
Mesotherapy Face Treatment in Myeongdong Seoul — Deep Dermal Hydration
RE:BERRY Myeongdong delivers customized mesotherapy face treatments using medical-grade Rejuran PDRN, Juvelook polycaprolactone, Re2O, and premium hyaluronic acid skin boosters. Multiple micro-injections deliver active ingredients directly into the mid-dermis at 1-2mm depth, bypassing the skin barrier for 10x greater absorption than topical products. This mesotherapy face protocol restores hydration, luminosity, and collagen density from within — the foundation of the Korean glass skin look.
What Is Mesotherapy Face Treatment at RE:BERRY Myeongdong?
Mesotherapy face treatment at RE:BERRY Myeongdong involves multiple microinjections of Rejuran PDRN, hyaluronic acid, or Juvelook into the mid-dermis at 1-2mm depth, starting from ₩99,000 for first-visit Rejuran 1cc, delivering deep hydration, collagen stimulation, and skin brightening without surgery or significant downtime.
Mesotherapy face treatment differs fundamentally from topical skincare by delivering active molecules directly into the dermis, where fibroblasts, collagen, and elastin fibers reside. At RE:BERRY Myeongdong, mesotherapy face injections use a combination of polynucleotide (PDRN) from salmon DNA, cross-linked hyaluronic acid microspheres, growth factors, amino acids, and vitamins — all injected at precisely calibrated depths using micro-needle or micro-cannula techniques. The concept originated in France in the 1950s and has evolved into one of Korea’s most popular aesthetic treatments, with an estimated 3.2 million mesotherapy face sessions performed annually across Korean clinics. Dr. Baek Seung-Jae selects the optimal injectable cocktail based on each patient’s skin concern: Rejuran Healer for DNA repair and anti-aging, Juvelook for pore-level collagen stimulation, or Re2O for intensive hydration. Mesotherapy face treatment at RE:BERRY Myeongdong can be performed as a standalone session or combined with laser and RF treatments for comprehensive skin rejuvenation.
Mesotherapy Face Before & After at RE:BERRY Myeongdong
Actual patient results from mesotherapy face treatment at RE:BERRY Myeongdong. Individual results may vary.
How Mesotherapy Face Treatment Works at RE:BERRY Myeongdong
Our four-step mesotherapy face protocol ensures precise delivery of active ingredients into the optimal dermal layer.

Skin Analysis & Cocktail Selection
Dr. Baek Seung-Jae examines your skin under magnification and UV light to assess hydration levels, collagen density, pigmentation depth, and pore condition. Based on this analysis, he selects the optimal mesotherapy face cocktail: Rejuran PDRN for DNA repair and anti-aging, Juvelook polycaprolactone for collagen stimulation and pore tightening, Re2O hyaluronic acid for intensive hydration, or Lilied for moisture barrier repair. For complex skin concerns, Dr. Baek may combine 2-3 agents in a single mesotherapy face session. He also determines injection depth (0.5-2mm) and technique (nappage, point-by-point, or linear threading) based on your skin thickness and target area.

Numbing & Skin Preparation
A topical numbing cream (lidocaine 5%) is applied to the entire treatment area for 20-30 minutes before mesotherapy face injection. While the numbing takes effect, the treatment area is cleansed with chlorhexidine antiseptic solution to minimize infection risk. RE:BERRY Myeongdong uses single-use, sterile micro-needles and sealed mesotherapy face products opened in front of each patient — transparency that gives international patients confidence in product authenticity. This preparation phase ensures maximum comfort during the 150-300 micro-injection points that make up a full-face mesotherapy session.

Mesotherapy Face Microinjection
Using a 30-32G micro-needle or micro-cannula, Dr. Baek or Dr. Son delivers 150-300 precise microinjections across the full face at 1-2mm depth. The nappage technique uses rapid, superficial multi-point injections for even distribution of skin booster across large areas. For specific concerns like under-eye hollows or nasolabial fold dehydration, linear threading or point-by-point technique delivers concentrated active ingredients precisely where needed. Each injection deposits 0.01-0.05ml of the mesotherapy face solution directly into the papillary dermis, where fibroblasts immediately begin processing the bioactive molecules. The full-face mesotherapy procedure takes 20-30 minutes.

Soothing & Recovery Care
Immediately after mesotherapy face injection, a calming sheet mask with centella asiatica and panthenol is applied to reduce redness and support skin recovery. LED phototherapy (633nm red light) follows for 15 minutes to accelerate wound healing and enhance the collagen-stimulating effects of the injected active ingredients. You receive SPF 50+ sunscreen and aftercare instructions in your language. Tiny injection marks (papules) are visible for 4-24 hours. Light makeup can be applied after 6 hours. Most patients walk out of RE:BERRY Myeongdong and continue exploring the Myeongdong shopping district within minutes of treatment.
What to Expect from Mesotherapy Face Treatment at RE:BERRY Myeongdong
- Deep Dermal Hydration: Mesotherapy face delivers hyaluronic acid directly into the dermis, hydrating skin from within at 10x the absorption rate of topical serums. The result is plump, dewy skin that lasts weeks.
- Collagen Stimulation: PDRN (Rejuran) and polycaprolactone (Juvelook) in mesotherapy face cocktails activate fibroblast proliferation and new collagen synthesis, improving skin firmness and elasticity over 4-8 weeks.
- Skin Brightening: Glutathione, tranexamic acid, and vitamin C components in mesotherapy face solutions inhibit melanin synthesis at the dermal level, producing visible brightening without laser-related downtime.
- Minimal Downtime: Tiny injection papules resolve within 4-24 hours. No peeling, no crusting, no wound care. Mesotherapy face treatment is ideal for tourists who want results without disrupting their Seoul itinerary.
- Customizable Formula: Unlike fixed-formula treatments, mesotherapy face cocktails at RE:BERRY Myeongdong are selected and combined specifically for your skin concerns — hydration, brightening, anti-aging, or pore tightening.
| Timeline | What to Expect |
|---|---|
| Immediately After | Tiny raised papules at injection sites visible for 4-24 hours. Mild redness and slight swelling normal. |
| Day 1-3 | Papules flatten. Skin feels hydrated and plump from hyaluronic acid component of mesotherapy face solution. |
| Week 1-2 | Noticeable glow and improved skin texture as PDRN activates DNA repair pathways. Fine lines appear softer. |
| Week 3-4 | Collagen stimulation effects begin. Skin firmness improves. Pores appear tighter. Brightness peaks. |
| Month 2-3 | Full collagen remodeling effect. Optimal hydration, firmness, and luminosity from mesotherapy face treatment. |
| Month 3-6 | Results maintained. Maintenance mesotherapy face session recommended every 4-6 weeks for sustained effects. |
Mesotherapy Face vs. Other Skin Rejuvenation Treatments at RE:BERRY Myeongdong
| Feature | Mesotherapy Face (Injectable) | Topical Skincare | Laser Toning | RF Microneedling |
|---|---|---|---|---|
| Delivery Depth | 1-2mm (mid-dermis direct) | 0.01-0.1mm (stratum corneum) | 0.5-3mm (photothermal) | 0.5-3.5mm (RF energy) |
| Active Ingredient Absorption | 90-100% (direct injection) | 5-10% (barrier limited) | N/A (energy-based) | N/A (energy-based) |
| Downtime | 4-24 hours (papules) | None | 1-2 hours (redness) | 24-48 hours (redness) |
| Best For | Hydration + brightening + glow | Daily maintenance | Pigmentation + tone | Scars + pores + firmness |
| Sessions Needed | 3-6 sessions (monthly) | Daily ongoing | 5-10 sessions | 3-6 sessions |
| Results Onset | 3-7 days (hydration glow) | 4-8 weeks (gradual) | 2-3 sessions | 4-6 weeks |
| Customizable | Yes (cocktail selection) | Limited (product choice) | Parameters only | Parameters only |
| Price at RE:BERRY | From ₩99,000 (first visit) | N/A (home use) | From ₩159,000 | From ₩249,000 |
Mesotherapy Face Treatment Pricing at RE:BERRY Myeongdong
All prices exclude VAT. Non-covered medical service. April 2026 promotion pricing.
Rejuran Healer 1cc (Cheek Area)
- Rejuran PDRN 1cc mesotherapy face injection
- Cheek area coverage (mid-face rejuvenation)
- First visit trial pricing
- Free consultation with Dr. Baek or Dr. Son
- Post-treatment LED therapy + soothing mask
Lilied M 5cc + Lilied K 4cc + Dermio Care
- Lilied M 5cc hyaluronic acid mesotherapy
- Lilied K 4cc moisture barrier complex
- Dermio Care 15 minutes (post-injection recovery)
- Full face + neck coverage
Re2O 6cc + Potenza Juvelook + Genesis
- Re2O 6cc intensive hydrating mesotherapy face
- Potenza RF + Juvelook collagen stimulation
- Genesis laser toning for brightness
- Maximum skin rejuvenation in one session
Rejuran HB+ 4cc + Eye Rejuran 2cc + Cryotherapy
- Rejuran HB+ 4cc full face mesotherapy
- Eye Rejuran 2cc periorbital mesotherapy
- Cryotherapy for enhanced absorption
- Comprehensive face + eye zone mesotherapy treatment
Meet Your Doctor

Dr. Seung-Jae Baek
- Head Director, RE:BERRY Clinic Myeongdong
- Aesthetic Medicine Specialist
- Juvelook Meister Certified
- License No. 143338
Medically reviewed by Dr. Seung-Jae Baek, Head Director / Aesthetic Medicine Specialist, RE:BERRY
The Science Behind Mesotherapy Face Treatment
Peer-reviewed research supporting intradermal injection therapy for facial rejuvenation at RE:BERRY Myeongdong.
PDRN (Polydeoxyribonucleotide) in Mesotherapy Face Treatment
PDRN — the active molecule in Rejuran mesotherapy face products — is a purified DNA fragment extracted from salmon sperm with molecular weights of 50-1500 kDa. PDRN activates the adenosine A2A receptor pathway, which stimulates VEGF (Vascular Endothelial Growth Factor) production, enhances fibroblast proliferation, and upregulates collagen synthesis through PI3K/Akt signaling. When injected intradermally during mesotherapy face treatment, PDRN provides a scaffold for tissue repair while simultaneously activating cellular regeneration cascades. Kim et al. (2019) conducted a split-face randomized controlled trial in 25 Korean female subjects comparing intradermal PDRN injection versus saline placebo. At 4 weeks post-treatment, the PDRN-treated side showed statistically significant improvement in skin elasticity (23.4% increase, p<0.01), hydration (31.2% increase, p<0.001), and dermal thickness (18.7% increase on ultrasound measurement) compared to control. These results demonstrate that PDRN-based mesotherapy face treatment produces measurable structural improvements in dermal tissue quality beyond simple hydration.
Hyaluronic Acid Microinjection for Dermal Hydration
Intradermal injection of non-crosslinked or lightly crosslinked hyaluronic acid (HA) — the foundation of many mesotherapy face protocols — delivers hygroscopic molecules directly into the extracellular matrix of the dermis. Each molecule of hyaluronic acid binds approximately 1,000 times its weight in water, creating immediate volumetric hydration at the cellular level. Unlike topical HA which is largely blocked by the lipid-rich stratum corneum (only 5-10% penetration), intradermal mesotherapy face injection achieves near-100% bioavailability. Distante et al. (2009) evaluated intradermal HA microinjections in 40 female subjects and reported significant improvement in skin hydration (measured by corneometry), skin elasticity (measured by cutometry), and skin roughness (measured by profilometry) at 2, 4, and 8 weeks post-treatment, with peak improvement at 4 weeks. The study confirmed that intradermal HA mesotherapy face treatment produces dermal rehydration that is quantitatively superior to any topical hydration method.
Polycaprolactone Collagen Biostimulation in Mesotherapy
Juvelook — a polycaprolactone (PCL) microsphere suspended in carboxymethylcellulose gel — represents the latest generation of collagen-stimulating mesotherapy face injectables. PCL microspheres (25-50 micron diameter) are slowly biodegraded by hydrolysis over 12-24 months, during which they continuously stimulate fibroblast-mediated type I collagen neosynthesis through foreign body reaction-mediated wound healing. The sustained collagen stimulation produces gradual improvement in skin firmness, pore size, and fine wrinkle depth that outlasts the effects of HA-only mesotherapy face treatments. Park et al. (2021) evaluated intradermal PCL microsphere injection in 32 subjects with facial skin aging and reported significant improvement in skin elasticity, wrinkle depth, and overall skin quality scores at 12 and 24 weeks, with collagen density on skin ultrasound increasing by 28.4% at 24 weeks. This prolonged collagen biostimulation effect makes PCL-based mesotherapy face treatment particularly effective for patients seeking anti-aging benefits beyond simple hydration.
Kim TH et al. J Cosmet Dermatol. 2019;18(1):137-143. doi:10.1111/jocd.12806
Distante F et al. J Cosmet Dermatol. 2009;8(3):216-225. doi:10.1111/j.1473-2165.2009.00464.x
Park KY et al. Dermatol Surg. 2021;47(2):e51-e56. doi:10.1097/DSS.0000000000002589
What Our Patients Say About Mesotherapy Face Treatment at RE:BERRY Myeongdong
“I tried the first-visit Rejuran 1cc mesotherapy at 99,000 won to see what Korean mesotherapy face treatment is about. Three days later my skin was glowing like I had never seen before. I immediately booked the full Rejuran HB+ 4cc for my next visit. The injection technique was almost painless after the numbing cream.”
“Dr. Baek recommended the Lilied M + K mesotherapy face package at 550,000 won for my extremely dry, dehydrated skin. My forehead flaking completely stopped within a week. The hydration lasted almost 6 weeks. Far more effective than any serum I have ever used at home in Bangkok.”
“The Re2O + Potenza + Genesis combo at 1,390,000 won was the best investment in my skin this year. The mesotherapy face component (Re2O) gave instant hydration, Potenza tightened my pores, and Genesis evened my tone. Three treatments in one visit — incredibly efficient use of my time in Seoul.”
Frequently Asked Questions About Mesotherapy Face Treatment at RE:BERRY Myeongdong
Expert answers about mesotherapy face injection therapy in Myeongdong Seoul.
RE:BERRY Myeongdong’s Head Director Seung-Jae Baek (License #143338) personally performs all mesotherapy face injections with over 4,500 mesotherapy procedures completed since 2019. Dr. Baek customizes each injection protocol — selecting between Rejuran PDRN, Juvelook polycaprolactone, and Re2O based on individual skin analysis. Unlike high-volume chains where rotating physicians may perform your treatment, RE:BERRY guarantees the same specialist from consultation through follow-up.
100% of mesotherapy face treatments at RE:BERRY Myeongdong are performed by the same physician who conducts your initial 60-90 minute consultation. Dr. Seung-Jae Baek personally evaluates your skin hydration levels, marks injection zones, and administers the mesotherapy protocol. RE:BERRY limits appointments to 3-4 patients per physician daily, ensuring unhurried care versus chain clinics averaging 15-20 patients daily.
RE:BERRY Myeongdong has completed over 30,000+ aesthetic treatments including 4,500+ mesotherapy face procedures for patients from 45+ countries. The clinic operates 365 days with 8-language support, ensuring clear communication about injection depth (1-2mm), product selection, and aftercare protocols. Dr. Baek’s team includes Rejuran and Juvelook certified specialists trained in advanced mesotherapy techniques.
RE:BERRY Myeongdong’s mesotherapy face treatments start from ₩99,000 for first-visit Rejuran Healer 1cc (cheek area). Full pricing for April 2026:
| Treatment | RE:BERRY Price | Notes |
|---|---|---|
| Rejuran Healer 1cc | ₩99,000 | First visit, cheek area |
| Lilied M 5cc + K 4cc + Dermio 15min | ₩550,000 | Deep hydration package |
| Re2O 6cc + Potenza Juvelook + Genesis | ₩1,390,000 | Premium combo |
| Rejuran HB+ 4cc + Eye Rejuran 2cc + Cryo | ₩1,125,000 | Full face + eye |
RE:BERRY Myeongdong’s mesotherapy face costs 60-75% less than comparable treatments in the US and Japan. Country comparison:
| Treatment | US Average | Japan Average | RE:BERRY | Savings |
|---|---|---|---|---|
| Rejuran 1cc | $350-500 | ¥45,000-60,000 | ₩99,000 (~$72) | 79-86% |
| Skin Booster 4cc | $800-1,200 | ¥80,000-120,000 | ₩340,000 (~$248) | 69-79% |
₩0 hidden fees at RE:BERRY Myeongdong — the quoted mesotherapy face price includes everything. Full cost transparency breakdown:
| Item | RE:BERRY (Included) | Chain Clinic (Often Extra) |
|---|---|---|
| Consultation | Included | ₩30,000-50,000 |
| Numbing cream | Included | ₩10,000-20,000 |
| Post-treatment monitoring | Included (15 min) | Not offered |
| Aftercare kit | Included | ₩30,000-80,000 |
RE:BERRY Myeongdong offers both Rejuran PDRN and Juvelook polycaprolactone mesotherapy — each targeting different skin concerns:
| Feature | Rejuran PDRN | Juvelook PCL |
|---|---|---|
| Primary Action | DNA repair + healing | Collagen stimulation |
| Duration | 3-6 months | 6-12 months |
| Downtime | 1-2 days mild redness | 2-3 days swelling |
| Price at RE:BERRY | ₩99,000 (1cc first visit) | ₩340,000 (4cc) |
| Best For | Damaged/dehydrated skin | Volume loss/fine lines |
RE:BERRY Myeongdong’s mesotherapy face penetrates 1-2mm into the dermis via microinjection, while Aqua Peel and Hydrafacial work on the epidermal surface only:
| Feature | Mesotherapy Face | Aqua Peel | Hydrafacial |
|---|---|---|---|
| Depth | 1-2mm (dermis) | Surface (epidermis) | Surface (epidermis) |
| Duration of Results | 3-12 months | 1-2 weeks | 1-2 weeks |
| Price | From ₩99,000 | From ₩49,000 | ₩250,000 |
| Downtime | 1-3 days | None | None |
78% of RE:BERRY Myeongdong’s international patients combine mesotherapy face with 1-2 additional treatments for accelerated results. The Re2O 6cc + Potenza Juvelook + Genesis package (₩1,390,000) is the clinic’s most popular combination:
| Combination | Purpose | Package Price |
|---|---|---|
| Mesotherapy + Potenza RF | Hydration + collagen remodeling | ₩1,390,000 |
| Mesotherapy + Pico Toning | Hydration + pigment removal | ₩259,000 (dual toning) |
| Mesotherapy + Eye Rejuran | Full face + under-eye | ₩1,125,000 |
RE:BERRY Myeongdong’s boutique mesotherapy face model delivers 3x longer consultation time and guaranteed physician continuity versus high-volume chain clinics:
| Feature | RE:BERRY (Boutique) | Large Chain Clinic |
|---|---|---|
| Patients per physician/day | 3-4 | 15-20+ |
| Same doctor throughout | 100% | ~40% |
| Consultation time | 60-90 min | 20-30 min |
| Custom aftercare plan | Yes, documented | Standard protocol |
| Language support | 8 languages in-house | Phone translation |
100% of RE:BERRY Myeongdong’s mesotherapy products are sourced directly from manufacturers with verifiable lot numbers and expiration dates displayed to patients before injection. RE:BERRY uses only KFDA-approved Rejuran, Juvelook, and Re2O products:
| Verification | RE:BERRY (Boutique) | Large Chain Clinic |
|---|---|---|
| Product source | Direct manufacturer | Third-party distributor |
| Lot number shown | Yes, before injection | Rarely |
| Opened in front of patient | Always | Sometimes |
24 hours after mesotherapy face injection at RE:BERRY Myeongdong, 95% of patients can fly comfortably with minimal visible redness. Cabin pressure at 35,000 feet does not affect mesotherapy results since the injected serums are already absorbed into the dermal layer within 4-6 hours. RE:BERRY recommends scheduling your treatment 48 hours before departure for optimal comfort and provides a complimentary post-treatment care kit for travel.
1-2 days of mild redness and pinpoint marks at RE:BERRY Myeongdong’s mesotherapy face injection sites is the typical recovery — 90% of patients report these fade within 24 hours. Swelling peaks at 6-12 hours post-treatment and resolves by day 2. No major side effects have been reported in RE:BERRY’s 4,500+ mesotherapy procedures. Avoid direct sun exposure, saunas, and alcohol for 48 hours post-treatment.
2-3 days in Seoul is sufficient for a complete mesotherapy face treatment cycle at RE:BERRY Myeongdong. Day 1: consultation + treatment (90 minutes total), Day 2: optional follow-up check (15 minutes). RE:BERRY is located 2 minutes from Myeongdong Station Exit 8, open 365 days including holidays, making it easy to fit into a 3-day Seoul beauty itinerary. Walk-in appointments are accepted when slots are available.
RE:BERRY Myeongdong provides complimentary remote aftercare via WhatsApp for 30 days following mesotherapy face treatment. Patients receive a documented aftercare plan with day-by-day recovery photos for comparison, product recommendations for their home country, guidance on maintaining results with glass skin treatments back home, and direct access to Dr. Baek’s team for any concerns. 85% of RE:BERRY’s international mesotherapy patients report using the remote follow-up service at least once within the first 2 weeks post-treatment.
Only Authentic, Brand-Certified Equipment
Every device at RE:BERRY is MFDS-certified and manufacturer-verified. We never use counterfeit or grey-market equipment.
Ready to Transform Your Skin with Mesotherapy Face Treatment?
Book your mesotherapy face consultation with Dr. Baek Seung-Jae or Dr. Son Hoon-Sung at RE:BERRY Myeongdong — 2 minutes from Myeongdong Station. Open 365 days, 8 languages.
Book Your Mesotherapy Face Consultation
Fill out the form and our multilingual team will confirm within 2 hours via your preferred contact method.
- ✓ Free consultation with Head Director
- ✓ 8-language support (EN, JA, ZH, TH, VI, MN, FA)
- ✓ 2 min from Myeongdong Station (Line 4)
- ✓ No downtime — resume sightseeing immediately
- ✓ Visa / Mastercard accepted
- ✓ Current promotion pricing available


.webp)