
Rejuran vs Skinvive in Korea — The Definitive Skin Booster Comparison
Rejuran Healer and Skinvive by Juvederm represent two different philosophies in skin rejuvenation: cellular repair versus deep hydration. RE:BERRY Myeongdong offers both treatments, and our dermatologists will help you understand which approach — or combination — will transform your skin most effectively.
Rejuran or Skinvive — Which Skin Booster Is Better?
Choose Rejuran if you want long-term skin quality improvement through cellular repair — it treats the cause of dull, damaged skin. Choose Skinvive if you want immediate deep hydration and glow. At RE:BERRY Myeongdong, Rejuran Healer 1cc starts at just ₩99,000 for first-time visitors.
Rejuran Healer contains PDRN (Polydeoxyribonucleotide) extracted from salmon DNA. PDRN activates the A2A adenosine receptor on fibroblasts, stimulating cellular repair, collagen synthesis, and anti-inflammatory pathways. It genuinely improves skin structure from the cellular level up. Skinvive by Juvederm uses micro-droplets of modified hyaluronic acid (HA) injected into the dermis. HA is a powerful humectant that attracts and binds water molecules, providing immediate and visible hydration, smoothness, and glow. RE:BERRY Myeongdong dermatologists frequently recommend Rejuran for patients with damaged, scarred, or aging skin, and Skinvive for those seeking an immediate hydration boost before events.
Skin Booster Before-and-After Gallery
Actual patient results from RE:BERRY Myeongdong. Standardized photography with patient consent.
How Skin Booster Treatments Work at RE:BERRY
Both Rejuran and Skinvive are injected by board-certified dermatologists using sterile techniques.
1. Skin Analysis & Consultation
Your dermatologist examines skin quality, hydration levels, texture, scarring, and overall condition. This determines whether Rejuran, Skinvive, or a combination approach is optimal for your specific needs.
2. Treatment Selection & Planning
Based on your skin condition and goals, the doctor selects the appropriate product, volume, and injection depth. Treatment areas are identified — full face, specific zones, or targeted areas.
3. Numbing & Preparation
Topical anesthetic cream is applied for 15-20 minutes. The treatment area is cleaned and prepared for injection.

4. Micro-Injection
Using fine needles or a meso-gun device, micro-droplets are injected into the superficial dermis across the treatment area. Multiple small injections distribute the product evenly for uniform results.
5. Post-Treatment Care
Small bumps at injection sites are normal and flatten within 24-48 hours. Soothing aftercare is applied. Follow-up session is scheduled (typically 2-4 weeks for a series protocol).
Rejuran vs Skinvive — Benefits and Expected Timeline
- Rejuran: Cellular-Level Skin Repair PDRN activates fibroblasts to produce new collagen, elastin, and glycosaminoglycans. It genuinely repairs damaged skin structure rather than just hydrating it. Proven anti-inflammatory benefits help with rosacea, acne scars, and sensitive skin.
- Skinvive: Instant Deep Hydration Modified HA micro-droplets integrate into the dermis and attract water molecules, providing immediate and visible hydration. Skin appears plumper, smoother, and glowing within days.
- Rejuran: Scar & Damage Improvement PDRN’s tissue repair properties make it uniquely effective for improving acne scars, large pores, and sun-damaged skin over a treatment series.
- Skinvive: FDA-Cleared for Skin Quality Skinvive is the first FDA-approved HA product specifically for improving skin quality (smoothness) of the cheeks, offering clinical evidence for its aesthetic benefits.
- Combinable for Maximum Effect Rejuran and Skinvive address different aspects of skin quality. Using both — Rejuran for repair, Skinvive for hydration — can produce comprehensive skin transformation.
| Timeline | What to Expect |
|---|---|
| Day 0 | Treatment completed. Small micro-bumps visible at injection sites. Mild redness normal. |
| Day 1-3 | Micro-bumps flatten and disappear. Skinvive patients notice immediate hydration improvement. Rejuran redness subsides. |
| Week 1 | Skinvive glow is fully visible. Rejuran cellular repair process beginning at the molecular level. |
| Week 2-4 | Rejuran collagen stimulation becomes visible — improved texture, smaller pores, better skin tone. Second session recommended for both treatments. |
| Month 2-3 | After 3-session Rejuran series: significant skin quality improvement. Scars appear softer. Skin is visibly healthier and more resilient. |
| Month 6-9 | Rejuran results maintained for 6-9 months. Skinvive results maintained for 6 months. Maintenance sessions extend results. |
Rejuran vs Skinvive — Complete Feature Comparison
| Feature | Rejuran Healer | Skinvive by Juvederm |
|---|---|---|
| Active Ingredient | PDRN (Polydeoxyribonucleotide) from salmon DNA | Modified Hyaluronic Acid (Vycross technology) |
| Manufacturer | Pharma Research Products (South Korea) | Allergan/AbbVie (USA) |
| Regulatory Status | KFDA (MFDS) approved, widely used across Asia | FDA-approved for improving skin smoothness of cheeks |
| Mechanism of Action | Activates A2A adenosine receptor, stimulates fibroblast proliferation, promotes collagen/elastin synthesis, anti-inflammatory | HA micro-droplets integrate into dermis, attract and bind water molecules for deep hydration |
| Primary Benefit | Skin repair and regeneration at cellular level | Deep hydration and immediate glow |
| Hydration Effect | Moderate — indirect through improved skin structure | Strong — direct HA-mediated water binding |
| Collagen Stimulation | Strong — primary mechanism via PDRN-fibroblast activation | Mild — some collagen stimulation from HA presence |
| Anti-Inflammatory Effect | Yes — clinically proven anti-inflammatory properties | No significant anti-inflammatory effect |
| Scar Improvement | Yes — effective for acne scars, surgical scars, pore reduction | No significant scar improvement |
| Pore Size Reduction | Yes — collagen and elastin production tightens pores | Mild — hydration may temporarily minimize pore appearance |
| Immediate Result Visibility | Gradual — full results develop over 2-4 weeks per session | Immediate — hydration glow visible within days |
| Number of Sessions | 3-4 sessions, 2-4 weeks apart (initial series) | 2-3 sessions, 1 month apart (initial series) |
| Treatment Area | Full face, neck, under-eye, hands, scalp | Cheeks (FDA indication), off-label full face |
| Injection Depth | Superficial dermis (papillary dermis) | Mid-dermis (reticular dermis) |
| Duration of Results | 6-9 months per series | 6 months |
| Ideal Candidate | Damaged skin, acne scars, aging skin, sensitive skin, skin repair needed | Dehydrated skin, dull complexion, pre-event glow, fine lines |
| Pain Level | Mild — topical numbing used, micro-injection technique | Mild — contains lidocaine, micro-injection technique |
| Downtime | 1-3 days of micro-bumps | 1-2 days of micro-bumps |
| Product Range | Rejuran Healer, Rejuran I (under-eye), Rejuran S (scars), Rejuran HB (hydro booster) | Skinvive (single product) |
| RE:BERRY Myeongdong Price | ₩99,000 (1cc, first visit cheek area) | Contact for current pricing |
Skin Booster Pricing at RE:BERRY Myeongdong
April 2026 promotional rates. Tax excluded. All products are genuine and sealed.
Rejuran Healer 1cc (First Visit)
- Rejuran Healer 1cc (cheek area)
- Consultation with dermatologist
- Post-treatment care
Lilied M 5cc + Lilied K 4cc + Dermio
- Lilied M 5cc
- Lilied K 4cc
- Dermio Care 15 min
- Consultation with dermatologist
Rejuran HB+ 4cc + Eye Rejuran + Cryo
- Rejuran HB+ 4cc
- Eye Rejuran 2cc
- Cryotherapy
- Consultation with dermatologist
Board-Certified Skin Rejuvenation Specialists
All skin booster injections at RE:BERRY Myeongdong are performed by board-certified dermatologists with deep expertise in skin quality treatments.

Dr. Baek Seung-Jae
- Board-Certified Dermatologist
- Rejuran Certified Provider
- Skin Booster Expert
- 10+ Years Clinical Experience

Dr. Son Hoon-Sung
- Board-Certified Dermatologist
- Injectable Specialist
- Skin Quality Expert
Medically reviewed by Dr. Baek Seung-Jae, Head Director, Myeongdong Branch, RE:BERRY
PDRN vs Hyaluronic Acid — How Each Transforms Your Skin
Understanding the molecular mechanisms reveals why these two approaches produce different results.
Rejuran’s active ingredient, PDRN (Polydeoxyribonucleotide), consists of DNA fragments extracted from salmon sperm. These fragments are 50-1500 base pairs in length and work primarily by binding to the A2A adenosine receptor on fibroblast cell surfaces. This binding triggers a cascade of intracellular signals that promote: (1) fibroblast proliferation — more cells producing collagen and elastin; (2) increased VEGF (Vascular Endothelial Growth Factor) for improved blood supply to the skin; (3) anti-inflammatory cytokine modulation, reducing chronic skin inflammation; and (4) accelerated wound healing and tissue repair. These mechanisms mean Rejuran doesn’t just improve how skin looks — it fundamentally improves skin structure and health.
Skinvive by Juvederm uses modified hyaluronic acid based on Allergan’s Vycross technology, delivered as micro-droplets into the mid-dermis. HA is a naturally occurring glycosaminoglycan that can bind up to 1,000 times its weight in water. When injected into the dermis, these micro-droplets create a hydration reservoir that attracts and retains water molecules, leading to immediate and visible skin plumping, smoothness, and glow. The modified cross-linking gives Skinvive longer duration than un-crosslinked HA, maintaining hydration for approximately 6 months.
The key distinction is that Rejuran repairs and regenerates skin structure (collagen, elastin, blood vessels), while Skinvive hydrates existing skin structure with HA. For patients with fundamentally healthy but dehydrated skin, Skinvive provides fast, visible improvement. For patients with damaged, scarred, or aging skin that needs structural repair, Rejuran addresses the root cause. At RE:BERRY Myeongdong, we often combine both: Rejuran for cellular repair and Skinvive or Belotero Revive for immediate hydration — addressing both the foundation and the surface.
What Our Patients Say About Skin Boosters
“Rejuran at ₩99,000 for first visit is unbelievable value. After 3 sessions, my acne scars are noticeably flatter and my skin texture is completely different. This is the treatment I tell everyone about.”
“Got Rejuran HB+ with Eye Rejuran before my wedding. The glow was exactly what I wanted. My photographer commented on how my skin looked incredible without filters.”
“I’ve done both Rejuran and Skinvive at different clinics. Rejuran gives better long-term improvement. Skinvive gives better immediate hydration. At RE:BERRY they suggested doing both and my skin has never looked this healthy.”
“The difference between Rejuran in Korea vs what I paid back home in Singapore is staggering. ₩99,000 versus $400 SGD. The quality of treatment at RE:BERRY Myeongdong was outstanding.”
Frequently Asked Questions: Rejuran vs Skinvive
Expert answers from RE:BERRY Myeongdong’s skin booster specialists.
Rejuran contains PDRN (salmon DNA) that repairs skin at the cellular level by stimulating fibroblast activity and collagen production. Skinvive contains hyaluronic acid micro-droplets that hydrate the skin by attracting and binding water. Rejuran repairs; Skinvive hydrates.
Skinvive shows visible hydration improvement within 2-3 days. Rejuran’s structural repair develops gradually over 2-4 weeks per session, with optimal results after a 3-session series.
Rejuran Healer 1cc is ₩99,000 for first-time visitors (cheek area). This is a one-time trial price. Regular pricing and multi-session packages are available — ask during consultation.
Yes. Many patients benefit from combining both: Rejuran for cellular repair and Skinvive for immediate hydration. Your dermatologist can create a protocol using both products, either in the same session or alternating sessions.
Yes. Rejuran’s PDRN is extracted from salmon (Oncorhynchus keta) sperm DNA through a pharmaceutical purification process. The resulting PDRN fragments are biocompatible and have been used safely in millions of treatments.
Seafood allergies are typically triggered by proteins (like tropomyosin), not DNA. PDRN is purified DNA without protein content. However, inform your dermatologist of any allergies during consultation for proper assessment.
A standard initial series is 3-4 sessions, spaced 2-4 weeks apart. This allows cumulative collagen and repair benefits to build. Maintenance sessions every 3-4 months sustain results.
2-3 sessions, approximately 1 month apart, for optimal hydration. Maintenance every 6 months to sustain the glow.
Both treatments involve micro-injections into the dermis. Topical numbing cream is applied before treatment. Most patients rate the discomfort as 2-3 out of 10. Skinvive contains lidocaine for additional comfort.
Small papules (bumps) at injection sites are normal and expected. They are the micro-droplets of product sitting in the superficial dermis. Rejuran bumps typically flatten within 1-3 days; Skinvive bumps within 1-2 days.
Avoid makeup for 6-12 hours after treatment to minimize infection risk. After that, gentle makeup application is fine. Avoid heavy foundation on injection sites for 24 hours.
Rejuran is significantly better for acne scars. Its PDRN activates tissue repair pathways that genuinely remodel scar tissue. Rejuran S is a specialized formulation specifically for scar treatment.
For immediate brightness and glow, Skinvive provides faster visible results. For long-term improvement of dull, damaged skin, Rejuran’s cellular repair produces more fundamental and lasting improvement.
Yes. Rejuran I (eye formula) is specifically designed for the delicate under-eye area. It improves dark circles, fine lines, and crepey skin around the eyes. RE:BERRY Myeongdong offers Eye Rejuran as part of several packages.
Yes. Rejuran has been used in over 10 million treatments across Asia since its introduction. It is KFDA-approved with an excellent safety record when administered by qualified medical professionals.
Yes. Skinvive by Juvederm is FDA-approved and manufactured by Allergan, one of the world’s most trusted aesthetic pharmaceutical companies. It uses well-established hyaluronic acid technology.
Rejuran Healer focuses on skin repair and collagen stimulation (PDRN-centric). Rejuran HB (Hydro Booster) combines PDRN with hyaluronic acid for both repair and hydration in one product — a middle ground between Rejuran Healer and Skinvive.
Pause retinoid use 3-5 days before treatment to reduce skin sensitivity. You can resume retinoids 3-5 days after treatment once injection sites have fully healed.
Avoid direct sun exposure, saunas, swimming pools, and intense exercise for 24-48 hours. Do not massage or press on treated areas. Apply sunscreen diligently.
Yes. Skin boosters are popular among men seeking improved skin quality, texture, and hydration. The treatment is identical and equally effective for male skin.
Both are skin quality treatments but work differently. Profhilo uses stabilized HA for bio-remodeling. Rejuran uses PDRN for cellular repair. Rejuran is generally superior for scar improvement and damaged skin; Profhilo for overall skin laxity.
Rejuran HB combines PDRN repair with HA hydration at Korean pricing. Belotero Revive is another HA-based skin quality option. Your dermatologist can recommend the best option within your budget.
Yes. Skin boosters combine well with lasers (PicoSure, Genesis), RF treatments (Potenza, Thermage), lifting (Ultherapy, Sofwave), and other injectables (Botox, fillers). Your doctor will plan optimal timing.
Contact RE:BERRY Myeongdong via WhatsApp at +82-2-776-2822 for English-language consultation and booking. First visit Rejuran 1cc at ₩99,000 is one of the best introductory offers in Seoul.
The ₩99,000 first visit price for Rejuran 1cc (cheek area) is a one-time trial offer for new patients. Regular and multi-session pricing is available for ongoing treatment.
Yes. Skin booster treatments take 30-45 minutes with no meaningful downtime. Micro-bumps flatten within 1-3 days. RE:BERRY Myeongdong is open 365 days in central Seoul.
Only Authentic, Brand-Certified Equipment
Every device at RE:BERRY is MFDS-certified and manufacturer-verified. We never use counterfeit or grey-market equipment.
Ready for Glass Skin?
Book a free consultation and discover whether Rejuran, Skinvive, or a combination protocol will transform your skin. First visit Rejuran Healer 1cc at just ₩99,000 — one of the best introductory offers in Seoul.
Related Treatments
Book Your Skin Booster Consultation at RE:BERRY Myeongdong
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