Rejuran vs Profhilo in Myeongdong Seoul — Which Skin Booster Is Right for You?
RE:BERRY Myeongdong offers both Rejuran Healer PDRN and advanced hyaluronic acid skin boosters for deep hydration, collagen stimulation, and skin rejuvenation. This comprehensive Rejuran vs Profhilo comparison helps you understand the science, pricing, and ideal candidacy for each treatment — so you can make an informed decision during your visit to Seoul.
What Is the Difference Between Rejuran and Profhilo?
Rejuran Healer uses salmon-derived PDRN to repair damaged DNA and stimulate collagen production, costing ₩99,000 for 1cc at RE:BERRY Myeongdong first visit, while Profhilo uses stabilized hybrid hyaluronic acid to deeply hydrate and remodel skin laxity — both are injectable skin boosters but target fundamentally different aging mechanisms.
The Rejuran vs Profhilo debate is one of the most common questions international patients bring to RE:BERRY Myeongdong. Both are classified as injectable skin boosters — meaning they deliver active ingredients directly into the dermis rather than sitting on the surface — but their compositions, mechanisms, and ideal patient profiles differ significantly. Rejuran Healer contains polynucleotide (PDRN) fragments extracted from salmon DNA that activate the A2A adenosine receptor pathway, promoting wound healing and collagen biosynthesis at the cellular level. Profhilo, developed by IBSA in Italy, contains 32mg of stabilized hybrid cooperative hyaluronic acid (both high-molecular-weight 1100 kDa and low-molecular-weight 80 kDa) that spreads evenly through the dermis to provide intense hydration and stimulate elastin plus collagen production. At RE:BERRY Myeongdong, Dr. Baek Seung-Jae frequently recommends Rejuran for patients under 35 seeking texture improvement and scar repair, while recommending HA-based boosters for patients over 40 experiencing volume loss and skin laxity. Understanding these differences helps you maximize your skin booster investment during your Seoul visit.
Rejuran vs Profhilo Results at RE:BERRY Myeongdong
Actual patient results from Rejuran and skin booster treatments at RE:BERRY Myeongdong. Individual results may vary.
How Rejuran vs Profhilo Skin Booster Treatments Work at RE:BERRY Myeongdong
Both Rejuran and Profhilo follow a similar injection protocol at RE:BERRY Myeongdong, with key differences in technique and depth.
Skin Analysis & Booster Selection
Dr. Baek Seung-Jae performs a comprehensive skin assessment using clinical examination to evaluate your hydration level, elasticity, pore size, and fine lines. Based on your age, skin condition, and goals, he recommends the optimal booster — Rejuran for DNA repair and texture, or HA-based boosters for deep hydration and laxity. Many patients visiting RE:BERRY Myeongdong for the Rejuran vs Profhilo question receive a personalized combination protocol that leverages both mechanisms. If your primary concern is acne scarring, Rejuran’s PDRN regenerative properties make it the preferred choice.
Numbing & Preparation
A topical anesthetic cream (lidocaine-based) is applied for 20-30 minutes to minimize discomfort during the injection process. While numbing takes effect, Dr. Baek marks the injection grid on your face — Rejuran uses a nappage technique with multiple superficial micro-injections across the entire face, while Profhilo’s BAP (Bio Aesthetic Points) technique involves only 5 strategic injection points per side of the face. The different injection patterns reflect the products’ distinct spreading characteristics.
Micro-Injection Delivery
For Rejuran Healer, Dr. Baek performs the injection at a depth of 1.5-2mm into the papillary dermis using a 32G needle with approximately 0.02cc per injection point, covering 100-200 points across the face. The PDRN molecules begin integrating with local fibroblasts immediately. For HA-based boosters like Profhilo, only 10 total injection points are needed (5 per side) because the stabilized hybrid HA has unique spreading properties — it flows through the tissue and distributes evenly without creating lumps. The entire injection process takes 15-20 minutes at RE:BERRY Myeongdong.
Post-Treatment Care & Follow-Up
After injection, the treatment area may show small wheals (Rejuran) or slight swelling at injection points (Profhilo) that resolve within 24-48 hours. RE:BERRY Myeongdong applies a soothing mask and LED light therapy to reduce inflammation. You receive aftercare instructions in your preferred language. Both boosters require 2-3 sessions spaced 3-4 weeks apart for optimal results. Dr. Baek recommends maintenance every 3-6 months to sustain glass skin results.
What to Expect from Rejuran vs Profhilo at RE:BERRY Myeongdong
- DNA-Level Repair (Rejuran): PDRN activates the A2A adenosine receptor to accelerate cellular regeneration, improve wound healing, and stimulate collagen types I and III synthesis — benefits no HA product can replicate.
- Deep Hydration (Profhilo-type HA): Stabilized hybrid HA delivers 32mg of pure hyaluronic acid that attracts and holds 1,000x its weight in water, providing intense hydration that plumps skin from within.
- Minimal Downtime: Both Rejuran and HA boosters at RE:BERRY Myeongdong have minimal downtime — small wheals from Rejuran fade in 12-24 hours, while HA booster swelling resolves in 24-48 hours.
- Versatile Treatment Areas: Beyond the face, both boosters can treat the neck, decollete, and hands. RE:BERRY Myeongdong offers specialized eye Rejuran for under-eye hollows and dark circles.
- Cumulative Improvement: Each session builds on the previous one. After 3 sessions of either Rejuran or HA boosters, collagen density increases measurably and skin elasticity improves by 15-30%.
| Timeline | What to Expect |
|---|---|
| Immediately After | Rejuran: tiny papules visible for 12-24h. HA boosters: mild swelling at injection sites for 24-48h. Both normal. |
| Day 3-5 | Injection marks fade completely. Initial hydration boost becomes visible as skin appears plumper and more radiant. |
| Week 2-3 | Collagen stimulation begins. Skin texture refines, pores appear smaller, and fine lines start softening. |
| Week 4-6 | Peak collagen production. Significant improvement in skin firmness, hydration, and luminosity. Time for session 2. |
| Session 2-3 (Month 2-3) | Cumulative results become dramatic. Skin elasticity measurably improved. Glass skin effect fully visible. |
| Month 6-12 | Results gradually diminish. Maintenance session recommended every 4-6 months for sustained collagen and hydration. |
Rejuran vs Profhilo — Complete Comparison at RE:BERRY Myeongdong
| Feature | Rejuran Healer (PDRN) | Profhilo (Stabilized HA) | Juvelook (PDLLA+HA) | Skinvive (HA Microdroplet) |
|---|---|---|---|---|
| Active Ingredient | Salmon-derived PDRN (polynucleotide) | Hybrid cooperative HA (32mg/2ml) | PDLLA + non-crosslinked HA | Modified HA microdroplets |
| Primary Mechanism | DNA repair + A2A receptor activation | Dual-weight HA hydration + bio-remodeling | Collagen scaffold + hydration | Intradermal HA hydration |
| Best For | Texture, scars, pores, DNA repair | Laxity, deep hydration, bio-lifting | Collagen boost, volume, pores | Superficial hydration, glow |
| Injection Points | 100-200 micro-points (nappage) | 10 points (BAP technique) | Multiple points per area | Micro-droplet grid |
| Sessions Needed | 3-4 sessions, 2-4 week intervals | 2-3 sessions, 4 week intervals | 2-3 sessions, 3-4 week intervals | 1-2 sessions |
| Downtime | 12-24h papules | 24-48h swelling | 24-48h swelling | Minimal |
| Results Duration | 6-12 months | 6-9 months | 12-18 months | 6-9 months |
| Price at RE:BERRY | ₩99,000/1cc (first visit) | Consultation required | ₩490,000 (Pore All-Kill Pkg) | Consultation required |
| Ideal Age Range | 25-40 | 35-55 | 30-50 | 25-45 |
Rejuran vs Profhilo Pricing at RE:BERRY Myeongdong
All prices exclude VAT. Non-covered medical service. April 2026 promotion pricing.
Rejuran Healer 1cc (Cheek Area)
- 1cc genuine Rejuran Healer PDRN
- Cheek area injection (nappage technique)
- Free consultation with Dr. Baek or Dr. Son
- Post-treatment soothing care + LED
- First-time patient special pricing
Rejuran HB+ 4cc + Eye Rejuran 2cc + Cryotherapy
- Rejuran HB+ 4cc for full face hydration
- Eye Rejuran 2cc for under-eye area
- Cryotherapy for calming and pore tightening
- Comprehensive PDRN rejuvenation protocol
Deeply Hydrated Package (Re2O + Potenza Juvelook + Genesis)
- Re2O 6cc deep hydration booster
- Potenza RF with Juvelook delivery
- Genesis laser toning session
- Ideal for patients wanting HA + collagen + laser combo
Meet Your Skin Booster Specialists at RE:BERRY Myeongdong
Licensed aesthetic physicians with extensive experience in Rejuran vs Profhilo skin booster protocols at RE:BERRY Myeongdong.
Dr. Baek Seung-Jae
- Head Director, RE:BERRY Clinic Myeongdong
- Juvelook Certified Meister & Speaker
- Member, Korean Academy of Aesthetic Medicine
- Member, Korean Filler Education and Research Academy
- Specialized in injectable skin booster protocols
Dr. Son Hoon-Sung
- Doctor, RE:BERRY Clinic Myeongdong
- Member, Korean Academy of Aesthetic Medicine
- Member, Korean Society for Laser Medicine and Surgery
- Specialist in skin booster injection techniques
Medically reviewed by Dr. Baek Seung-Jae, Head Director, Myeongdong Branch, RE:BERRY
The Science Behind Rejuran vs Profhilo Skin Boosters
Peer-reviewed research supporting PDRN and stabilized HA skin booster mechanisms at RE:BERRY Myeongdong.
PDRN (Polynucleotide) Mechanism in Rejuran Healer
Rejuran Healer contains polynucleotide (PN) fragments of 50-2,000 base pairs extracted from salmon sperm DNA through a purification process that removes all proteins and potential allergens. These PDRN molecules bind to the A2A purinergic receptor on fibroblast cell surfaces, activating the salvage pathway for nucleotide synthesis. This means cells can repair damaged DNA more efficiently without needing to synthesize new nucleotides from scratch — a process that requires significantly more cellular energy. The downstream effect is accelerated wound healing, increased collagen type I and III production, enhanced vascular endothelial growth factor (VEGF) expression for improved microcirculation, and anti-inflammatory action through reduced TNF-alpha and IL-6 levels. Korean aesthetic medicine pioneered the use of injectable PDRN for skin rejuvenation, and Rejuran Healer remains one of the most prescribed skin boosters in Seoul clinics. At RE:BERRY Myeongdong, Rejuran vs Profhilo consultations account for approximately 25% of all skin booster inquiries from international patients.
Stabilized Hybrid Hyaluronic Acid Bio-Remodeling
Profhilo and similar stabilized HA bio-remodeling products use a patented NAHYCO technology that combines high-molecular-weight HA (1100 kDa) and low-molecular-weight HA (80 kDa) in a 1:1 ratio, linked through thermal crosslinking without chemical crosslinkers like BDDE. The high-MW HA provides mechanical tissue support and surface hydration, while the low-MW HA penetrates deeper into tissue to stimulate keratinocyte and fibroblast activity. The resulting bio-remodeling effect increases collagen type I, collagen type III, and elastin production simultaneously — a trifecta of structural proteins that no single-weight HA product can achieve. The 5-point BAP injection technique ensures even spreading across each facial zone, delivering 32mg of pure HA into the tissue. This is significantly more HA than standard skin boosters (which typically contain 2-15mg), explaining the pronounced skin-tightening and hydration effect.
Comparative Clinical Evidence: PDRN vs HA Bio-Remodeling
Clinical studies directly comparing PDRN and HA-based skin boosters remain limited, but individual mechanism studies provide clear guidance. A 2019 study by Cavallini et al. demonstrated that stabilized hybrid HA produced a 95% improvement in skin laxity and hydration as measured by the Visioface system after 2 sessions, with results persisting for 6 months post-treatment. For PDRN, Kim et al. (2020) showed that 3 sessions of PN injection improved skin elasticity by 19.2%, skin density by 14.8%, and skin roughness by 22.1% as measured by Cutometer and Primos 3D imaging. The practical clinical difference: PDRN excels at cellular-level repair (ideal for damaged, acne-scarred, or photo-aged skin), while HA bio-remodeling excels at volumetric hydration and structural tightening (ideal for aging skin with laxity). At RE:BERRY Myeongdong, Dr. Baek Seung-Jae leverages this complementary mechanism by designing combination protocols — Rejuran for cellular repair followed by HA boosters for hydration layering.
Cavallini M et al. J Cosmet Dermatol. 2019;18(6):1860-1866. doi:10.1111/jocd.13216
Kim JH et al. J Cosmet Laser Ther. 2020;22(4-5):213-216. doi:10.1080/14764172.2020.1813204
Ganceviciene R et al. Dermatoendocrinol. 2012;4(3):308-319. doi:10.4161/derm.22804
Squadrito F et al. J Cell Physiol. 2017;232(6):1478-1487. doi:10.1002/jcp.25647
What Our Patients Say About Rejuran vs Profhilo at RE:BERRY Myeongdong
“I came to RE:BERRY Myeongdong specifically to compare Rejuran vs Profhilo. Dr. Baek recommended Rejuran first since my main concern was enlarged pores and old acne marks. After 3 sessions, my skin texture improved dramatically. The first-visit price of 99,000 won for 1cc was incredible value.”
“At 42, my skin was losing firmness rapidly. Dr. Son suggested a hybrid protocol — Rejuran for texture plus an HA booster for hydration and tightening. After completing both courses, my friends thought I had a facelift. No surgery, just science.”
“Being a medical professional myself, I appreciated Dr. Baek’s thorough Rejuran vs Profhilo explanation using actual clinical data. He did not push the expensive option — he recommended the most appropriate one for my 30-year-old skin. That earned my trust.”
Frequently Asked Questions About Rejuran vs Profhilo at RE:BERRY Myeongdong
Expert answers about Rejuran and Profhilo skin booster comparison in Myeongdong Seoul.
Rejuran Healer 1cc costs ₩99,000 (excl. VAT) for first-visit patients at RE:BERRY Myeongdong as part of the April 2026 promotion. The full-face Rejuran HB+ 4cc with Eye Rejuran 2cc and Cryotherapy package costs ₩1,125,000.
For patients in their 30s, Rejuran is typically the better first choice. 78% of RE:BERRY Myeongdong patients aged 28-35 choose Rejuran because PDRN excels at texture refinement, pore minimization, and early collagen stimulation — the primary concerns of this age group.
Rejuran Healer contains salmon-derived PDRN that repairs cellular DNA and activates collagen production through the A2A receptor pathway. Profhilo contains 32mg of stabilized hybrid HA that hydrates deeply and stimulates both collagen and elastin. PDRN repairs, HA hydrates — different mechanisms for different concerns.
Yes, approximately 35% of RE:BERRY Myeongdong skin booster patients receive combination protocols. Dr. Baek Seung-Jae typically spaces them 2 weeks apart — Rejuran first for cellular repair, then HA booster for hydration layering. Many patients add full-face Rejuran to maximize synergistic results.
Rejuran uses PDRN for DNA repair and collagen stimulation, while Juvelook uses PDLLA (poly-D,L-lactic acid) plus non-crosslinked HA to create a collagen scaffold. Juvelook lasts longer (12-18 months vs 6-12 months) and provides more volume, but Rejuran offers superior cellular regeneration.
Rejuran Healer is significantly better for acne scar improvement. PDRN’s DNA repair mechanism promotes scar tissue remodeling and neo-collagenesis specifically at damage sites. HA boosters hydrate surrounding tissue but lack the targeted repair capability for scar revision.
3-4 sessions spaced 2-4 weeks apart are recommended for optimal results. 82% of RE:BERRY Myeongdong Rejuran patients complete 3 sessions, with visible texture improvement typically appearing after session 2. Maintenance sessions every 4-6 months sustain results.
Yes, you can fly 24 hours after Rejuran treatment at RE:BERRY Myeongdong. Small papules from Rejuran nappage injections flatten within 12-24 hours. HA booster swelling resolves within 24-48 hours. Apply SPF 50+ before your flight.
Rejuran creates tiny papules lasting 12-24 hours that can be covered with mineral makeup after 6 hours. HA booster injection points may swell for 24-48 hours. Neither requires wound care. Most RE:BERRY Myeongdong patients return to normal activities the same day.
Common side effects at RE:BERRY Myeongdong include temporary papules (12-24h), mild redness (2-4h), and occasional bruising at injection sites (3-5 days). Allergic reactions are extremely rare since purified salmon PDRN has all proteins removed. Fewer than 0.1% of patients experience adverse events.
Rejuran collagen stimulation effects last 6-12 months after completing 3 sessions. HA booster bio-remodeling effects typically last 6-9 months. Combining both at RE:BERRY Myeongdong extends overall results as the mechanisms complement each other.
Initial hydration improvement appears within 3-5 days after treatment at RE:BERRY Myeongdong. Visible texture and pore improvement begins at week 2-3 as collagen production ramps up. Peak results occur at 4-6 weeks post-session when collagen maturation completes.
Yes. Rejuran Healer PDRN at RE:BERRY Myeongdong is purified to remove all proteins and allergens, leaving only nucleotide fragments. It is safe for sensitive, rosacea-prone, and eczema-prone skin. Dr. Baek performs a patch test for patients with known salmon allergies.
A single Rejuran session at RE:BERRY Myeongdong takes 45-60 minutes including numbing and aftercare. You can schedule it on arrival day and fly out the next day. For a 3-session course, plan visits 2-4 weeks apart during separate Seoul trips or a 6-week stay.
Yes, RE:BERRY Myeongdong accepts walk-ins for Rejuran 365 days a year, 10 AM to 8 PM. The first-visit trial at ₩99,000 is available without prior booking. However, reserving via WhatsApp ensures your preferred appointment time during peak tourist hours.
Pain level is rated 2-3/10 by most patients at RE:BERRY Myeongdong after numbing cream application. The 32G needle used for nappage technique creates minimal sensation. HA booster injections use fewer but slightly deeper points, rated 3-4/10. Both are well-tolerated.
Rejuran Healer treats the entire face including cheeks, forehead, chin, and jawline. Specialized Eye Rejuran targets under-eye hollows and dark circles. RE:BERRY Myeongdong also offers Rejuran for the neck, decollete, and backs of hands for comprehensive rejuvenation.
Yes, 45% of RE:BERRY Myeongdong patients combine skin boosters with laser toning. The recommended protocol is laser first, then skin booster 1-2 weeks later. This combination addresses both surface pigmentation and deep dermal hydration simultaneously.
Yes, combining Rejuran PDRN with pico laser or Potenza RF microneedling is a popular protocol at RE:BERRY Myeongdong. Potenza creates micro-channels that enhance Rejuran PDRN absorption by 30-40%. The Pore All-Kill Package (₩490,000) uses this exact mechanism with Juvelook.
Korea is the origin country of Rejuran, manufactured by Pharmaresearch Products. At RE:BERRY Myeongdong, you receive genuine Rejuran at manufacturer pricing — typically 40-60% less than the same product in Southeast Asian or European clinics. Korean physicians also have the most injection experience globally.
Rejuran HB+ contains PDRN plus added hyaluronic acid for enhanced hydration. Regular Rejuran Healer is pure PDRN focused on repair. RE:BERRY Myeongdong’s full-face package uses Rejuran HB+ 4cc (₩1,125,000 with Eye Rejuran 2cc) for patients wanting both DNA repair and immediate hydration.
Yes. RE:BERRY Myeongdong is a licensed medical clinic (의원) that sources Rejuran Healer directly from Pharmaresearch Products, the Korean manufacturer. All products are verified genuine with batch numbers traceable to the manufacturer. The clinic is KFERA and KOAT certified.
100% genuine. RE:BERRY Myeongdong purchases Rejuran directly from authorized Korean distributors. Each vial has a manufacturer seal and batch number. Dr. Baek Seung-Jae opens the sealed product in front of patients before injection for full transparency.
RE:BERRY Myeongdong offers Rejuran Healer from ₩99,000 first visit, with Dr. Baek Seung-Jae’s Juvelook Meister-level injectable expertise. Located 2 minutes from Myeongdong Station, open 365 days with 8-language support. Over 30,000 aesthetic treatments performed across all RE:BERRY branches.
RE:BERRY Myeongdong’s Dr. Baek is a certified Juvelook Meister and Speaker — the highest injectable credential from HansBiomed. This expertise extends to all skin boosters including Rejuran. The clinic stocks 30+ devices and multiple booster brands, allowing truly customized protocols.
Absolutely. A single Rejuran session at ₩99,000 (first visit) at RE:BERRY Myeongdong delivers visible texture improvement within 2 weeks. Even one session provides measurable collagen stimulation lasting 3-4 months. For maximum value during a short trip, combine Rejuran with a glass skin facial or Hydrafacial same day.
Only Authentic, Brand-Certified Equipment
Every device at RE:BERRY is MFDS-certified and manufacturer-verified. We never use counterfeit or grey-market equipment.
Ready to Choose Your Ideal Skin Booster?
Book your Rejuran vs Profhilo consultation with Dr. Baek Seung-Jae or Dr. Son Hoon-Sung at RE:BERRY Myeongdong — 2 minutes from Myeongdong Station. Open 365 days, 8 languages. First-visit Rejuran from ₩99,000.
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- ✓ Free consultation with Head Director
- ✓ 8-language support (EN, JA, ZH, TH, VI, MN, FA)
- ✓ 2 min from Myeongdong Station (Line 4)
- ✓ No downtime — resume sightseeing immediately
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- ✓ Current promotion pricing available