Xeomin Botox Treatment in Myeongdong Seoul
Xeomin by Merz Aesthetics is the world’s only complexing-protein-free botulinum toxin. This pharmaceutical-grade purity reduces antibody formation risk and delivers consistent, natural results. Available at RE:BERRY Myeongdong in premium eye rejuvenation packages.
What Is Xeomin?
Xeomin (incobotulinumtoxinA) is a purified botulinum toxin type A manufactured by Merz Aesthetics. It is the only botulinum toxin product that is free of complexing proteins, containing only the active 150 kDa neurotoxin molecule. This pharmaceutical-grade purity means lower immunogenicity and reduced risk of developing resistance over time.
All botulinum toxin products work by temporarily blocking acetylcholine release at the neuromuscular junction, relaxing targeted facial muscles to smooth dynamic wrinkles. Traditional botulinum toxin products (Botox/onabotulinumtoxinA, Dysport/abobotulinumtoxinA) contain complexing proteins that do not contribute to the therapeutic effect but can trigger antibody formation. Xeomin’s XTRACT purification process removes these unnecessary proteins, delivering only the pure active neurotoxin. This makes Xeomin particularly valuable for patients who receive regular botulinum toxin treatments.
Xeomin Before & After
Actual patient results from RE:BERRY Myeongdong.
How Xeomin Treatment Works at RE:BERRY
Four-step protocol for precise, natural-looking botox results.
Facial Muscle Analysis
Dr. Baek assesses your facial muscle activity, expression patterns, and wrinkle depth to design a customized injection plan for natural results.
Injection Point Mapping
Precise injection points marked based on muscle anatomy. For the eye package, areas around crow’s feet, under-eye, and brow are carefully mapped.
Precision Micro-Injection
Xeomin injected using ultrafine needles at precise depths. For the eye package, combined with Eye Oligio 400 shots and Eye Rejuran 2cc for comprehensive periorbital rejuvenation.
Post-Injection Care
Brief observation period. Aftercare instructions provided. Results develop over 3-7 days. No downtime required.
What to Expect from Xeomin Treatment
- Pure Neurotoxin: Zero complexing proteins means lower antibody risk and more consistent results over repeated treatments.
- No Refrigeration Needed: Xeomin’s purity allows room temperature storage, ensuring consistent potency at every clinic.
- Natural Expression: Precise dosing relaxes targeted muscles while preserving natural facial movement and expression.
- FDA-Approved: Approved for glabellar lines, forehead lines, and lateral canthal lines (crow’s feet).
- Quick Treatment: Injection takes only 10-15 minutes. No anesthesia needed in most cases.
- Versatile Applications: Treats wrinkles, jawline slimming, excessive sweating, calf reduction, and more.
| Timeline | What to Expect |
|---|---|
| Day 1-2 | Injection sites may show tiny pinpoint marks. No visible effect yet. Avoid rubbing the area. |
| Day 3-5 | Xeomin begins to take effect. Muscle activity starts to reduce in treated areas. |
| Day 7-14 | Full effect visible. Wrinkles smoothed, jawline slimming begins (if masseter treatment). |
| Month 1-2 | Peak results. Skin appears smoother and more refreshed. Jawline visibly slimmer. |
| Month 3-4 | Effects gradually begin to wear off as nerve function returns. |
| Month 4-6 | Maintenance session recommended. Regular treatments may extend intervals over time. |
Xeomin vs. Other Botulinum Toxin Products
| Feature | Xeomin (Merz) | Botox (Allergan) | Dysport (Galderma) | Nabota (Daewoong) |
|---|---|---|---|---|
| Active Molecule | IncobotulinumtoxinA | OnabotulinumtoxinA | AbobotulinumtoxinA | PrabotulinumtoxinA |
| Complexing Proteins | None (pure) | Present | Present | Present |
| Antibody Risk | Lowest | Standard | Standard | Standard |
| Onset Time | 3-5 days | 3-7 days | 2-5 days | 2-5 days |
| Duration | 3-6 months | 3-6 months | 3-4 months | 3-4 months |
| Storage | Room temperature | Refrigerated | Refrigerated | Refrigerated |
| FDA Status | FDA-Approved | FDA-Approved | FDA-Approved | MFDS-Approved |
| Origin | Germany | USA/Ireland | France/UK | South Korea |
Xeomin Packages at RE:BERRY Myeongdong
All prices exclude VAT. Non-covered medical service.
Eye Rejuvenation Package
- Eye Oligio 400 shots (periorbital tightening)
- Painless Eye Rejuran 2cc (under-eye rejuvenation)
- Xeomin Eye Botox (crow’s feet + periorbital)
- Free consultation with Dr. Baek
- Aftercare instructions in your language
Lip Enhancement + Botox Combo
- Juvederm Lip Filler 1cc
- Korean Premium Mouth Corner Lip Botox
- Precision lip design consultation
- Free consultation with Dr. Baek
- Aftercare instructions in your language
Meet Our Specialists
Board-certified aesthetic physicians with extensive botulinum toxin injection experience at RE:BERRY Myeongdong.
Dr. Baek Seung-Jae
- Head Director, RE:BERRY Clinic Myeongdong
- Juvelook Certified Meister & Speaker
- Member, Korean Academy of Aesthetic Medicine
- Member, Korean Filler Education and Research Academy
Dr. Son Hoon-Sung
- Doctor, RE:BERRY Clinic Myeongdong
- Member, Korean Academy of Aesthetic Medicine
- Member, Korean Society for Laser Medicine and Surgery
- Specialist in botulinum toxin and periorbital treatments
Medically reviewed by Dr. Baek Seung-Jae, Head Director, Myeongdong Branch, RE:BERRY
The Science Behind Xeomin
How Xeomin’s XTRACT purification technology delivers the purest botulinum toxin available.
XTRACT Technology: Pure 150 kDa Neurotoxin
Xeomin’s proprietary XTRACT purification process isolates the active 150 kDa botulinum toxin molecule from all complexing proteins (hemagglutinins and non-hemagglutinins). Traditional botulinum toxin products contain a 900 kDa complex of which only 150 kDa is therapeutically active. The remaining 750 kDa of complexing proteins serve no therapeutic purpose but can trigger immune response.
Immunogenicity and Antibody Resistance
Complexing proteins are foreign to the human body and can stimulate the formation of neutralizing antibodies. These antibodies may reduce treatment effectiveness over time (secondary treatment failure). Xeomin’s protein-free formulation has the lowest theoretical immunogenic potential among all botulinum toxin products, making it the preferred choice for long-term, repeated treatment protocols.
Clinical Evidence
Frevert (2015) demonstrated that Xeomin’s protein-free formulation showed the lowest immunogenic potential in preclinical studies. Benecke et al. (2012) confirmed non-inferiority to onabotulinumtoxinA with comparable efficacy and duration. Kane et al. (2015) showed 95% patient satisfaction with Xeomin for glabellar lines at 120 days in a phase III trial.
References: Fabi SG et al. Dermatol Surg. 2017;43(S1):S109-S117. doi:10.1097/DSS.0000000000000867 | Gold MH et al. J Cosmet Dermatol. 2020;19(2):303-309. doi:10.1111/jocd.13172
What Our Patients Say About Xeomin
“The eye package was the best investment. My crow’s feet are gone, under-eyes look brighter with Rejuran, and the Oligio tightening was the cherry on top. I look 5 years younger.”
“I have been getting botox for years and recently developed resistance. Dr. Baek switched me to Xeomin and the results are back to how they were when I first started. The purity makes a difference.”
“Very natural result. My friends cannot tell I had anything done, they just say I look well-rested. That is exactly what I wanted.”
Frequently Asked Questions About Xeomin
Expert answers from RE:BERRY Myeongdong specialists on Xeomin botulinum toxin treatment.
RE:BERRY Myeongdong offers the Eye Oligio + Eye Rejuran + Xeomin Eye Botox package at ₩1,190,000. Lip Filler + Botox combo at ₩460,000. Individual area treatments available upon consultation. All prices exclude VAT.
Xeomin (incobotulinumtoxinA) by Merz Aesthetics is an FDA-approved, purified botulinum toxin type A. It is the only botox product free of complexing proteins, containing only the active 150 kDa neurotoxin molecule.
Botox (onabotulinumtoxinA) contains a 900 kDa complex with complexing proteins. Xeomin contains only the pure 150 kDa active molecule. This purity reduces the risk of antibody formation and potential treatment resistance over time.
Yes. Clinical studies confirm Xeomin is non-inferior to Botox with comparable efficacy and duration. The active neurotoxin molecule is identical in therapeutic function. Some patients report even better consistency with Xeomin.
Results typically last 3-6 months. Duration depends on the treatment area, dosage, and individual metabolism. Regular treatments may extend the interval over time.
Xeomin begins working in 3-5 days with full effect visible at 7-14 days. Slightly faster onset than some other botulinum toxins due to the absence of complexing proteins.
Ultrafine needles are used and the injection takes only 10-15 minutes. Most patients rate discomfort 1-2 on a 10-point scale. Ice can be applied beforehand for extra comfort.
Forehead lines, glabellar lines (11 lines), crow’s feet, brow lift, bunny lines, lip flip, gummy smile, jawline slimming (masseter), neck bands (platysma), and hyperhidrosis.
A comprehensive periorbital treatment combining Eye Oligio 400 shots (RF tightening), Painless Eye Rejuran 2cc (under-eye skin renewal), and Xeomin Eye Botox (crow’s feet smoothing) at ₩1,190,000.
Yes. Xeomin injected into the masseter muscles causes gradual muscle reduction, slimming the lower face for a V-line appearance. Results develop over 2-4 weeks and last 3-6 months.
No downtime. Tiny injection marks resolve within hours. You can apply makeup and resume normal activities immediately. Avoid lying down for 4 hours after treatment.
Yes, antibody-mediated resistance can occur with repeated botulinum toxin treatments. Xeomin’s complexing-protein-free formulation has the lowest immunogenic potential, reducing this risk.
Yes. Xeomin is FDA-approved, CE-marked, and MFDS-approved. It has been used in over 70 countries with an extensive safety record. Common side effects are limited to temporary injection site reactions.
Yes. Botox treats dynamic wrinkles (from muscle movement) while fillers treat volume loss and static wrinkles. RE:BERRY Myeongdong offers combination packages for comprehensive facial rejuvenation.
Pregnant or breastfeeding women, patients with neuromuscular disorders (myasthenia gravis, Lambert-Eaton syndrome), and those with known allergy to botulinum toxin should not receive treatment.
Every 3-6 months for wrinkle treatment. Jawline slimming may need treatments every 4-6 months initially, with intervals lengthening over time as the muscle reduces.
Absolutely. RE:BERRY Myeongdong is 2 minutes from Myeongdong Station with 8-language support. Treatment takes 10-15 minutes with no downtime — the quickest treatment we offer.
All injections performed by board-certified physicians. Dr. Baek Seung-Jae and Dr. Son Hoon-Sung have extensive experience in precision botulinum toxin injection technique.
Avoid blood thinners (aspirin, ibuprofen, fish oil) for 1 week. No alcohol 24 hours before. Inform your doctor of all medications and supplements.
Do not lie down for 4 hours. Avoid rubbing or massaging the treated area for 24 hours. No intense exercise, saunas, or hot baths for 24 hours. Do not consume excessive alcohol.
A small amount of Xeomin injected along the upper lip border relaxes the orbicularis oris muscle, causing the lip to gently flip outward for a subtly fuller appearance without filler.
Yes. Xeomin is effective for hyperhidrosis (excessive sweating) in the underarms, palms, and feet by blocking the nerve signals that stimulate sweat glands.
Skin botox involves superficial micro-injections of diluted botulinum toxin across the skin surface. It reduces pore size, controls oil production, and creates a smoother, more refined skin texture.
Yes. Xeomin injected into the platysma muscle bands smooths vertical neck bands (turkey neck) and can provide a subtle neck lift effect.
Contact us via WhatsApp at +82-2-776-2822 or book through our website. Same-day consultations available with 8-language support.
No. RE:BERRY physicians use conservative dosing to relax wrinkle-causing muscles while preserving natural facial expression. The goal is refreshed, not frozen.
Only Authentic, Brand-Certified Equipment
Every device at RE:BERRY is MFDS-certified and manufacturer-verified. We never use counterfeit or grey-market equipment.
Ready for Pure Botox with Xeomin?
Book your consultation with Head Director Dr. Baek Seung-Jae at RE:BERRY Myeongdong — 2 minutes from Myeongdong Station.
Book Your Xeomin Consultation
Fill out the form and our multilingual team will confirm within 2 hours via your preferred contact method.
- ✓ Free consultation with Head Director
- ✓ 8-language support (EN, JA, ZH, TH, VI, MN, FA)
- ✓ 2 min from Myeongdong Station (Line 4)
- ✓ No downtime — resume sightseeing immediately
- ✓ Visa / Mastercard accepted
- ✓ Current promotion pricing available