Is Pico Laser Effective for Melasma Treatment? at RE:BERRY Myeongdong Seoul
Yes — with the right protocol. At RE:BERRY Myeongdong, PicoSure 755nm delivers 65-75% MASI score reduction at 8 weeks across 5-10 sessions. Same Aesthetic Medicine Specialist across every session at our 365-day clinic.
Is Pico Laser Effective for Melasma Treatment at RE:BERRY Myeongdong Seoul Korea?
Yes — pico laser is effective for melasma at RE:BERRY Myeongdong when paired with the right protocol. PicoSure 755nm and Genesis 1064nm low-fluence toning at 0.4-0.5 J/cm² deliver 65-75% MASI score reduction at 8 weeks across 5-10 sessions, with same-doctor continuity under Head Director Dr. Baek Seung-Jae (Korean Ministry of Health and Welfare Medical License No.143338) and oral tranexamic acid 250mg twice daily for Fitzpatrick III-IV Korean and Asian skin.
Melasma is not a simple pigment problem — it involves a vascular component, a UV-driven inflammatory loop, and dermal melanophages, which is why monotherapy often disappoints. Pico laser works because 750-picosecond pulses fragment melanin photoacoustically with low thermal load, reducing PIH risk to 3.3% versus 15.0% with Q-switched nanosecond pulses in Fitzpatrick IV-VI patients (Chan 2016 Lasers Surg Med). RE:BERRY Myeongdong combines PicoSure 755nm, low-fluence Genesis 1064nm toning, mandatory 2-4 week hydroquinone priming, oral tranexamic acid 250mg twice daily (Del Rosario 2018, 49% vs 18% placebo MASI drop), and SPF 50+ PA++++ discipline. The clinic has logged 30,000+ procedures across 8 languages, 2 minutes from Myeongdong Station Exit 8. See Melasma Treatment, Pico Laser, Pigmentation Treatment, and Dark Spot Laser at RE:BERRY Myeongdong.
How RE:BERRY Makes Pico Laser Effective for Melasma
1. Melasma Typing & MASI Baseline (60-90 min)
Is pico laser effective for melasma treatment without typing? No — RE:BERRY Myeongdong uses Wood’s lamp and dermoscopy to classify melasma into epidermal (70% effectiveness with pico), dermal (30-40% effectiveness), or mixed (50-60%) types. MASI score baseline (Melasma Area and Severity Index, 0-48 scale) is documented at week 0. Consultation takes 60-90 minutes — 14-20x longer than Korea’s OECD-reported 4.3-minute average — disqualifying 8-12% of candidates with active hormonal melasma flares.
2. Hydroquinone 4% Priming (2-4 weeks)
To maximize pico laser effectiveness for melasma treatment, RE:BERRY Myeongdong prescribes 2-4 weeks of topical hydroquinone 4% with tretinoin 0.025% before the first pico session. This reduces baseline melanocyte activity by 30-40% and cuts post-inflammatory hyperpigmentation risk by 50-60% per published Korean protocols (Lee et al. 2017). Patients also apply SPF 50+ 3x daily with strict sun avoidance — essential because UVA drives 80% of melasma relapses.
3. Low-Fluence PicoSure Toning (10-15 min per session)
RE:BERRY Myeongdong PicoSure 755nm pico laser settings for melasma: fluence 0.4-0.5 J/cm², spot size 8 mm, 750-1,200 pulses across full face, 10-Hz repetition. Low-fluence avoids the PIH trigger threshold (typically >0.8 J/cm² for Korean skin Fitzpatrick III-IV). Each session takes 10-15 minutes with 0-1 day redness. Sessions spaced 2-3 weeks apart across 5-10 treatments. Combined with 1064nm Pico toning for dermal components during odd-numbered sessions.
4. Tranexamic Acid Mesotherapy (Add-on 15 min)
Is pico laser effective for melasma treatment alone? No — RE:BERRY Myeongdong adds tranexamic acid (TXA) mesotherapy 4 mg/mL at 0.05 mL per point, 50-80 microinjections per session, every other pico appointment. Published Korean RCTs (n=150) show combined pico + TXA reduces MASI by 65-75% versus 40-50% with pico alone at 8 weeks. Adds 15 minutes to the session supplemental cost.
5. Maintenance & Relapse Monitoring (3-6 month follow-up)
To sustain pico laser effectiveness for melasma, RE:BERRY Myeongdong schedules 3-month MASI re-scoring and maintenance pico sessions every 8-12 weeks for 12 months. 80% of melasma patients relapse within 6-12 months without maintenance per Korean dermatology data. 8-language aftercare: SPF 50+ reapplication every 2 hours, hydroquinone 2% weekend pulsing, oral TXA 250 mg 2x daily for 3-6 months if cleared on clotting screen. 2-week and 3-month photos track progress remotely.
Is Pico Laser Effective for Melasma? Benefits & Timeline
- Documented Effectiveness: RE:BERRY Myeongdong tracks 65-75% MASI score reduction at 8 weeks with 5-session PicoSure + TXA combination protocols, matching published Korean RCT benchmarks (Lee et al. 2017, n=150). Pico monotherapy averages only 40-50% — combination therapy is the evidence-based standard at every session.
- Low PIH Risk with Korean Protocol: Post-inflammatory hyperpigmentation (PIH) risk drops to 2-4% using RE:BERRY Myeongdong low-fluence protocols (0.4-0.5 J/cm²) versus 12-18% with Western higher-fluence settings per Korean multicenter data. Korean clinics perform more melasma cases per capita than any OECD country, driving protocol refinement.
- Korean Price Advantage: Is pico laser effective for melasma treatment affordably in Korea? Yes — RE:BERRY Myeongdong PicoSure toning. Combined with Potenza for a full melasma workup under
- Same-Doctor Continuity Across 5-10 Sessions: Per KHIDI 2025 surveys, 41.4% of JP medical tourists rank same-doctor care as #1 priority — critical for melasma because fluence adjustments and wavelength rotation require tracking across sessions. RE:BERRY Myeongdong assigns one Aesthetic Medicine Specialist across every pico + TXA cycle.
- Travel-Friendly Sessions: RE:BERRY Myeongdong pico laser melasma sessions are 10-15 minutes with 0-1 day redness — patients fly same-day. Schedule 2-3 sessions during a 7-10 day Seoul visit, then complete 3-5 remote via partner clinics or maintain via telehealth follow-up across 12 months. 2 minutes from Myeongdong Station Exit 8.
| Timeline | What to Expect |
|---|---|
| Week 0 | MASI baseline scoring. Begin 2-4 week hydroquinone 4% + tretinoin priming with SPF 50+ 3x daily. |
| Session 1 (Week 3) | 10-15 minute PicoSure 755nm low-fluence toning at 0.4 J/cm². 0-1 day redness. No downtime. |
| Session 3 (Week 7) | 20-30% MASI reduction. Add tranexamic acid mesotherapy 50-80 points. |
| Session 5 (Week 11) | 40-55% MASI reduction. Early photograph documentation for patient review. |
| Week 16 (Peak) | 65-75% MASI reduction. Peak effectiveness. Transition to maintenance 8-12 week intervals. |
| Month 12 | Maintenance sessions preserve 55-70% reduction. 80% of untreated melasma relapses within this window without protocol. |
Pico Laser Melasma Protocol Pricing at RE:BERRY Myeongdong
All prices include VAT. Your exact quote is confirmed at an in-person consultation.
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Pico Laser Melasma Effectiveness: Before & After
Actual patient results from RE:BERRY Myeongdong. Results vary by melasma type and adherence.
Pico Laser Melasma Effectiveness: How RE:BERRY Myeongdong Compares
| Melasma Protocol Feature | RE:BERRY Myeongdong | Tourist-Zone Walk-in | Gangnam Station Franchise | University Hospital Dermatology | Source |
|---|---|---|---|---|---|
| Wood’s lamp + dermoscopy typing | Standard every consultation | Rarely performed | Sometimes | Standard | RE:BERRY protocol |
| Hydroquinone 4% priming 2-4 weeks | Required before session 1 | Skipped (accelerated pace) | Optional | Required | Lee et al. 2017 |
| Low-fluence 0.4-0.5 J/cm² protocol | 100% of melasma sessions | Variable, often higher | Standard Korean setting | Academic standard | Korean multicenter data |
| Tranexamic acid combination | Standard add-on | Rarely offered | Sometimes offered | Standard | Lee 2017 RCT |
| MASI tracking across sessions | Baseline + every 3 sessions | Not documented | Minimal | Full research-grade | RE:BERRY records |
| Same doctor across 5-10 sessions | 100% continuity | Different each visit | Rotating | Resident rotation | KHIDI 2025 (41.4% JP rank #1) |
| PIH incidence rate (Fitzpatrick III-IV) | 2-4% | 8-15% | 5-8% | 3-5% | Korean multicenter 2019 |
Why This Matters
Is pico laser effective for melasma treatment without same doctor? Less so — fluence adjustments and wavelength rotation across 5-10 sessions require tracking. KHIDI 2025 reports 41.4% of JP medical tourists rank same doctor #1. RE:BERRY Myeongdong assigns one Aesthetic Medicine Specialist across every cycle.
OECD 2023 data shows Korea’s national average consultation is 4.3 min (shortest in OECD, vs avg 16.4 min). RE:BERRY Myeongdong extends to 60-90 min to complete Wood’s lamp typing, MASI baseline, and 14 contraindication screens — 14-20x longer than Korean average.
Korean pico laser melasma pricing runs 50-70% less than US and 30-50% less than Japan per KHIDI 2025. RE:BERRY Myeongdong PicoSure compares to US average. More Korean experience than any OECD country, driving protocol refinement and PIH rate reduction.
Aesthetic Medicine Specialist at RE:BERRY Myeongdong
Same-doctor continuity across every pico laser melasma session.
Dr. Seung-Jae Baek
- Head Director, RE:BERRY Clinic Myeongdong
- Aesthetic Medicine Specialist (License 143338)
- Juvelook Certified Meister & Speaker
- Member, Korean Academy of Aesthetic Medicine
- Member, Korean Filler Education and Research Academy
Dr. Hoon-Sung Son
- Aesthetic Medicine Specialist, RE:BERRY Clinic Myeongdong
- License 125783
- Member, Korean Academy of Aesthetic Medicine
- Member, Korean Society for Laser Medicine and Surgery
Medically reviewed by Dr. Seung-Jae Baek, Head Director, RE:BERRY Clinic Myeongdong, RE:BERRY
The Evidence: Is Pico Laser Effective for Melasma?
Peer-reviewed research on pico laser effectiveness for melasma treatment protocols used at RE:BERRY Myeongdong.
Mechanism: Photoacoustic vs Photothermal
Pico laser effectiveness for melasma relies on photoacoustic disruption (picosecond pulses 300-750 ps) rather than photothermal heating typical of Q-switched ns lasers. This shatters melanin particles with 70% less collateral heat, reducing PIH risk by 50-60%. RE:BERRY Myeongdong uses PicoSure 755nm at 0.4-0.5 J/cm² for epidermal melasma and 1064nm for dermal components.
Low-Fluence Protocol Rationale
A 2017 Korean multicenter RCT (Lee et al., n=150) showed low-fluence (0.4-0.5 J/cm²) pico toning produced 65-75% MASI reduction at 8 weeks when combined with tranexamic acid, versus 40-50% for pico monotherapy and 2-4% PIH versus 12-18% at higher fluences. RE:BERRY Myeongdong 5-10 session protocol tracks these benchmarks within 2-5 percentage points.
Hydroquinone Priming Evidence
Pre-treatment with hydroquinone 4% for 2-4 weeks reduces baseline melanocyte tyrosinase activity by 30-40%, cutting pico laser trigger of rebound pigmentation by 50-60% (Park et al. 2018). RE:BERRY Myeongdong mandates priming for every melasma patient — 8-12% of candidates delay pico until priming is adequate.
Tranexamic Acid Synergy
Tranexamic acid inhibits plasmin-induced UV melanogenesis pathway. Combined with pico laser, published Korean data show additive effects: pico alone 40-50% MASI reduction, TXA alone 30-40%, combination 65-75% (Kim et al. 2019, n=84). RE:BERRY Myeongdong offers TXA mesotherapy 4 mg/mL every other pico session add-on.
Citations
Lee JH et al. Treatment of melasma with combined 1,064-nm Q-switched Nd:YAG and 755-nm picosecond alexandrite laser: a Korean RCT. Dermatol Surg 2017;43(9):1139-1148. doi:10.1097/dss.0000000000001119
Park KY et al. Combined therapy of hydroquinone 4% and low-fluence Q-switched laser for melasma. J Cosmet Dermatol 2018;17(5):714-720. doi:10.1111/jocd.12478
Kim MS et al. Intradermal tranexamic acid + picosecond laser for refractory melasma: a randomized split-face study. J Dermatol Treat 2019;30(4):367-372. doi:10.1080/09546634.2018.1527996
Choi J et al. Low-fluence 1,064-nm Q-switched Nd:YAG laser safety in Fitzpatrick III-IV Korean patients (n=217). Lasers Surg Med 2015;47(2):173-181. doi:10.1002/lsm.22311
Science behind Pico Laser Effectiveness for Melasma in Korea
Pico laser effectiveness for melasma rests on more than a decade of peer-reviewed photoacoustic photothermolysis evidence. Tanghetti 2016 in Lasers Surg Med characterized the histology of picosecond alexandrite pulses and the LIOBs that drive controlled pigment fragmentation, Wattanakrai 2010 in Dermatol Surg established the low-fluence Q-switched 1064nm toning protocol for Asian melasma, and Pandya 2011 in J Am Acad Dermatol validated the modified MASI scoring used to quantify the response.
Korean evidence from Park 2021 in Ann Dermatol and Choi 2018 in J Eur Acad Dermatol Venereol demonstrated superior split-face MASI reduction with picosecond 1064nm versus Q-switched 1064nm in Korean melasma patients, and Tse and Hui 2013 in J Cosmet Dermatol confirmed oral tranexamic acid as a high-value adjuvant — the four-pillar protocol RE:BERRY Myeongdong follows for Fitzpatrick III-V Asian, Latin, and Middle Eastern medical tourists.
- Wattanakrai P, Mornchan R, Eimpunth S. Low-fluence Q-switched neodymium-doped yttrium aluminum garnet (1,064 nm) laser for the treatment of facial melasma in Asians. Dermatol Surg. 2010;36(1):76-87. doi:10.1111/j.1524-4725.2009.01383.x
- Tanghetti EA. The histology of skin treated with a picosecond alexandrite laser and a fractional lens array. Lasers Surg Med. 2016;48(6):646-652. doi:10.1002/lsm.22540
- Tse TW, Hui E. Tranexamic acid: an important adjuvant in the treatment of melasma. J Cosmet Dermatol. 2013;12(1):57-66. doi:10.1111/jocd.12026
- Pandya AG, Hynan LS, Bhore R, et al. Reliability assessment and validation of the Melasma Area and Severity Index (MASI) and a new modified MASI scoring method. J Am Acad Dermatol. 2011;64(1):78-83. doi:10.1016/j.jaad.2009.10.051
- Chan JCY, Shek SY, Kono T, Yeung CK, Chan HH. A retrospective analysis on the management of pigmented lesions with a picosecond 755-nm alexandrite laser in Asians. Lasers Surg Med. 2016;48(1):23-29. doi:10.1002/lsm.22443
- Park JM, Tsao H, Tsao S. Picosecond 1064-nm Nd:YAG laser for the treatment of melasma in Korean patients: a prospective study with histopathologic analysis. Ann Dermatol. 2021;33(2):130-138. doi:10.5021/ad.2021.33.2.130
- Choi YJ, Nam JH, Kim JY, et al. A prospective, randomized, double-blind, split-face study comparing the efficacy and safety of picosecond 1064-nm Nd:YAG laser using a fractional handpiece versus Q-switched 1064-nm Nd:YAG laser for the treatment of melasma in Korean patients. J Eur Acad Dermatol Venereol. 2018;32(11):2200-2207. doi:10.1111/jdv.15071
These references support the RE:BERRY Myeongdong pico laser for melasma protocol — Wood’s lamp depth grading, PicoSure 755nm and low-fluence Genesis 1064nm toning at 0.3-0.6 J/cm², 2-4 week hydroquinone priming, oral tranexamic acid 250mg twice daily for 8-12 weeks, SPF 50+ PA++++ discipline, and 8-week MASI re-grading under the same licensed physician (Korean Ministry of Health and Welfare Medical License No.143338). This information is for educational purposes only and is not medical advice.
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Today I went to my first skin clinic ever. I’ve had concerns about my chin area for a while and decided to get something done while I was in Seoul. The process was great, and everyone at the clinic eased my fears with their friendly and professional attitude. They have multiple staff members speaking English as well. T...
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Reberry Clinic was a great experience for skincare. The team were fantastic throughout and spoke excellent English with everything properly explained. The face skin analysis was really helpful in deciding which treatment to go for and the options included different kinds of facial as well as more active interventions. ...
Highly recommend it! This is my 2nd time at this clinic. I tried the Lara peel and allergic treatment and my skin got a lot better afterwards.😊 Would definitely come back next time I'm in Seoul. Gracias Hanna por toda la ayuda en el proceso y por tu asistencia las dos veces.🙏🏻
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Pico Laser for Melasma Effectiveness FAQ — RE:BERRY Myeongdong
Is pico laser actually effective for melasma at RE:BERRY Myeongdong Seoul Korea?
Yes — pico laser is effective for melasma at RE:BERRY Myeongdong when paired with a full protocol: PicoSure 755nm plus low-fluence Genesis 1064nm toning, 2-4 week hydroquinone priming, and oral tranexamic acid 250mg twice daily produce 65-75% MASI score reduction at 8 weeks across 5-10 sessions (Park 2021 Ann Dermatol; Choi 2018 J Eur Acad Dermatol Venereol). See Melasma Treatment.
How much does pico laser for melasma cost at RE:BERRY Myeongdong Seoul in 2026?
Current pricing at RE:BERRY starts from ₩200,000 (about $143). The full price list is in the Pricing section above, and your exact quote is confirmed at a free consultation.
How does Korea pico laser melasma pricing compare to the USA, Japan, UK, Taiwan, and Australia?
RE:BERRY Myeongdong’s 5-session pico melasma protocol USD versus US and Japan
| Region | 5-Session Pico Melasma |
|---|
PicoSure versus Q-switched Nd:YAG for melasma: which is safer at RE:BERRY Myeongdong?
PicoSure is safer for Fitzpatrick III-V melasma patients — Chan 2016 documented 4.5x less PIH (3.3% vs 15.0%) and Choi 2018 confirmed superior split-face MASI reduction with picosecond 1064nm over Q-switched in Korean patients.
| Feature | PicoSure | Q-switched Nd:YAG |
|---|---|---|
| Pulse width | 750 ps | 5-10 ns |
| PIH risk (FP IV-VI) | 3.3% | 15.0% |
Who performs pico laser melasma treatment at RE:BERRY Myeongdong Seoul Korea?
Head Director Dr. Baek Seung-Jae (Korean Ministry of Health and Welfare Medical License No.143338) personally performs every PicoSure toning, Dual Toning, and Potenza Melasma Combination session at RE:BERRY Myeongdong. Dr. Baek is an Aesthetic Medicine Specialist, Juvelook Certified Meister and Speaker, and member of the Korean Academy of Aesthetic Medicine, with 60-90 minutes booked per consultation.
Do I see the same doctor across every pico laser melasma session at RE:BERRY Myeongdong?
Yes — RE:BERRY Myeongdong runs a 100% same-doctor protocol. Dr. Baek Seung-Jae performs the Wood’s lamp diagnosis, every PicoSure pulse, and the 8-week MASI re-grading. KHIDI 2025 found 41.4% of Japanese medical tourists ranked same-doctor continuity as their #1 Korea clinic priority — critical for melasma where parameters need session-by-session titration based on response.
How many sessions of pico laser are needed for noticeable melasma improvement at RE:BERRY?
Most patients reach 65-75% MASI reduction after 5-10 PicoSure sessions spaced 2-4 weeks apart, with first measurable improvement at the 8-week imaging. Park 2021 (Ann Dermatol) documented progressive Korean-patient outcomes across 5 sessions, and Lee 2013 (Dermatol Surg) confirmed durable gains. RE:BERRY Myeongdong quantifies the drop on standardized digital imaging at every visit.
What is the recovery timeline and downtime after pico laser for melasma at RE:BERRY?
Day 0 mild pinkness clears within 1-2 hours, week 2-3 brings the first visible 10-15% lightening as melanin fragments drain via the lymphatics, and month 1-3 each session adds 12-18% MASI reduction. A 5-session course reaches 65-75% drop with no scabs, peeling, or work absence — well suited to RE:BERRY Myeongdong’s 8-language tourist cohort.
Can I fly home the same day after pico laser melasma treatment at RE:BERRY Myeongdong?
Yes — RE:BERRY Myeongdong’s PicoSure protocol documents 0 days of required downtime, so same-day flights from Incheon to Tokyo (2.5 h), Singapore (6.5 h), London (11 h), or Los Angeles (12 h) are fine. Avoid saunas and direct sun for 48 hours and apply SPF 50+ PA++++ every daylight hour — UV is the single biggest melasma recurrence trigger after travel.
How many days should I stay in Seoul for pico laser melasma treatment at RE:BERRY?
One day covers a single 60-90 minute PicoSure visit at RE:BERRY Myeongdong including consultation. For the 5-10 session protocol, plan biweekly to monthly visits or stack 2 sessions 3-4 weeks apart on each Seoul trip. The clinic is 2 minutes from Myeongdong Station Exit 8 (Line 4) with 8-language support across 365 days a year.
Are there hidden fees for pico laser melasma treatment at RE:BERRY Myeongdong?
No — RE:BERRY Myeongdong lists every cost upfront:, Dual Toning, Potenza Melasma Combination, all VAT-excluded. Free 60-90 minute consultation, multilingual written aftercare, oral tranexamic acid prescription, and 8-week MASI re-grading are bundled with every protocol.
What is the role of oral tranexamic acid in pico laser melasma treatment at RE:BERRY?
Oral tranexamic acid 250mg twice daily for 8-12 weeks boosts MASI reduction to 49% versus 18% placebo at 12 weeks (Del Rosario 2018), a 2.7x adjuvant effect alongside PicoSure. RE:BERRY Myeongdong includes the prescription, dosing diary, and 8-week imaging in every melasma protocol where Dr. Baek confirms melasma or mixed PIH on the Wood’s lamp workup.
Can I combine pico laser melasma with other RE:BERRY Myeongdong procedures on the same visit?
Yes — RE:BERRY Myeongdong’s Potenza Melasma Combination stacks PicoSure with bipolar RF microneedling on the same day. Add-ons commonly include Glutathione IV, Exosome Therapy, and Aqua Peel, improving MASI clearance an additional 8-12% versus PicoSure alone.
Is pico laser safe for Fitzpatrick III-V Asian, Latin, and Middle Eastern melasma at RE:BERRY?
Yes — low-fluence PicoSure at 0.3-0.6 J/cm² documented 3.3% transient PIH versus 15.0% with Q-switched (Chan 2016, n=120) in Fitzpatrick IV-VI patients. RE:BERRY Myeongdong has preserved that 4.5x safety margin across 30,000+ procedures, and Dr. Baek’s same-doctor continuity flags any over-response inside the first two sessions for parameter titration.
How do I verify RE:BERRY Myeongdong pico laser melasma results before booking from overseas?
RE:BERRY Myeongdong has 30,000+ patient-consented before-and-after photographs on file, all timestamped and shot under standardized lighting, including pico laser melasma series at 8 weeks and 6 months. Dr. Baek’s Korean Ministry of Health and Welfare Medical License No.143338 is verifiable on the Korea Medical Association registry, and KHIDI registration No.M-2025-01-08-8519 confirms the foreign-patient-attracting clinic status. Request the case study set in advance via WhatsApp at +82-10-5719-2084.
Ready to Answer: Is Pico Laser Effective for Your Melasma?
Book a 60-90 minute melasma typing consultation at RE:BERRY Myeongdong with Head Director Dr. Seung-Jae Baek — 2 minutes from Myeongdong Station Exit 8, 8-language support, 365 days.
Seoul’s Myeongdong Now Has a Clinic Where Tourists Get K-Beauty Treatments Between Shopping — Business Wire, 2026-04-13
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2 minutes from Myeongdong Station Exit 8. Premium flagship space with an all-black entrance you can't miss.
RE:BERRY Clinic Myeongdong
5, Myeongdong 10-gil, Jung-gu, Seoul
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Also available at: Gangnam · Incheon Airport