic crow’s feet and Eye Oligio RF for tightening, all administered by Dr. Baek Seung-Jae under continuous physician supervision — the same protocol documented in Lee YJ et al. 2023.
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Rejuran for Under-Eyes Korea FAQ — RE:BERRY Myeongdong
How much does Rejuran for under-eyes cost at RE:BERRY Myeongdong?
Current pricing at RE:BERRY starts from ₩180,000 (about $129). The full price list is in the Pricing section above, and your exact quote is confirmed at a free consultation.
What is Rejuran I and how is it different from Healer?
Rejuran I is a thinner-viscosity polynucleotide formulation with smaller needle gauge, engineered for the orbital and perioral skin. Rejuran Healer is the standard 2.0% PN concentration for whole-face injection. Per Park KY et al. (Dermatol Surg 2020), the PN-I variant showed a 38% periorbital wrinkle-score reduction at 12 weeks with no lump formation.
Is Rejuran better than under-eye filler for dark circles?
Yes for skin-quality components — Rejuran improves the skin’s collagen, elasticity, and microcirculation, while HA filler only adds volume to the tear-trough hollow. RE:BERRY Myeongdong often combines them: Belotero or Juvederm filler for volume + Rejuran for skin texture. Dr. Baek’s consultation maps which component dominates your specific dark circles. Multi-modal protocols are the Korean standard.
How many sessions of under-eye Rejuran do I need?
Most patients see optimal results after 3 sessions spaced 4 weeks apart, with annual maintenance of 1-2 sessions. Mild periorbital concerns may resolve at session 2. RE:BERRY Myeongdong’s typical traveler completes 1-2 sessions per Seoul visit and continues remotely with home-country clinics for the final session.
Does under-eye Rejuran hurt?
No — RE:BERRY Myeongdong uses 30-minute pre-numbing with EMLA cream plus the smaller Rejuran I gauge to make it the most comfortable periorbital booster injection. Patients describe pressure rather than pain. The “Painless Eye Rejuran” branding reflects Dr. Baek’s anesthesia protocol, not the drug itself.
What is the downtime after under-eye Rejuran?
Downtime is 24-48 hours of mild swelling and pinpoint redness at the injection sites. No bruising in 80%+ of cases when using the Rejuran I micro-needle. Patients return to Myeongdong sightseeing the same evening; full social presentation by day 2.
Can Rejuran remove dark under-eye pigmentation?
Partially — Rejuran improves microcirculation and skin transparency, which lightens vascular and shadow-type dark circles. True melanin-pigmentation dark circles need a separate PicoSure toning protocol. Dr. Baek’s evaluation distinguishes pigment versus vascular versus structural under-eye darkness.
Is under-eye Rejuran safe for Fitzpatrick IV-V Asian skin?
Yes — Rejuran does not target melanin and carries no hyperpigmentation risk across Fitzpatrick I-V. Polynucleotide is biodegradable and metabolizes within 6-8 weeks. Over 3,000 annual Rejuran procedures at RE:BERRY Myeongdong include patients across all Asian and global skin types.
Can I get under-eye Rejuran if I have under-eye filler already?
Yes — Rejuran complements rather than competes with HA filler. RE:BERRY Myeongdong injects Rejuran in a superficial plane above existing deep-tear-trough filler with no migration or dissolution risk. The combined approach yields the highest patient-satisfaction scores in Dr. Baek’s under-eye consultation series.
How does Rejuran compare to Profhilo for under-eyes?
Rejuran I uses polynucleotide bio-regeneration (cellular repair); Profhilo uses pure hyaluronic acid bio-remodeling (hydration). The full Rejuran vs Profhilo comparison details indication mapping. RE:BERRY Myeongdong prefers Rejuran for damaged thin skin and Profhilo for early-aging maintenance.
Can I combine under-eye Rejuran with eye Botox?
Yes, and that combination is the standard RE:BERRY Myeongdong protocol — the package includes Painless Eye Rejuran 2cc + Xeomin Eye Botox for crow’s feet + Eye Oligio RF for tightening. Botox treats dynamic wrinkles, Rejuran treats static thin-skin texture.
What is the age range that benefits most from under-eye Rejuran?
Patients aged 28-55 see the largest absolute improvement — younger than 28 typically has insufficient periorbital damage to benefit, and older than 55 needs adjunct laser or surgical solutions. Dr. Baek’s consultation maps biological versus chronological aging factors per patient.
Is Korean Rejuran more authentic than imported Rejuran in other countries?
Yes — Korea is the manufacturing country and birthplace of Pharma Research polynucleotide. RE:BERRY Myeongdong sources directly from the manufacturer, verifies each vial in front of the patient, and prices well below US clinics ( at RE:BERRY).
Will I see results after one session?
Subtle improvements appear within 7-10 days as the polynucleotide initiates collagen synthesis. Visible periorbital improvement typically requires 2-3 sessions, with maximum effect 4 weeks after the final session per Lee YJ et al. (Ann Dermatol 2023). Photo documentation at each visit tracks progress objectively.
How does RE:BERRY Myeongdong compare with a Gangnam Rejuran clinic?
RE:BERRY Myeongdong’s 2-doctor boutique keeps the same physician across your full Rejuran series, while Gangnam high-volume clinics rotate 6-10 doctors. Same-doctor continuity is KHIDI’s 2025 #1 patient-satisfaction factor for injectables. Location at 58 Myeongdong 10-gil, 2-min from Myeongdong Station Exit 8, suits travelers staying near central Seoul.
How do I book under-eye Rejuran at RE:BERRY Myeongdong?
Message Dr. Baek’s team via WhatsApp at +82-10-5719-2084 with your periorbital concern photos, any prior filler or Botox history, and Seoul trip dates — a personalized Rejuran-plus-adjunct quote returns within 12 hours. RE:BERRY Myeongdong is open 10am-8pm, 365 days a year including Korean holidays.
Book Your Rejuran for Under Eyes Korea Today
Consult with Head Director Dr. Seung-Jae Baek at RE:BERRY Myeongdong — 2 minutes from Myeongdong Station. Specialized Eye Rejuran protocol for dark circles, fine lines, and under-eye rejuvenation. Available 365 days in 8 languages.
Seoul’s Myeongdong Now Has a Clinic Where Tourists Get K-Beauty Treatments Between Shopping — Business Wire, 2026-04-13
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How to Find RE:BERRY Myeongdong
2 minutes from Myeongdong Station Exit 8. Premium flagship space with an all-black entrance you can't miss.
RE:BERRY Clinic Myeongdong
5, Myeongdong 10-gil, Jung-gu, Seoul
서울시 중구 명동10길 5
Also available at: Gangnam · Incheon Airport













