Sculptra vs Juvederm vs Radiesse: Which Filler Is Best?

Choosing the right dermal filler can feel overwhelming. With dozens of products on the market, how do you know which one is right for your face? The answer depends on your goals, the treatment area, your age, and how long you want the results to last. In this guide, we compare three of the most popular filler categories — Sculptra, Juvederm, and Radiesse — so you can make an informed decision before your visit to RE:BERRY Clinic Myeongdong.

Understanding the Three Categories

These three fillers represent fundamentally different approaches to facial rejuvenation:

Feature	Juvederm (HA)	Radiesse (CaHA)	Sculptra (PLLA)
Material	Hyaluronic acid gel	Calcium hydroxylapatite microspheres in gel	Poly-L-lactic acid microparticles
Mechanism	Adds volume directly	Adds volume + stimulates collagen	Stimulates collagen production (gradual volume)
Results onset	Immediate	Immediate + progressive	Gradual (2-6 months)
Duration	6-18 months	12-18 months	Up to 2+ years
Reversible	Yes (hyaluronidase)	No	No
Manufacturer	Allergan (AbbVie)	Merz Aesthetics	Galderma

Juvederm: The Versatile Standard

Juvederm is the world’s most popular dermal filler brand. It is a hyaluronic acid (HA) gel that comes in multiple formulations, each designed for specific treatment areas and purposes:

• Juvederm Voluma — high-density gel for cheek augmentation and mid-face volume
• Juvederm Volux — strongest formulation for chin and jawline contouring
• Juvederm Volbella — soft gel for lips and fine periorbital lines
• Juvederm Volift — medium density for nasolabial folds and general facial contouring

Best for:

• Lip augmentation
• Nasolabial fold correction
• Under-eye hollow treatment
• Chin and jawline definition
• First-time filler patients (reversible = safety net)

Limitations:

• Shorter duration than Radiesse or Sculptra
• May require repeat treatments every 6-12 months
• Higher product cost per session for large-volume treatments

Learn more about Juvederm treatments on our Juvederm treatment page.

Radiesse: Volume Plus Collagen Stimulation

Radiesse uses calcium hydroxylapatite (CaHA) microspheres suspended in a water-based gel. This gives it a unique dual mechanism: the gel provides immediate volume, while the CaHA microspheres act as a scaffold that stimulates your body to produce new collagen over time.

Best for:

• Cheek and mid-face volumization
• Jawline contouring
• Nasolabial folds
• Marionette lines
• Hand rejuvenation (Radiesse is FDA-approved for hands)
• Patients who want both immediate and progressive results

Limitations:

• Not suitable for lips (too firm) or under-eye area
• Not reversible — if you dislike the result, you must wait for it to be absorbed
• White color of microspheres means it is not ideal for very thin skin areas where it might be visible

Sculptra: The Long Game

Sculptra is fundamentally different from Juvederm and Radiesse. It is not really a “filler” in the traditional sense — it is a biostimulator. Poly-L-lactic acid (PLLA) microparticles are injected into the deep dermis, where they trigger a gradual inflammatory response that results in new collagen formation over 2-6 months.

Best for:

• Overall facial volume restoration (especially temple, cheek, jawline hollowing)
• Patients who prefer gradual, natural-looking improvement
• Long-term rejuvenation (results can last 2+ years)
• Patients willing to wait for results and invest in multiple sessions

Limitations:

• No immediate visible result — the initial volume from the water carrier fades within days
• Requires 2-3 sessions spaced 4-6 weeks apart for optimal results
• Risk of granulomas (nodules) if injected improperly
• Not suitable for lips, under-eyes, or precise targeted augmentation
• Not reversible

Explore our Sculptra treatment options for more details.

Head-to-Head: Which Should You Choose?

Scenario 1: “I want fuller lips”

Winner: Juvederm (Volbella or Volift). It is the only option among these three that is safe and effective for lip augmentation. Radiesse and Sculptra are not suitable for lips.

Scenario 2: “My cheeks look hollow and aged”

For immediate result: Juvederm Voluma or Radiesse. For gradual, long-lasting result: Sculptra. Many experienced injectors at RE:BERRY combine Sculptra for the deep structural foundation with Juvederm for surface-level refinement.

Scenario 3: “I have deep nasolabial folds”

Winner: Juvederm Volift or Radiesse. Both provide immediate correction. Radiesse offers additional collagen stimulation for longer-lasting results.

Scenario 4: “I want overall facial rejuvenation”

Winner: Sculptra. For patients who want comprehensive rejuvenation across the entire face rather than targeted correction of one area, Sculptra’s collagen-stimulating approach provides the most natural, widespread improvement.

Scenario 5: “I am getting fillers for the first time”

Winner: Juvederm. It is reversible, provides immediate results (so you can see if you like it), and is the most well-studied filler on the market.

Combining Fillers for Optimal Results

Experienced injectors rarely use just one filler. At RE:BERRY Myeongdong, Dr. Baek Seung-Jae frequently designs multi-product treatment plans. A common combination includes Sculptra for deep structural support, Juvederm for precise contour refinement, and a Belotero product for delicate areas like the under-eye or lips.

The combination approach achieves results that no single filler can match — immediate visible improvement (from HA fillers) with progressive, long-lasting rejuvenation (from biostimulators).

Pricing at RE:BERRY Myeongdong (April 2026)

Treatment	Price
Imported Filler 1cc (Juvederm, cheek area)	₩359,000 (first visit)
Juvederm Lip Filler 1cc + Mouth Corner Botox	₩460,000
Radiesse 1 Syringe + Belotero Soft 1cc + Juvelook Dermashine 5cc	₩1,560,000

All prices exclude 10% VAT. April 2026 promotional pricing.

Frequently Asked Questions

Can I get Sculptra and Juvederm in the same session?

Yes, though typically in different areas. Sculptra is placed in the deep tissues of the cheeks and temples, while Juvederm refines superficial contours in the lips, nasolabial folds, or chin.

Which filler hurts the most?

Most modern fillers include lidocaine (a local anesthetic) in the gel, so pain is minimal. Sculptra may cause slightly more discomfort as it is injected deeper and in larger volumes. We apply numbing cream before all filler treatments.

What if I do not like the result?

If you received Juvederm (HA filler), it can be dissolved with hyaluronidase within minutes. For Radiesse and Sculptra, the results are not reversible and must be waited out. This is why we recommend Juvederm for first-time patients.