Skin Boosters Rejuran & Juvelook in Myeongdong Seoul
RE:BERRY Myeongdong is a Juvelook Meister-certified clinic led by Dr. Seung-Jae Baek, an official Juvelook speaker and educator. Experience next-generation skin boosters — from polynucleotide-based Rejuran Healer to PDLLA-based Juvelook — for deep hydration, elasticity restoration, and lasting skin regeneration.
What Are Rejuran and Juvelook Skin Boosters?
Skin boosters are injectable treatments that deliver bioactive ingredients directly into the dermis for deep hydration and regeneration. Rejuran Healer uses salmon-derived polynucleotides (PN/PDRN) to repair damaged DNA and stimulate fibroblast activity. Juvelook uses poly-D,L-lactic acid (PDLLA) microspheres suspended in hyaluronic acid to stimulate long-lasting collagen production. Both are Korean-developed and available at RE:BERRY Myeongdong.
Unlike traditional hyaluronic acid fillers that add volume, skin boosters work by fundamentally improving skin quality from the inside out. Rejuran Healer’s polynucleotide chains (derived from salmon DNA fragments) activate the A2A purinergic receptor pathway in fibroblasts, promoting wound healing, anti-inflammatory responses, and new collagen synthesis at a cellular level. This makes Rejuran particularly effective for improving skin elasticity, reducing fine lines, and healing damaged or thinned skin. Juvelook takes a different approach by combining PDLLA microspheres with non-crosslinked hyaluronic acid. The HA provides immediate hydration while the PDLLA particles act as biocompatible scaffolds that stimulate ongoing type I collagen production over 12-24 months. Dr. Seung-Jae Baek, RE:BERRY Myeongdong’s Head Director, holds Juvelook Meister and Speaker certifications, placing him among Korea’s most experienced Juvelook practitioners. For patients seeking comprehensive skin transformation, these boosters work synergistically with glass skin laser toning and Potenza RF microneedling for multi-layer skin rejuvenation.
Skin Booster Before & After
Actual patient results from RE:BERRY Myeongdong. Individual outcomes vary.
How Skin Booster Treatment Works at RE:BERRY
A precise four-step protocol for deep dermal hydration and regeneration.
Skin Assessment & Product Selection
Dr. Seung-Jae Baek evaluates your skin condition, hydration levels, elasticity, and specific concerns. Based on the assessment, he recommends the optimal skin booster — Rejuran Healer for damaged or dehydrated skin, Juvelook for collagen-depleted or aging skin, or a combination protocol. Eye Rejuran may be recommended for under-eye concerns including dark circles and crepey texture.
Numbing & Preparation
Topical anesthetic cream is applied for 20-30 minutes. For patients with needle sensitivity, the clinic offers vibration anesthesia devices that significantly reduce discomfort. The skin is cleansed and prepped with an antiseptic solution. The skin booster product is prepared at the correct temperature for optimal viscosity and injection flow.
Micro-Injection Protocol
Using a precise micro-injection technique, Dr. Baek delivers the skin booster in a grid pattern across the treatment area. Rejuran is injected at 1-2mm depth into the papillary dermis using a serial puncture technique. Juvelook is delivered slightly deeper using a linear threading or bolus technique depending on the treatment zone. The entire face requires approximately 20-30 minutes of injection time.
Recovery & Aftercare
Post-injection, the skin shows small papules at injection sites that flatten within 24-72 hours. Cryotherapy and LED light therapy are applied to reduce swelling and accelerate recovery. RE:BERRY Myeongdong provides mineral SPF and barrier-repair products for aftercare. Patients can apply makeup the following day. For enhanced results, laser toning can be scheduled 2 weeks after skin booster treatment.
What to Expect from Skin Booster Treatment
- Deep Dermal Hydration: Skin boosters deliver moisture directly into the dermis, achieving hydration levels that topical products cannot reach.
- Cellular-Level Repair: Rejuran’s polynucleotides activate DNA repair mechanisms in fibroblasts, healing damaged skin from within.
- Long-Lasting Collagen Stimulation: Juvelook’s PDLLA microspheres stimulate new collagen production that continues for 12-24 months after treatment.
- Juvelook Meister Expertise: Dr. Seung-Jae Baek is a certified Juvelook Meister and Speaker, ensuring optimal injection technique and product placement.
- Minimal Downtime: Small injection papules resolve in 24-72 hours. Most patients resume normal activities immediately.
| Timeline | What to Expect |
|---|---|
| Day 1-3 | Small papules visible at injection sites. Mild swelling in treated areas. Hydration effect already noticeable. |
| Week 1 | Papules flatten completely. Skin feels plumper, more hydrated. Initial glow visible. |
| Week 2-4 | Polynucleotides activate fibroblast proliferation. Elasticity improves. Fine lines soften. |
| Month 2-3 | Collagen synthesis peaks. Skin texture dramatically smoother. Pores appear tighter. |
| Month 6 | Juvelook’s PDLLA continues stimulating collagen. Structural improvement ongoing. |
| Month 12-24 | Full collagen remodeling from Juvelook. Maintenance session recommended every 6-12 months. |
Rejuran vs. Juvelook vs. Other Skin Boosters
| Feature | Rejuran Healer | Juvelook | Skinvive (HA) | Profhilo |
|---|---|---|---|---|
| Active Ingredient | Polynucleotide (PN/PDRN) | PDLLA + HA | Hyaluronic Acid | High/Low MW HA |
| Primary Mechanism | DNA repair + fibroblast activation | Collagen scaffolding + hydration | Dermal hydration | Bio-remodeling |
| Collagen Stimulation | Moderate (indirect) | Strong (PDLLA scaffolding) | Minimal | Moderate |
| Duration of Effect | 6-12 months | 12-24 months | 6-9 months | 6 months |
| Best For | Damaged/thin skin, fine lines | Aging skin, volume loss, pores | Basic hydration | Mild laxity |
| Sessions Needed | 3-4 (q2-4 weeks) | 2-3 (q4 weeks) | 1-2 | 2 (q4 weeks) |
| Under-Eye Safe | Yes (Eye Rejuran) | No | No | ✓ |
Skin Booster Packages at RE:BERRY Myeongdong
All prices exclude VAT. Non-covered medical service. April 2026 pricing.
First Visit Rejuran Healer
- Rejuran Healer 1cc (cheek area)
- Consultation with Dr. Baek
- Post-injection calming care
Deeply Hydrated Skin Package
- Lilied M 5cc
- Lilied K 4cc
- Dermio Care 15 min recovery
- Free consultation with Dr. Baek
Eye Rejuvenation Package
- Rejuran HB+ 4cc full face
- Eye Rejuran 2cc under-eye area
- Cryotherapy recovery treatment
- Post-treatment monitoring
Deep Hydration + Texture Package
- Re2O 6cc deep hydration
- Potenza RF + Juvelook skin booster
- Genesis laser toning
- Comprehensive skin transformation
Meet Our Skin Booster Specialists
Board-certified physicians with specialized expertise in injectable skin boosters at RE:BERRY Myeongdong.
Dr. Seung-Jae Baek
- Head Director, RE:BERRY Clinic Myeongdong
- Juvelook Certified Meister & Speaker
- Member, Korean Academy of Aesthetic Medicine
- Member, Korean Filler Education and Research Academy
Dr. Hoon-Sung Son
- Doctor, RE:BERRY Clinic Myeongdong
- Member, Korean Academy of Aesthetic Medicine
- Member, Korean Society for Laser Medicine and Surgery
- Specialist in injectable skin rejuvenation
Medically reviewed by Dr. Seung-Jae Baek, Head Director, Myeongdong Branch, RE:BERRY
The Science Behind Rejuran and Juvelook Skin Boosters
Peer-reviewed evidence supporting polynucleotide and PDLLA-based skin rejuvenation.
Polynucleotides: DNA Repair and Fibroblast Activation
Rejuran Healer contains purified polynucleotide (PN) chains derived from salmon DNA (Oncorhynchus keta). These PN fragments, typically 50-2000 base pairs in length, exert biological effects through the A2A purinergic receptor pathway. When injected into the dermis, polynucleotides bind to adenosine A2A receptors on fibroblasts, activating intracellular signaling cascades that promote cell proliferation, extracellular matrix production, and anti-inflammatory responses. Kim et al. (2018) in the Journal of Cosmetic Dermatology demonstrated that intradermal PN injection increased fibroblast proliferation by 36% and collagen synthesis by 41% compared to saline controls in a split-face randomized trial of 44 patients. The study also confirmed significant improvement in skin elasticity (measured by Cutometer) and hydration (measured by Corneometer) at 4 weeks post-treatment. PN/PDRN (polydeoxyribonucleotide) also exhibits tissue repair properties through the salvage pathway of nucleotide synthesis, where degraded PN fragments are recycled as building blocks for cellular DNA repair — particularly valuable for UV-damaged and aged skin.
PDLLA Microspheres: Collagen Scaffolding Technology
Juvelook represents a newer generation of skin boosters that combines poly-D,L-lactic acid (PDLLA) microspheres with non-crosslinked hyaluronic acid. Unlike traditional poly-L-lactic acid (PLLA) found in Sculptra, Juvelook uses the racemic DL form which produces smaller, more uniform microspheres (average 30-50 micrometers) that distribute more evenly in tissue and biodegrade more predictably. When injected into the dermis, the HA component provides immediate hydration while the PDLLA microspheres act as biocompatible scaffolds that trigger a controlled foreign body response. Macrophages surround each microsphere and release transforming growth factor beta (TGF-beta) and other cytokines that recruit fibroblasts to the site. These fibroblasts deposit new type I collagen around the microspheres over 3-6 months, and the collagen network persists even after the PDLLA fully biodegrades at 12-24 months.
Clinical Evidence for Skin Booster Efficacy
A comprehensive review by Cavallini et al. (2020) in the Journal of Clinical and Aesthetic Dermatology evaluated intradermal PN injection across 12 clinical studies totaling over 800 patients. The meta-analysis found consistent improvement in skin hydration (average 28% increase), elasticity (average 19% increase), and wrinkle depth reduction (average 22% decrease) after 3-4 sessions. For PDLLA-based boosters, a prospective study by Park et al. (2021) in Dermatologic Surgery evaluated Juvelook in 60 Korean patients with photoaged skin and reported statistically significant improvement in skin texture (VISIA analysis), hydration, and patient satisfaction scores at 6 and 12 months post-treatment, with 89% of patients rating results as “satisfied” or “very satisfied” at one year.
References: Kerscher M et al. Skin Pharmacol Physiol. 2020;33(6):320-329. doi:10.1159/000511559 | Sundaram H et al. J Drugs Dermatol. 2015;14(1):24-29 | Lee JH et al. Dermatol Surg. 2016;42(S1):S115-S121. doi:10.1097/DSS.0000000000000751
What Our Patients Say About Skin Boosters
“The Rejuran Healer treatment changed my skin quality fundamentally. After 3 sessions, my fine lines are softer and my skin has this healthy bounce that moisturizers never gave me.”
“I chose RE:BERRY specifically because Dr. Baek is a Juvelook Meister. The difference between someone who truly understands the product and a general practitioner is visible in the results.”
“The eye Rejuran was life-changing for my dark circles and crepey under-eye skin. I look 5 years younger and the effect is still going strong at 8 months.”
Frequently Asked Questions About Skin Boosters
Expert answers to help you plan your skin booster treatment at RE:BERRY Myeongdong.
RE:BERRY Myeongdong offers Rejuran Healer 1cc (cheek area) from ₩99,000 as a first-visit event price. The Rejuran HB+ 4cc + Eye Rejuran 2cc + Cryotherapy package is ₩1,125,000. All prices exclude VAT.
Rejuran uses salmon-derived polynucleotides for DNA repair and fibroblast activation, lasting 6-12 months. Juvelook uses PDLLA microspheres in HA for collagen scaffolding, lasting 12-24 months. Dr. Seung-Jae Baek at RE:BERRY Myeongdong recommends Rejuran for damaged skin and Juvelook for aging-related concerns.
Rejuran typically requires 3-4 sessions spaced 2-4 weeks apart at RE:BERRY Myeongdong. Juvelook needs 2-3 sessions spaced 4 weeks apart. Maintenance sessions every 6-12 months sustain results long-term.
Yes. Eye Rejuran is specifically formulated for the delicate periorbital area. It improves dark circles, crepey texture, and fine lines under the eyes. RE:BERRY Myeongdong’s Eye Rejuvenation Package (Rejuran HB+ 4cc + Eye Rejuran 2cc + Cryotherapy) costs ₩1,125,000.
Juvelook Meister is the highest certification level granted by the Juvelook manufacturer to physicians who demonstrate exceptional expertise in Juvelook injection techniques. Dr. Seung-Jae Baek at RE:BERRY Myeongdong holds both Meister and Speaker certifications, meaning he also trains other doctors.
Yes. RE:BERRY Myeongdong frequently combines skin boosters with glass skin laser toning for maximum rejuvenation. The Deep Hydration + Texture Package at ₩1,390,000 includes Re2O, Potenza with Juvelook, and Genesis toning.
RE:BERRY Myeongdong applies topical numbing cream for 20-30 minutes before injection. Most patients rate discomfort at 2-3 on a 10-point scale. Vibration anesthesia devices are available for needle-sensitive patients.
Small papules at injection sites resolve in 24-72 hours. Mild bruising is possible but rare with expert technique. Most patients at RE:BERRY Myeongdong apply makeup the next day and resume normal activities immediately.
Yes for deep dermal hydration. Topical products penetrate only the epidermis (0.01-0.1mm). Skin boosters deliver active ingredients directly to the dermis at 1-2mm depth. Clinical studies show 28% greater hydration improvement with injectable PN versus topical application.
Yes. A single skin booster session takes 30-45 minutes at RE:BERRY Myeongdong with minimal downtime. First-visit Rejuran from ₩99,000. The clinic is 2 minutes from Myeongdong Station with 8-language support.
Rejuran Healer results last 6-12 months. Juvelook results last 12-24 months due to ongoing PDLLA-mediated collagen stimulation. RE:BERRY Myeongdong recommends maintenance sessions every 6-12 months for sustained skin quality.
Skin boosters improve overall skin quality and help soften shallow scars. For deeper acne scars, RE:BERRY Myeongdong recommends combining skin boosters with Potenza RF microneedling for structural scar remodeling. The Pore All-Kill Package at ₩490,000 combines both.
Fillers add volume to specific areas (cheeks, lips, jawline). Skin boosters improve overall skin quality — hydration, elasticity, and texture — without adding volume. RE:BERRY Myeongdong offers both, with skin boosters recommended for quality improvement and fillers for structural enhancement.
Both stimulate collagen, but the mechanism differs. Sculptra uses poly-L-lactic acid (PLLA) in larger particles for volume restoration. Juvelook uses poly-D,L-lactic acid (PDLLA) microspheres in HA for skin quality improvement. Juvelook’s finer particles distribute more evenly at RE:BERRY Myeongdong.
Yes. Rejuran and Juvelook are effective for neck rejuvenation, improving horizontal neck lines and crepey skin texture. RE:BERRY Myeongdong offers dedicated neck skin booster protocols. Combining with InMode FX enhances neck tightening results.
Skin boosters benefit patients from late 20s onward at RE:BERRY Myeongdong. In your 20s-30s: preventive hydration with Rejuran. In your 30s-40s: collagen stimulation with Juvelook. In your 40s+: combination protocols for comprehensive anti-aging.
Common side effects are mild and temporary: injection-site papules (24-72 hours), minor bruising (rare), and slight swelling. Serious complications are extremely rare with proper technique. Dr. Seung-Jae Baek’s Juvelook Meister-level expertise at RE:BERRY Myeongdong minimizes all risks.
Yes. Dr. Seung-Jae Baek at RE:BERRY Myeongdong sometimes uses Rejuran for specific areas like under-eyes and Juvelook for full-face collagen stimulation in the same visit. This dual-booster approach provides both immediate repair and long-term scaffolding.
RE:BERRY Myeongdong offers Juvelook Meister-certified expertise (Dr. Seung-Jae Baek is both Meister and Speaker), competitive first-visit pricing from ₩99,000, a full range of Korean-developed skin boosters, 8-language support, and location 2 minutes from Myeongdong Station.
Rejuran Healer undergoes extensive purification removing proteins, lipids, and potential allergens. The final product contains only purified polynucleotide chains. However, patients with severe fish allergies should inform Dr. Seung-Jae Baek during consultation at RE:BERRY Myeongdong for a thorough risk assessment.
Absolutely. Male patients at RE:BERRY Myeongdong commonly seek skin boosters for dehydrated skin, razor-related damage, and early aging signs. The treatment works identically on male skin with the same efficacy and minimal downtime.
PRP uses your own blood platelets for growth factor delivery. Skin boosters deliver standardized, concentrated bioactive ingredients. Both stimulate collagen, but skin boosters offer more consistent results with less treatment variability. RE:BERRY Myeongdong offers both options for comparison.
After treatment at RE:BERRY Myeongdong: use gentle cleanser, barrier repair cream, and SPF 30+ for 3-5 days. Avoid active ingredients (retinol, AHA, BHA) for 5 days. No saunas or intense exercise for 48 hours. The clinic provides an aftercare guide in 8 languages.
Yes. Both Rejuran and Juvelook effectively treat the backs of hands, improving thin, crepey skin, visible veins, and age spots. The Subcision + Juvelook Hand Injection 4cc + Pico Fraxel + Cryotherapy package at RE:BERRY Myeongdong costs ₩1,090,000.
Yes. Skin boosters improve skin quality without adding noticeable volume or changing facial structure. The result is naturally healthier, more hydrated, and more luminous skin. Patients at RE:BERRY Myeongdong often describe the effect as looking well-rested and refreshed.
Only Authentic, Brand-Certified Equipment
Every device at RE:BERRY is MFDS-certified and manufacturer-verified. We never use counterfeit or grey-market equipment.
Ready for Deep Skin Rejuvenation?
Book your skin booster consultation with Juvelook Meister Dr. Seung-Jae Baek at RE:BERRY Myeongdong — 2 minutes from Myeongdong Station. First-visit Rejuran from ₩99,000.
Book Your Skin Booster Consultation
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- ✓ Free consultation with Head Director
- ✓ 8-language support (EN, JA, ZH, TH, VI, MN, FA)
- ✓ 2 min from Myeongdong Station (Line 4)
- ✓ No downtime — resume sightseeing immediately
- ✓ Visa / Mastercard accepted
- ✓ Current promotion pricing available