Rejuran i Under-Eye Treatment in Myeongdong Seoul
Target dark circles, fine lines, and under-eye hollowing with Rejuran i — a PDRN formula specifically engineered for the delicate periorbital area. Thinner viscosity and optimized molecular weight for safe, effective eye-area rejuvenation at RE:BERRY Myeongdong.
What Is Rejuran i (Eye Rejuran)?
Rejuran i is a specialized polynucleotide (PDRN) injectable designed exclusively for the periorbital area — the thin, delicate skin around the eyes. Unlike standard Rejuran Healer, Rejuran i has a lower viscosity and optimized molecular weight to safely treat under-eye dark circles, fine lines, crepey texture, and hollowing without lumpiness.
The under-eye area has the thinnest skin on the entire face — approximately 0.5mm compared to 2mm elsewhere. Standard skin boosters and fillers risk visible lumps, Tyndall effect (bluish discoloration), or migration in this delicate zone. Rejuran i was specifically formulated by Pharma Research Products to address these challenges with salmon-derived PDRN (polydeoxyribonucleotide) at a concentration and viscosity calibrated for periorbital tissue. At RE:BERRY Myeongdong, Dr. Seung-Jae Baek combines Eye Rejuran with Eye Oligio (periorbital ultrasound lifting) and targeted botox for a comprehensive eye rejuvenation protocol. The PDRN molecules activate adenosine A2A receptors, stimulating fibroblast activity, increasing collagen type I and III synthesis, and improving microcirculation — all critical mechanisms for reducing under-eye darkness and restoring skin elasticity in this fragile area.
Eye Rejuran Before & After
Actual patient results from RE:BERRY Myeongdong. Under-eye rejuvenation with Rejuran i protocol.
How Eye Rejuran Works at RE:BERRY Myeongdong
Four-step protocol specifically designed for safe, effective periorbital rejuvenation.
Eye Area Assessment & Consultation
Dr. Seung-Jae Baek evaluates your under-eye concerns using magnified examination. He assesses skin thickness, pigmentation depth (epidermal vs. dermal melanin), vascular prominence, volume loss, and fine line severity to determine the optimal injection plan. This detailed assessment takes approximately 15 minutes and determines whether Rejuran i alone or a combination protocol is indicated.
Topical Numbing & Preparation
A specialized numbing cream formulated for the periorbital area is applied for 20-30 minutes. Because the eye area skin is thin and sensitive, RE:BERRY uses a gentler anesthetic concentration that minimizes swelling while ensuring comfort. The area is cleansed with antiseptic solution before injection.
Micro-Injection of Rejuran i
Using ultra-fine 32G needles, the doctor delivers Rejuran i in precise micro-droplets across the infraorbital area. The injection technique varies by concern — serial puncture for fine lines, linear threading for hollowing, and nappage technique for overall skin quality. Total injection volume is typically 1-2cc per session, carefully distributed to avoid product migration.
LED Therapy & Aftercare
Post-injection LED light therapy reduces inflammation and accelerates PDRN absorption. Cold compress application minimizes swelling. You receive detailed aftercare instructions: avoid rubbing the eye area for 24 hours, skip eye makeup for 12 hours, and apply prescribed eye cream. Most patients see immediate hydration with full collagen results developing over 2-4 weeks.
What to Expect from Eye Rejuran Treatment
- Designed for Periorbital Skin: Lower viscosity formula specifically engineered for the 0.5mm-thin under-eye skin — no lump risk.
- Dark Circle Reduction: PDRN improves microcirculation and reduces melanin deposition, addressing both vascular and pigmented dark circles.
- Fine Line Smoothing: Stimulates collagen I and III synthesis in the dermis, plumping crepey skin from within.
- Natural Tissue Regeneration: PDRN activates A2A adenosine receptors for genuine cellular repair rather than temporary filling.
- No Tyndall Effect Risk: Unlike HA fillers, Rejuran i does not cause bluish discoloration under thin eye-area skin.
- Minimal Downtime: Return to normal activities within hours. Mild swelling resolves within 24-48 hours.
| Timeline | What to Expect |
|---|---|
| Day 1-2 | Mild swelling and possible pinpoint bruising around injection sites. Keep head elevated while sleeping. Avoid eye makeup. |
| Week 1 | Swelling fully resolves. Immediate hydration effect visible — under-eye skin feels plumper and smoother. |
| Week 2-3 | PDRN-stimulated collagen synthesis begins. Fine lines start softening as dermal thickness increases. |
| Month 1-2 | Dark circles lighten as microcirculation improves. Under-eye texture becomes noticeably smoother and more resilient. |
| Month 3 | Peak results. Maximum collagen remodeling achieved. Under-eye area appears rested, bright, and rejuvenated. |
| Month 6-9 | Results maintained. Follow-up session recommended to sustain collagen levels and continue improvement. |
Rejuran i vs. Other Under-Eye Treatments
| Feature | Rejuran i (Eye) | Under-Eye Filler (HA) | Eye Oligio | Eye Botox |
|---|---|---|---|---|
| Mechanism | PDRN tissue regeneration | HA volume replacement | Ultrasound collagen lifting | Muscle relaxation |
| Best For | Fine lines + dark circles | Volume loss + hollowing | Skin laxity + tightening | Crow’s feet wrinkles |
| Tyndall Risk | None | Possible | None | None |
| Duration | 6-9 months | 9-12 months | 6-12 months | 3-4 months |
| Downtime | 24-48h mild swelling | 3-5 days bruising possible | Minimal | Minimal |
| Sessions Needed | 2-3 (bi-weekly) | 1 | 1 | 1 (every 3-4 months) |
| Natural Results | Tissue regeneration | Volume addition | Collagen stimulation | Wrinkle relaxation |
| Combinability | Excellent with all | Caution with HA products | Pairs well with Rejuran | Pairs well with Rejuran |
Eye Rejuran Packages at RE:BERRY Myeongdong
All prices exclude VAT. Non-covered medical service. April 2026 promotion pricing.
Complete Eye Rejuvenation Package
- Eye Oligio 400 shots
- Painless Eye Rejuran 2cc
- Xeomin Eye Botox
- Free consultation with Dr. Seung-Jae Baek
- Aftercare in your language
Rejuran HB+ Eye Hydration Package
- Rejuran HB+ 4cc (face + eyes)
- Eye Rejuran 2cc
- Cryotherapy
- Post-treatment care
- 8-language aftercare instructions
Meet Our Eye Rejuvenation Specialists
Aesthetic medicine specialists with extensive periorbital injection experience at RE:BERRY Myeongdong.
Dr. Seung-Jae Baek
- Head Director, RE:BERRY Clinic Myeongdong
- Juvelook Certified Meister & Speaker
- Member, Korean Academy of Aesthetic Medicine
- Member, Korean Filler Education and Research Academy
Dr. Hoon-Sung Son
- Aesthetic Medicine Specialist, RE:BERRY Clinic Myeongdong
- Member, Korean Academy of Aesthetic Medicine
- Member, Korean Society for Laser Medicine and Surgery
Medically reviewed by Dr. Seung-Jae Baek, Head Director, Myeongdong Branch, RE:BERRY
The Science Behind Rejuran i for Under Eyes
Peer-reviewed research supporting PDRN efficacy in periorbital skin rejuvenation.
PDRN and the A2A Adenosine Receptor Pathway
Polydeoxyribonucleotide (PDRN), the active ingredient in Rejuran i, is derived from salmon sperm DNA through a controlled extraction process. PDRN fragments activate the adenosine A2A receptor pathway, which plays a central role in tissue repair and anti-inflammatory signaling. In the periorbital area, this activation stimulates fibroblast proliferation, increases collagen type I and type III production, and enhances vascular endothelial growth factor (VEGF) expression for improved microcirculation. The improved blood flow directly addresses vascular-type dark circles — one of the most common under-eye complaints among patients visiting Korean dermatology clinics.
Why Rejuran i Differs from Standard Rejuran Healer
Standard Rejuran Healer has a higher viscosity designed for the thicker dermis of the cheeks and forehead. Rejuran i uses a modified PDRN formulation with lower molecular weight and reduced viscosity, allowing uniform distribution in the thin 0.5mm periorbital dermis without visible lumping. Kim et al. (2020) demonstrated that optimized PDRN molecular weight significantly influences dermal penetration depth and cellular uptake efficiency, confirming the rationale for Rejuran i’s specialized formulation. This molecular engineering prevents the uneven texture that can occur when standard-viscosity products are injected near the surface of thin skin.
Clinical Evidence for Periorbital PDRN
A prospective study by Yoon et al. (2020) evaluated PDRN injections for periorbital rejuvenation in 42 patients and found statistically significant improvements in skin elasticity (28% increase), wrinkle depth reduction (22%), and patient satisfaction scores at 12 weeks. Under-eye skin thickness increased by a mean of 0.12mm, indicating genuine dermal regeneration rather than temporary swelling. Importantly, no cases of Tyndall effect were reported — a common complication with hyaluronic acid fillers in this thin-skinned area. Separately, Cavallini et al. (2021) confirmed PDRN’s anti-inflammatory properties through reduced expression of pro-inflammatory cytokines (IL-6, TNF-alpha), which contributes to the reduction of periorbital puffiness and swelling commonly seen in fatigued or aging under-eye skin.
Combination Protocol Synergy
RE:BERRY Myeongdong’s Complete Eye Rejuvenation Package combines Rejuran i with Eye Oligio (micro-focused ultrasound) and targeted eye botox for multi-layer treatment. The Oligio stimulates deep collagen contraction for tightening, Rejuran i provides dermal-level PDRN regeneration, and botox relaxes orbicularis oculi muscle contractions that cause dynamic crow’s feet. This three-layer approach addresses structural laxity, skin quality, and muscle-driven wrinkles simultaneously — providing comprehensive results that no single modality can achieve alone.
References: Kim JK et al. Efficacy of Polydeoxyribonucleotide in Skin Rejuvenation. J Cosmet Dermatol. 2020;19(9):2321-2326. doi:10.1111/jocd.13308 | Yoon S et al. Clinical Evaluation of PDRN Injection for Periorbital Rejuvenation. Aesthetic Plast Surg. 2020;44(4):1270-1278. doi:10.1007/s00266-020-01645-1 | Cavallini M et al. Polydeoxyribonucleotide for Skin Rejuvenation: Biological Activity and Clinical Results. Aesthetic Surg J. 2021;41(7):NP974-NP982. doi:10.1093/asj/sjaa406
What Our Patients Say About Eye Rejuran
“My dark circles have been my biggest insecurity for years. After two sessions of Eye Rejuran at RE:BERRY, the skin under my eyes looks brighter and smoother than it has in a decade. People keep asking if I had a great vacation.”
“I was worried about getting injections so close to my eyes, but Dr. Baek was incredibly precise and gentle. The numbing made it painless. The combination with Eye Oligio was exactly what I needed — lifting plus skin quality in one session.”
“I tried under-eye filler at another clinic and got Tyndall effect — a blue tint under my eyes. At RE:BERRY they recommended Rejuran i instead, and the difference is night and day. Natural, smooth, no discoloration.”
Frequently Asked Questions About Rejuran for Under Eyes in Korea
Expert answers about Eye Rejuran i treatment at RE:BERRY Myeongdong Seoul.
RE:BERRY Myeongdong’s Complete Eye Rejuvenation Package (Eye Oligio 400 shots + Eye Rejuran 2cc + Xeomin Eye Botox) is ₩1,190,000. The Rejuran HB+ Eye Hydration Package (Rejuran HB+ 4cc + Eye Rejuran 2cc + Cryotherapy) is ₩1,125,000. All prices exclude VAT.
Eye Rejuran packages at ₩1,125,000-1,190,000 are competitively priced considering they include combination treatments (Oligio + Rejuran + Botox). Standard under-eye HA fillers cost ₩350,000-500,000 per session but carry Tyndall effect risk. Rejuran i offers safer, regenerative results.
Yes. The Complete Eye Rejuvenation Package at ₩1,190,000 bundles three treatments (Oligio + Rejuran + Botox) at significant savings versus individual pricing. The Rejuran HB+ Eye Package at ₩1,125,000 combines full-face and eye treatment with cryotherapy.
For dark circles caused by thin skin or vascular congestion, Rejuran i is superior because it regenerates tissue and improves microcirculation. For dark circles caused by deep hollowing or volume loss, HA fillers may be needed. Dr. Seung-Jae Baek assesses the root cause during consultation to recommend the optimal approach.
Rejuran i has lower viscosity and optimized molecular weight specifically for the thin 0.5mm periorbital skin. Standard Rejuran Healer is designed for thicker facial skin (cheeks, forehead). Using standard Rejuran around the eyes risks visible lumps — Rejuran i eliminates this risk.
No. Tyndall effect (bluish discoloration) occurs when HA filler is placed too superficially in thin skin. Rejuran i contains PDRN, not hyaluronic acid, so there is zero risk of Tyndall effect. This is a key advantage of Rejuran i for the under-eye area.
Yes. You can fly the same day or next day after Eye Rejuran. There are no cabin pressure concerns. Mild swelling peaks at 24-48 hours and resolves naturally. Wear sunglasses to protect the treated area during your flight.
Recovery takes 24-48 hours of mild swelling and possible pinpoint bruising. Most patients return to normal activities the same day. Avoid eye makeup for 12 hours and rubbing the area for 24 hours. Swelling is typically minimal and easily concealed.
Common side effects include mild swelling (24-48 hours), pinpoint bruising (resolves in 3-5 days), and slight tenderness. Serious complications are extremely rare when performed by experienced doctors using the proper Rejuran i formulation.
Results from Eye Rejuran last approximately 6-9 months. PDRN stimulates genuine collagen regeneration that gradually improves over 2-4 weeks and sustains for several months. A maintenance session every 6-9 months keeps under-eye skin in optimal condition.
Immediate hydration effect is visible within 24-48 hours once swelling resolves. Collagen remodeling produces progressive improvement over 2-4 weeks. Peak results for dark circles and fine lines appear at 6-8 weeks post-treatment.
RE:BERRY recommends 2-3 sessions spaced 2-3 weeks apart for optimal under-eye results. Each session builds cumulative collagen and improves microcirculation further. Single sessions provide visible improvement, but multiple sessions deliver superior, longer-lasting outcomes.
Eye Rejuran takes approximately 45-60 minutes including numbing time. You need only 1 day in Seoul for the treatment. For a 2-3 session protocol, plan visits 2-3 weeks apart or combine the first session with other treatments during your trip.
Appointments are recommended to ensure the doctor allocates sufficient time for the detailed periorbital injection technique. Contact RE:BERRY Myeongdong via WhatsApp (+82-2-2088-7070) or LINE for convenient scheduling, often available same-day or next-day.
Yes. RE:BERRY Myeongdong supports 8 languages including English, Japanese, Chinese (Simplified/Traditional), Thai, Vietnamese, Mongolian, and Farsi. Your consultation, procedure explanation, and aftercare are fully translated.
Topical numbing cream is applied for 20-30 minutes before injection. Most patients rate the discomfort at 2-3 out of 10 with numbing. Ultra-fine 32G needles are used for the periorbital area to minimize pain. The entire injection process takes 15-20 minutes.
Typically 0.5-1cc per eye (1-2cc total for both eyes). The exact amount depends on the severity of your under-eye concerns and the treatment area. Dr. Seung-Jae Baek customizes the volume during consultation to avoid overfilling.
Rejuran i improves skin quality around the entire periorbital area including crow’s feet. However, for dynamic crow’s feet caused by muscle contraction, combining Rejuran i with eye botox is more effective — which is why RE:BERRY’s Complete Package includes both.
Yes. Rejuran i was specifically developed for periorbital use with a formulation optimized for thin skin. The PDRN is biocompatible (salmon DNA-derived), non-cytotoxic, and does not migrate. Injections are performed in the infraorbital area, not near the eyeball.
Yes. RE:BERRY’s most popular combination is Eye Oligio (ultrasound lifting) + Eye Rejuran (PDRN regeneration) + Eye Botox (wrinkle relaxation) at ₩1,190,000. This multi-layer protocol addresses laxity, skin quality, and dynamic wrinkles simultaneously.
Rejuran i improves skin thickness and elasticity, which can moderately reduce the appearance of mild under-eye bags caused by thin, crepey skin. For pronounced fat herniation (bulging fat pads), surgical blepharoplasty may be more appropriate. Dr. Baek will assess during consultation.
Yes. RE:BERRY Myeongdong uses genuine Rejuran products from Pharma Research Products (the manufacturer). Dr. Seung-Jae Baek is a certified Juvelook Meister with extensive injectable experience. All products are verified authentic with serial numbers.
Yes. All before-and-after images are from actual RE:BERRY Myeongdong patients who provided informed consent. Photos are captured under standardized clinical lighting at consistent angles to accurately represent treatment outcomes.
RE:BERRY offers comprehensive eye rejuvenation packages combining Eye Rejuran with Oligio lifting and targeted botox — not just standalone injections. Dr. Seung-Jae Baek’s injection precision, combined with 8-language support and transparent pricing, makes RE:BERRY the preferred choice for international patients.
RE:BERRY’s three-layer approach (ultrasound + PDRN + muscle relaxation) treats the root causes of under-eye aging simultaneously rather than addressing just one symptom. The Complete Eye Rejuvenation Package at ₩1,190,000 delivers multi-dimensional results in a single visit.
Absolutely. The Rejuran HB+ Eye Package at ₩1,125,000 includes both full-face Rejuran HB+ 4cc and Eye Rejuran 2cc plus cryotherapy. This allows comprehensive facial and periorbital rejuvenation in one session — ideal for travelers with limited time in Seoul.
Only Authentic, Brand-Certified Equipment
Every device at RE:BERRY is MFDS-certified and manufacturer-verified. We never use counterfeit or grey-market equipment.
Ready to Rejuvenate Your Under-Eye Area?
Book your Eye Rejuran consultation with Head Director Dr. Seung-Jae Baek at RE:BERRY Myeongdong — 2 minutes from Myeongdong Station Exit 8. Open 365 days, 10 AM to 8 PM.
Book Your Eye Rejuran Consultation
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- ✓ Free consultation with Head Director
- ✓ 8-language support (EN, JA, ZH, TH, VI, MN, FA)
- ✓ 2 min from Myeongdong Station (Line 4)
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- ✓ Current promotion pricing available