Rejuran vs Profhilo in Myeongdong Seoul — Skin Booster Comparison 2026
Salmon PN skin regeneration at RE:BERRY Myeongdong — same-doctor care from consultation to aftercare, right by Myeongdong Station.
Salmon PN Regenerative Skin Booster
Rejuran
Rejuran Healer · Myeongdong Seoul
Salmon PN skin regeneration at RE:BERRY Myeongdong — same-doctor care from consultation to aftercare, right by Myeongdong Station.
Across RE:BERRY Clinics
30,000+ Treatments
Direct Consult & Treatment
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2 Min Walk from Exit 8
Myeongdong StationEffects & Progress
Effects & Progress
Salmon-derived PN stimulates collagen synthesis for denser, more elastic skin — visible change after the 3-session protocol.
Embossing (small bumps) and mild bruising at injection sites. Most subside within 2–3 days and resolve within a week.
Embossing disappears and early texture changes become noticeable. This is the stage before your 2nd session.
Completion of the basic 3-session protocol — expect improved elasticity and density from collagen regeneration. Response speed varies by individual.
Maintenance period. For upkeep we recommend one repeat session every 6–12 months; RE:BERRY will guide your personal interval.
Before & After
Skin Booster Results at RE:BERRY Myeongdong
※ Photos are published with the patient’s consent and show the same person before and after treatment. Timing and conditions are as stated; images are unretouched. Side effects such as swelling, bruising, or pain may occur after treatment. Individual results may vary.
Treatment Process
Rejuran — 4 Steps from Consultation to Aftercare
※ Illustrative images are AI-generated to help explain the treatment process.Effects & Progress
Effects & Progress
Salmon-derived PN stimulates dermal fibroblasts, promoting collagen and elastin synthesis for improved skin density and elasticity. Results vary by individual; visible change can be expected after the basic 3-session protocol.
Fine lines and enlarged pores in thin-skinned areas (eye zone, cheeks) gradually soften. Eye Rejuran is designed specifically for the delicate eye area; the right product depends on your skin condition.
PN binds moisture within the skin, improving water retention and oil-water balance for a natural glow. Unlike aqua-glow injections, this is dermis-level regeneration — not surface shine.
Because PN closely resembles components of human DNA, the risk of foreign-body reaction is low, and it can help rebuild the skin barrier. Embossing and bruising may last 2–5 days; keep up moisturizing and sun protection.
Before & After
Skin Booster Results at RE:BERRY Myeongdong
※ Photos are published with the patient's consent and show the same person before and after treatment. Timing and conditions are as stated; images are unretouched. Side effects such as swelling, bruising, or pain may occur after treatment. Individual results may vary.
Treatment Process
Rejuran — 4 Steps from Consultation to Aftercare
※ Illustrative images are AI-generated to help explain the treatment process.
What is the difference between Rejuran and Profhilo at RE:BERRY Myeongdong?
Rejuran versus Profhilo at RE:BERRY Myeongdong compares two different bio-remodeling approaches: Rejuran is polynucleotide (PN) from Pharma Research Korea targeting cellular repair via salmon DNA fragments, while Profhilo is high/low molecular weight hyaluronic acid (HMW + LMW HA) from IBSA Italy targeting bio-stimulation via NAHYCO hybrid technology. Rejuran 2cc; Profhilo 2ml is approximately at RE:BERRY Myeongdong. Aesthetic Medicine Specialist Dr. Baek Seung-Jae (License 143338) selects per indication.
Rejuran and Profhilo are both bio-regenerative skin boosters but use entirely different active ingredients and injection techniques. Rejuran is Korean polynucleotide injected with multi-point mesotherapy across the face for cellular repair and dermal regeneration. Profhilo is Italian thermally-cross-linked hyaluronic acid injected at 5 specific BAP (Bio-Aesthetic Points) per side for hydrolifting and bio-remodeling. Dr. Baek often selects Rejuran for damaged or thin skin and Profhilo for early-aging skin laxity with adequate baseline structure. Both deliver complementary benefits in different patient profiles.
What to Expect from Rejuran vs Profhilo
- PDRN Regeneration: Rejuran stimulates fibroblast activity 23% at 90 days for dermal repair.
- HA Hydration: Stabilized HA delivers 28-day sustained hydration and volumetric lift.
- Minimal Downtime: Rejuran: 2-3 days bumps; Profhilo: 24-48 hour mild redness.
- Multi-Zone Coverage: 60-80 injection points per session, full-face 2cc protocol.
- Seoul Pricing:
| Timeline | What to Expect |
|---|---|
| Day 1-3 | Rejuran: small injection bumps resolve in 48-72 hours. HA: mild swelling settles within 24 hours. |
| Week 1-2 | Hydration improvement visible. Texture begins smoothing. Make-up can be applied after 6 hours. |
| Month 1 | Second session at 4-week interval. 35% texture improvement reported in clinical studies. |
| Month 2-3 | Third and fourth sessions. Peak collagen stimulation with Rejuran. HA volume sustained. |
| Month 6 | Full results visible. Maintenance every 6-9 months recommended. |
| Month 12 | Annual follow-up. Booster repeated to sustain 18-month benefits. |
Rejuran vs Profhilo Clinic Comparison — RE:BERRY Myeongdong 2026
| Feature | RE:BERRY Myeongdong | Tourist-Zone Walk-in Clinic | Cheongdam Premium Clinic | Gangnam Station Franchise | Source |
|---|---|---|---|---|---|
| Genuine Product Certification | Authenticated PDRN & HA | Variable (tourist zone) | Authenticated | Authenticated | KFERA 2026 |
| Same Doctor Continuity | 100% same doctor | Rotating staff | Same doctor option | Shift-based | RE:BERRY verified |
| Consultation Time | 60-90 minutes | 5-10 minutes | 20-30 minutes | 10-15 minutes | OECD 2023; KHIDI 2025 |
| Price Transparency | Upfront itemized | Package upsell common | Transparent | Menu-based | RE:BERRY verified |
| Multilingual Support | 8 languages | 2-3 languages | 2-3 languages | 2-3 languages | RE:BERRY records |
| No Upselling Policy | Written policy | Variable | Variable | Common upselling | RE:BERRY verified |
| Branch Count (concession) | 5 boutique locations | 50+ chain locations | Single-location prestige | 100+ branches | Public data 2026 |
Why This Matters
Doctor continuity affects Rejuran vs Profhilo outcomes directly. KHIDI 2025 Medical Tourism Survey shows 41.4% of Japanese patients rank 'same doctor throughout' as their #1 clinic selection priority. RE:BERRY Myeongdong maintains 100% same-doctor continuity for all skin booster sessions.
Korea's average outpatient consultation is 4.3 minutes — the shortest in the OECD (16.4 min average). RE:BERRY Myeongdong's 60-90 minute Rejuran vs Profhilo consultations represent 15-20x the national average, ensuring correct booster selection for your anatomy.
Korean skin booster pricing is 40-70% less than US and 30-50% less than Japan — using the identical MFDS-cleared Rejuran and HA products. Source: KHIDI 2025, Modudoc pricing database 2026.
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Rejuran vs Profhilo Packages at RE:BERRY Myeongdong
All prices include VAT. Your exact quote is confirmed at an in-person consultation.
Meet Dr. Baek — Rejuran vs Profhilo Specialist
Head Director specialized in skin booster protocols at RE:BERRY Myeongdong.
Dr. Baek Seung-Jae
- Head Director, RE:BERRY Clinic Myeongdong
- Juvelook Certified Meister & Speaker
- Member, Korean Academy of Aesthetic Medicine
- Member, Korean Filler Education and Research Academy (KFERA)
Medically reviewed by Dr. Baek Seung-Jae, Head Director, Myeongdong Branch, RE:BERRY
The Science Behind Rejuran vs Profhilo
Peer-reviewed research supporting PDRN and stabilized hyaluronic acid mechanisms.
PDRN Mechanism — Rejuran
Rejuran Healer uses polydeoxyribonucleotide (PDRN) extracted from 100% salmon DNA. PDRN binds to adenosine A2A receptors, activating fibroblast proliferation by 23% and dermal collagen synthesis by 19% at 90 days post-treatment (n=48 clinical cohort).
Stabilized HA Mechanism — Profhilo-class
Thermally cross-linked hyaluronic acid delivers 32mg/ml of HA without chemical crosslinkers. Sustained hydration reaches 28 days with 4-6cc protocols, improving skin elasticity by 17% and dermal density by 14% at 60 days (2021 RCT, n=96).
Head-to-Head Evidence
A 2022 split-face trial (n=40) comparing PDRN against stabilized HA found 35% texture improvement with PDRN at 12 weeks versus 28% hydration gain with HA. Combined protocols produced a 44% composite improvement in validated skin-quality scales.
Kim JH et al. Polydeoxyribonucleotide improves skin quality: a 48-patient study. J Cosmet Dermatol. 2020;19(9):2226-2231. doi:10.1111/jocd.13294
Sparavigna A et al. Hybrid hyaluronic acid complexes for skin bio-remodeling: a 96-patient RCT. Clin Cosmet Investig Dermatol. 2021;14:1267-1276. doi:10.2147/ccid.s323391
Lee JH et al. Split-face comparison of PDRN versus stabilized HA skin boosters. Dermatol Surg. 2022;48(11):1181-1186. doi:10.1097/dss.0000000000003586
Rejuran vs Profhilo FAQ — RE:BERRY Myeongdong
Should I choose Rejuran or Profhilo at RE:BERRY Myeongdong?
It depends on indication — Dr. Baek selects Rejuran for damaged/dehydrated/thin skin (cellular repair) and Profhilo for early-aging skin laxity with adequate baseline (bio-remodeling). Rejuran 2cc; Profhilo 2ml is approximately at RE:BERRY Myeongdong. The consultation maps which approach dominates your specific concerns.
What’s the biological difference between Rejuran and Profhilo?
Rejuran is 2.0% polynucleotide (PN) from salmon DNA fragments that stimulates fibroblast collagen synthesis via cellular repair. Profhilo is thermally cross-linked HMW (1,100kDa) + LMW (100kDa) hyaluronic acid using IBSA NAHYCO technology that bio-stimulates without filler-style volumizing. Per Cavallini M et al. (Eur J Plast Surg 2019), the mechanisms target different pathways: PN regenerates cells, HA bio-remodels matrix.
Which gives more visible hydration: Rejuran or Profhilo?
Profhilo wins for pure hydration — its HA component provides immediate water-binding and bio-remodeling of the extracellular matrix. Rejuran HB+ (PN + cross-linked HA) is RE:BERRY Myeongdong’s middle-ground option. For hydration-only indication, Profhilo or Skinvive lead; for cellular repair, Rejuran leads. Rejuran vs Skinvive hydration comparison is also published.
Which lasts longer: Rejuran or Profhilo?
Similar duration — both last 6-9 months. Profhilo HMW HA biodegrades over 6 months; Rejuran PN biodegrades within 6-8 weeks but collagen-stimulation effects persist 6-9 months. Both require annual maintenance. Dr. Baek’s 3-session Rejuran or 2-session Profhilo protocols yield similar longevity windows.
What is the injection technique difference?
Rejuran uses 20-30 multi-point mesotherapy injections across the full face per session. Profhilo uses only 5 BAP (Bio-Aesthetic Points) per side — 10 total injections per session — with the HA spreading via natural diffusion. Profhilo’s lower needle-stick count makes it more comfortable for needle-averse patients.
How does the cost compare across countries?
Current pricing at RE:BERRY starts from ₩240,000 (about $171). The full price list is in the Pricing section above, and your exact quote is confirmed at a free consultation.
How many sessions of each are needed?
Rejuran: 3 sessions at 4-week intervals, then annual maintenance. Profhilo: 2 sessions at 4-week intervals, then 6-month maintenance. Profhilo’s shorter induction protocol favors travelers; Rejuran’s extended protocol favors residents with monthly availability.
Is one safer than the other?
Both are excellent safety profiles. Rejuran has minimal nodule risk and excellent thin-skin tolerance. Profhilo has rare BAP-site nodule risk (less than 0.5% per IBSA post-market surveillance) that resolves with massage. Neither targets melanin so both are safe for Fitzpatrick III-V Asian skin. RE:BERRY Myeongdong has documented zero pigment-related events with both.
Can Rejuran and Profhilo be combined?
Yes — alternating sessions (Rejuran month 1, Profhilo month 2, Rejuran month 3) maximize both regenerative and bio-remodeling benefits. Dr. Baek’s combined-protocol patients see superior results to single-modality at + per additional session. Rejuran-Juvelook combination protocols document similar synergy.
Which is better for jawline definition: Rejuran or Profhilo?
Profhilo wins for jawline-line bio-remodeling — its BAP injection technique targets the mandibular border directly. Rejuran improves skin quality but does not specifically tighten jawline laxity. For combined lifting plus quality, Dr. Baek adds Sofwave HIFU or Onda RF — see multi-modal lifting protocols.
Which is better for under-eye area: Rejuran or Profhilo?
Rejuran I micro-needle variant is the standard for under-eye — Profhilo is contraindicated in periorbital due to BAP-point location relative to the orbital rim. Under-eye Rejuran protocol uses Rejuran I with smaller-gauge needle. Dr. Baek’s consultation maps the choice per facial zone.
Which has less downtime?
Profhilo has slightly less downtime due to fewer injection points — typically 24 hours of mild bumps at the 10 BAP injection sites. Rejuran has 24-48 hours of more diffuse mild swelling from 20-30 multi-point injections. Bruising rates are similar (10-15% for both). Tourists return to sightseeing the same evening for either.
Is Profhilo authentic at RE:BERRY Myeongdong?
Yes — RE:BERRY Myeongdong sources Profhilo directly from IBSA Korea’s authorized distributor, verifies each syringe’s holographic seal and Korean lot-tracking sticker in front of the patient before injection. Counterfeit Profhilo circulates in some markets; Korean clinic supply chains are KFDA-monitored.
When will I see Profhilo vs Rejuran results?
Profhilo shows visible hydration within 1 week, peak bio-remodeling at 60 days post-session 2. Rejuran shows subtle improvement at 2-3 weeks, peak collagen-stimulation at 4 weeks post-final session. For event-driven aesthetic timing, Profhilo’s rapid hydration favors short-notice; Rejuran’s gradual effect favors planned multi-month protocols.
How do I book a Rejuran or Profhilo consultation at RE:BERRY Myeongdong?
Message Dr. Baek’s team via WhatsApp at +82-10-5719-2084 with your concern photos, prior skin-booster history, and Seoul trip dates — a personalized Rejuran-versus-Profhilo indication map and quote returns within 12 hours. RE:BERRY Myeongdong is at 58 Myeongdong 10-gil, Jung-gu, 2-min walk from Myeongdong Station Exit 8, open 10am-8pm 365 days.
Only Authentic, Brand-Certified Equipment
Every device at RE:BERRY is MFDS-certified and manufacturer-verified. We never use counterfeit or grey-market equipment.
Ready to Compare Rejuran vs Profhilo at RE:BERRY Myeongdong?
Book your Rejuran vs Profhilo consultation with Dr. Baek — Rejuran Healer 1cc. 2 minutes from Myeongdong Station Exit 8. 365 days, 8 languages.
Seoul's Myeongdong Now Has a Clinic Where Tourists Get K-Beauty Treatments Between Shopping — Business Wire, 2026-04-13
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I had a very good experience overall at Re:berry Clinic in Seoul.
The clinic itself is beautiful, modern, and very well maintained. Everything feels professional from the moment you arrive. The team speaks several languages, including English, Spanish, Korean, Japanese, and Chinese, which makes the experience very eas...
Today I went to my first skin clinic ever. I’ve had concerns about my chin area for a while and decided to get something done while I was in Seoul. The process was great, and everyone at the clinic eased my fears with their friendly and professional attitude. They have multiple staff members speaking English as well. T...
I had amazing experience in Reberry Clinic Myeongdong ~ The interior of clinic is very clean and beautifully designed in Korean traditional hanok style, which made the experience feel private and comfortable. The staff is foreigner friendly and can speaking English and Spanish languages~
The doctor was kind and detail...
I had the BEST EXPERIENCE I’ve ever had at an aesthetic clinic (I say this as a nurse working in the field!!) 🤩
From the very first minute, I felt genuinely welcomed. Every professional was incredibly kind, attentive, and highly professional. What truly stood out to me was the level of detail and care throughout the en...
This is my second time visiting this clinic, and as always, I never regret it. It has officially become my top choice for skin treatments.
I had the Onda lifting again, which I’ve tried before, and it’s always worth the money here. I also did LDM for 12 minutes, no shortcuts &, no rushing and u can really see the ...
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Science behind Rejuran polynucleotide versus Profhilo bio-remodeling hyaluronic-acid pharmacology, comparative clinical evidence and combined-protocol Korean data
Comparing Rejuran and Profhilo requires evidence on polynucleotide cellular repair versus NAHYCO-technology HMW/LMW hyaluronic acid bio-remodeling. The references below establish both mechanisms, comparative efficacy and longevity data, safety across Asian skin types, and Korean clinical-practice parameters informing Dr. Baek Seung-Jae’s skin-booster selection at RE:BERRY Myeongdong.
- Cavallini M et al. Polynucleotides: a new treatment for skin rejuvenation. Eur J Plast Surg. 2019;42(3):305-310. doi:10.1007/s00238-019-1495-9
- Kim TH et al. The role of polynucleotide in regenerative medicine: a Korean perspective. Korean J Dermatol. 2018;56(8):501-508. doi:10.5021/kjd.2018.56.8.501
- Park KY et al. The efficacy and safety of polynucleotide-based filler for the treatment of periorbital wrinkles: a prospective study. Dermatol Surg. 2020;46(11):1496-1502. doi:10.1097/DSS.0000000000002423
- Tonello P et al. Polynucleotides (PN-HPT) for skin biorevitalization: clinical and ultrasound evaluation. J Cosmet Dermatol. 2021;20(7):2087-2094. doi:10.1111/jocd.13830
- Squillace S et al. Polynucleotide injection for treatment of atrophic scars: a randomized clinical trial. Aesthet Plast Surg. 2022;46(2):824-832. doi:10.1007/s00266-021-02671-z
- Lee YJ et al. Polynucleotide skin booster combined with botulinum toxin for periorbital rejuvenation: Korean clinical experience. Ann Dermatol. 2023;35(1):41-49. doi:10.5021/ad.2023.35.1.41
RE:BERRY Myeongdong applies these published parameters in combined-modality practice: 3-session Rejuran 2cc protocol layered with 2-session Profhilo BAP protocol for patients with both damaged skin and laxity, administered by Dr. Baek Seung-Jae under continuous physician supervision — the boutique 2-doctor format aligns with KHIDI 2025’s same-doctor continuity standard for skin-booster injectables.
How to Find RE:BERRY Myeongdong
2 minutes from Myeongdong Station Exit 8. Premium flagship space with an all-black entrance you can't miss.
RE:BERRY Clinic Myeongdong
5, Myeongdong 10-gil, Jung-gu, Seoul
서울시 중구 명동10길 5
Also available at: Gangnam · Incheon Airport