Rejuran HB Hydro Booster in Myeongdong Seoul
Rejuran HB combines the regenerative power of polynucleotides with hyaluronic acid for a dual-action skin booster that hydrates and heals simultaneously. Unlike standalone HA boosters, Rejuran HB rebuilds your skin’s moisture-holding capacity from within. Full package with Eye Rejuran + Cryo at RE:BERRY Myeongdong.
What Is Rejuran HB?
Rejuran HB (Hydro Booster) is an advanced skin booster that combines polynucleotides (PN/PDRN) from purified salmon DNA with non-crosslinked hyaluronic acid (HA). While standard Rejuran Healer focuses on cellular regeneration, Rejuran HB adds an immediate and sustained hydration component — making it ideal for dehydrated, dull, or environmentally stressed skin that needs both repair and deep moisture replenishment.
The ‘HB’ stands for Hydro Booster. The formulation pairs two complementary ingredients: polynucleotides stimulate fibroblast proliferation and endogenous HA production (long-term hydration capacity), while the added hyaluronic acid provides immediate water-binding for instant plumpness and glow. This dual mechanism means Rejuran HB delivers both immediate visible improvement and progressive cellular-level regeneration over weeks.
Rejuran HB Before & After
Actual patient results from RE:BERRY Myeongdong showing deep hydration and skin quality improvement.
How Rejuran HB Works at RE:BERRY
A comprehensive hydration and regeneration protocol with targeted eye treatment.
Hydration Assessment & Consultation
Dr. Baek evaluates your skin’s hydration level, barrier function, elasticity, and transepidermal water loss (TEWL) using specialized diagnostic tools. The optimal Rejuran HB dosage and injection pattern are customized to your dehydration pattern.
Numbing & Preparation
Topical anesthetic cream is applied for 30 minutes. Skin is cleansed and treatment zones are mapped. For the full package, the face and under-eye areas are prepared separately.
Rejuran HB+ & Eye Rejuran Injection
Rejuran HB+ 4cc is injected across the full face using a grid-pattern technique at mid-dermal depth. Eye Rejuran 2cc is then carefully placed in the delicate periorbital area using a specialized technique for under-eye rejuvenation.
Cryotherapy & Aftercare
Cryotherapy session follows to reduce swelling, calm the skin, and enhance product absorption. Cold temperature constricts blood vessels and reduces post-injection bumps. Personalized aftercare plan provided.
What to Expect from Rejuran HB
- Dual Hydration: Immediate hydration from HA plus long-term moisture capacity from PN-stimulated endogenous HA production.
- Skin Regeneration: Polynucleotides activate fibroblast proliferation for collagen, elastin, and barrier repair.
- Under-Eye Renewal: Eye Rejuran targets dark circles, fine lines, and crepey texture in the delicate periorbital area.
- Instant Glow: HA component provides immediate plumpness and luminosity from the first session.
- Barrier Restoration: Strengthens the skin barrier to reduce transepidermal water loss long-term.
- Cryo Recovery: Cryotherapy minimizes downtime and enhances treatment absorption.
| Timeline | What to Expect |
|---|---|
| Day 1-2 | Small bumps at injection sites flatten within 24-48 hours. Cryotherapy reduces initial swelling. |
| Week 1 | Immediate HA hydration effect visible. Skin feels plumper and more supple. |
| Week 2-3 | PN regeneration begins. Skin texture improving. Under-eye area brighter. |
| Month 1 | Collagen synthesis accelerates. Skin elasticity measurably improved. |
| Month 2-3 | Peak results. Skin is deeply hydrated, glowing, and resilient. Under-eye lines softened. |
| Month 6-12 | Results maintained with sessions every 3-6 months. Long-term barrier function improved. |
Rejuran HB vs. Other Hydration Boosters
| Feature | Rejuran HB | Rejuran Healer | Skinvive (HA only) | Profhilo |
|---|---|---|---|---|
| Active Ingredients | PN + HA (dual) | PN only | HA only | High/low MW HA |
| Immediate Hydration | Yes (HA component) | Minimal | ✓ | ✓ |
| Cellular Regeneration | Yes (PN/PDRN) | Yes (PN/PDRN) | No | Indirect |
| Endogenous HA Production | Yes (fibroblast stimulation) | ✓ | No | Mild |
| Anti-Inflammatory | Yes (A2A receptor) | ✓ | No | Mild |
| Best For | Dehydrated + damaged skin | Damaged/aging skin | Dehydrated skin only | Skin laxity |
| Under-Eye Formulation | Yes (Eye Rejuran) | Yes (Eye Rejuran) | No | No |
| Glow Effect | Immediate + progressive | Progressive only | Immediate only | Progressive |
Rejuran HB Packages at RE:BERRY Myeongdong
All prices exclude VAT. Non-covered medical service.
First Visit Rejuran Healer
- Rejuran Healer 1cc (cheek area)
- One-time trial for new patients
- Skin analysis consultation
- Experience the Rejuran difference
Rejuran HB+ Full Package
- Rejuran HB+ 4cc (full face)
- Eye Rejuran 2cc (under-eye area)
- Cryotherapy session
- Full face + eye rejuvenation
- Free consultation with Dr. Baek
- Personalized maintenance plan
Meet Our Rejuran HB Specialists
Board-certified aesthetic physicians with specialized expertise in skin booster injection techniques at RE:BERRY Myeongdong.
Dr. Baek Seung-Jae
- Head Director, RE:BERRY Clinic Myeongdong
- Juvelook Certified Meister & Speaker
- Member, Korean Academy of Aesthetic Medicine
- Member, Korean Filler Education and Research Academy
Dr. Son Hoon-Sung
- Doctor, RE:BERRY Clinic Myeongdong
- Member, Korean Academy of Aesthetic Medicine
- Member, Korean Society for Laser Medicine and Surgery
- Specialist in periorbital rejuvenation
Medically reviewed by Dr. Baek Seung-Jae, Head Director, Myeongdong Branch, RE:BERRY
The Science Behind Rejuran HB
How the PN+HA dual formulation delivers superior hydration and regeneration.
Dual-Action Mechanism: PN + HA Synergy
Rejuran HB’s unique formulation combines two complementary bioactive ingredients. Polynucleotides (PN) from salmon DNA activate adenosine A2A receptors, stimulating fibroblast proliferation and endogenous hyaluronic acid synthase (HAS) expression. Meanwhile, the added non-crosslinked hyaluronic acid provides immediate water-binding capacity (each HA molecule binds up to 1,000x its weight in water), creating both instant and progressive hydration.
Endogenous HA Production vs. Exogenous HA
The key advantage of Rejuran HB over pure HA boosters is that PN stimulates the skin’s own HA production machinery. While injected HA degrades within weeks, PN-stimulated fibroblasts continue producing endogenous HA for months. Cavallini et al. (2021) demonstrated that PN treatment increased skin hydration scores by 33% at 3 months — well beyond the lifespan of any injected HA.
Skin Barrier Function and TEWL Reduction
Dehydrated skin has impaired barrier function, leading to increased transepidermal water loss (TEWL). PN stimulates production of ceramides and other barrier lipids while HA maintains dermal hydration. This dual approach reduces TEWL by 20-40% over the treatment course, creating self-sustaining moisture retention.
Periorbital Application (Eye Rejuran)
The under-eye area has the thinnest skin on the body (0.5mm vs. 2mm elsewhere). Eye Rejuran is specifically formulated with lower viscosity for safe, precise placement in this delicate zone. PN’s anti-inflammatory properties (via A2A-mediated NF-kB suppression) help reduce vascular-type dark circles, while collagen stimulation addresses crepey texture and fine lines.
Cryotherapy Enhancement
Post-injection cryotherapy serves three purposes: (1) vasoconstriction reduces bruising and swelling; (2) cold-induced stress response upregulates heat shock proteins that complement PN-stimulated repair; (3) enhanced lymphatic drainage accelerates recovery. Studies show cryotherapy after injectable treatments reduces recovery time by 30-50%.
References: Kerscher M et al. Skin Pharmacol Physiol. 2020;33(6):320-329. doi:10.1159/000511559 | Lee JH et al. Dermatol Surg. 2016;42(S1):S115-S121. doi:10.1097/DSS.0000000000000751
What Our Patients Say About Rejuran HB
“My skin was chronically dehydrated despite using expensive serums. After the Rejuran HB+ full package, my skin holds moisture on its own for the first time in years. The under-eye area improvement was a bonus I did not expect.”
“I chose Rejuran HB over regular Rejuran because I wanted both hydration and regeneration. The immediate glow after treatment was amazing, and it kept getting better over the next 2 months.”
“The cryotherapy after the injections really helped — almost no bumps or swelling compared to my previous Rejuran treatment at another clinic. Dr. Baek’s technique was noticeably smoother too.”
Frequently Asked Questions About Rejuran HB
Expert answers to common questions about Rejuran HB at RE:BERRY Myeongdong Seoul.
RE:BERRY Myeongdong offers the Rejuran HB+ 4cc + Eye Rejuran 2cc + Cryotherapy package at ₩1,125,000. First-time visitors can try Rejuran Healer 1cc at ₩99,000 to experience the polynucleotide effect. All prices exclude VAT.
Rejuran Healer contains polynucleotides only, focusing on skin regeneration and healing. Rejuran HB adds hyaluronic acid to the PN formula, providing both regeneration and immediate + sustained hydration. HB is ideal for dehydrated skin; Healer is better for primarily damaged skin.
The under-eye area is the thinnest skin on your face and shows dehydration and aging earliest. Eye Rejuran is specifically formulated for this delicate zone, addressing dark circles, fine lines, and crepey texture that regular skincare cannot reach.
Cryotherapy after injection reduces swelling, minimizes bruising risk, and enhances product absorption. Cold temperature constricts blood vessels and activates lymphatic drainage, reducing recovery time by 30-50%.
We recommend 3 sessions of the full package spaced 3-4 weeks apart for optimal results. Some patients achieve satisfactory improvement in 2 sessions. Maintenance every 4-6 months sustains results.
Yes, for most patients. Regular HA boosters provide temporary hydration that fades as the HA degrades. Rejuran HB’s PN component stimulates your skin to produce its own HA, creating self-sustaining hydration that lasts much longer.
Yes. The HA component provides instant plumpness and glow from the first session. Bumps from injection resolve in 24-48 hours, after which the immediate hydration effect is visible. The PN regeneration builds over 4-8 weeks.
With topical numbing cream applied for 30 minutes, pain is minimal — typically 2-3 out of 10. The Eye Rejuran injection uses an ultra-fine needle and gentle technique. Cryotherapy afterwards provides additional soothing.
Minimal. Small bumps at injection sites resolve in 24-48 hours (faster with cryotherapy). Mild redness fades within hours. Most patients apply light makeup the next day.
Yes. Rejuran HB’s anti-inflammatory properties (via A2A receptor pathway) actually help calm sensitive skin. The non-crosslinked HA is biocompatible and well-tolerated. KFDA-approved with an excellent safety record.
Yes. Rejuran HB pairs well with Potenza RF for enhanced collagen stimulation, Glass Skin Treatment for comprehensive rejuvenation, or laser toning for pigmentation correction.
Rejuran HB is ideal for patients with dehydrated skin, dull complexion, early aging signs, sun damage, post-procedure recovery needs, and those whose skin does not retain moisture despite using topical products.
The HA hydration effect lasts 2-4 weeks initially. The PN regeneration benefits (increased endogenous HA production, collagen, barrier function) last 4-6 months. Maintenance sessions prolong benefits.
Yes. Rejuran HB addresses dry skin at the source by restoring the skin’s moisture-holding capacity at the dermal level and repairing barrier function to reduce water loss. Results are far more lasting than topical moisturizers.
Rejuran HB+ is the enhanced version with higher PN concentration for stronger regenerative effect. The ‘+’ indicates premium-grade polynucleotides for improved clinical results.
Absolutely. Rejuran HB is popular among male patients who want healthier, more hydrated skin without obvious cosmetic intervention. The results are natural-looking.
Avoid blood thinners (aspirin, ibuprofen), alcohol, and fish oil supplements for 48 hours before treatment. Arrive with clean skin. Inform your doctor of all medications.
Apply SPF 30+ daily. Do not touch injection sites for 6 hours. Avoid saunas, intense exercise, and alcohol for 24 hours. Use gentle, non-irritating skincare for 2-3 days.
Yes. Rejuran HB is excellent for neck rejuvenation, treating horizontal neck lines and crepey texture. The PN+HA combination is particularly effective for the thin, sun-exposed neck skin.
Extremely low. The salmon DNA is purified to remove all proteins (the cause of fish allergies), leaving only nucleotide fragments. Non-crosslinked HA is naturally biocompatible. Allergic reactions are exceedingly rare.
Profhilo uses high and low molecular weight HA for tissue remodeling. Rejuran HB combines PN (regeneration) with HA (hydration). Rejuran HB is better for skin quality and hydration; Profhilo is better for tissue laxity.
Yes. Many patients try the first-visit Rejuran Healer 1cc at ₩99,000 to experience the polynucleotide effect, then upgrade to the full Rejuran HB+ package for comprehensive treatment.
Our full package uniquely combines Rejuran HB+ 4cc (full face) + Eye Rejuran 2cc (under-eye) + Cryotherapy in a single session. Dr. Baek’s Juvelook Meister expertise ensures precise injection technique for optimal PN distribution.
Yes. RE:BERRY Myeongdong is 2 minutes from Myeongdong Station (Line 4, Exit 8). We offer 8-language support. The full Rejuran HB+ package takes about 60-75 minutes including numbing. Perfect for a visit between shopping.
Yes. The Eye Rejuran 2cc in our package specifically targets dark circles by stimulating collagen (thickening thin under-eye skin), reducing vascular inflammation (addressing purple-type circles), and improving overall periorbital hydration.
Contact us via WhatsApp at +82-2-776-2822, KakaoTalk, LINE, or WeChat. We respond in 8 languages. Walk-ins are welcome at RE:BERRY Myeongdong, open 365 days including holidays.
Only Authentic, Brand-Certified Equipment
Every device at RE:BERRY is MFDS-certified and manufacturer-verified. We never use counterfeit or grey-market equipment.
Ready for Deep Hydration + Regeneration?
Book your Rejuran HB consultation with Dr. Baek Seung-Jae at RE:BERRY Myeongdong — 2 minutes from Myeongdong Station. Experience the PN+HA difference.
Book Your Rejuran HB Consultation
Fill out the form and our multilingual team will confirm within 2 hours via your preferred contact method.
- ✓ Free consultation with Head Director
- ✓ 8-language support (EN, JA, ZH, TH, VI, MN, FA)
- ✓ 2 min from Myeongdong Station (Line 4)
- ✓ No downtime — resume sightseeing immediately
- ✓ Visa / Mastercard accepted
- ✓ Current promotion pricing available