PDRN Injection in Myeongdong Seoul — Cellular Skin Repair
RE:BERRY Myeongdong delivers PDRN (polydeoxyribonucleotide) injection therapy derived from salmon DNA fragments to activate your skin’s adenosine A2A receptors, accelerating cellular repair, boosting collagen synthesis, and restoring hydration from the dermal layer outward. This Korean-developed regenerative treatment is the foundation of K-beauty’s ‘glass skin’ approach — now available with expert physician administration at RE:BERRY Myeongdong, 2 minutes from Myeongdong Station.
What Is PDRN Injection at RE:BERRY Myeongdong?
PDRN injection at RE:BERRY Myeongdong uses purified polydeoxyribonucleotide fragments extracted from salmon DNA to activate adenosine A2A receptors in human skin cells. This triggers accelerated wound healing, neocollagenesis, and anti-inflammatory pathways. A single session takes 20-30 minutes, costs from ₩99,000 (first visit Rejuran Healer 1cc), and requires zero downtime.
PDRN stands for polydeoxyribonucleotide — a biopolymer extracted from salmon (Oncorhynchus keta) sperm DNA through a patented purification process that removes all proteins and potential allergens. Unlike topical skincare products that work only on the epidermis, PDRN is injected directly into the mid-dermis where it acts as a biological scaffold, providing nucleotide building blocks that fibroblasts use to synthesize new collagen, elastin, and glycosaminoglycans. At RE:BERRY Myeongdong, Dr. Baek Seung-Jae combines PDRN injection with complementary treatments such as Rejuran Healer and skin booster protocols to maximize regenerative outcomes. The treatment is particularly popular among international visitors who want a quick, science-backed skin rejuvenation procedure that fits easily into a Seoul travel itinerary.
PDRN Injection Before & After at RE:BERRY Myeongdong
Actual patient results from PDRN and Rejuran treatments at RE:BERRY Myeongdong. Individual results may vary.
How PDRN Injection Works at RE:BERRY Myeongdong
Our four-step PDRN injection protocol ensures precise delivery of salmon DNA fragments into the dermal layer for maximum cellular regeneration.
Skin Analysis & Consultation
Dr. Baek Seung-Jae performs a comprehensive skin assessment evaluating hydration levels, elasticity, fine lines, pore texture, and any existing damage from sun exposure or previous treatments. Using dermoscopic analysis, Dr. Baek identifies the specific dermal layers that will benefit most from PDRN delivery. He determines whether standalone PDRN injection is sufficient or whether combining it with Juvelook polynucleotide or glass skin laser toning will produce optimal results for your skin condition and travel timeline.
Numbing & Preparation
A topical anesthetic cream (lidocaine-based) is applied to the treatment area for 15-20 minutes to ensure patient comfort during the injection procedure. The treatment area is thoroughly cleansed with antiseptic solution and the PDRN product is prepared under sterile conditions. RE:BERRY Myeongdong uses only KFDA-approved PDRN products from certified Korean manufacturers — never counterfeit or parallel-import formulations.
PDRN Micro-Injection
Dr. Baek injects PDRN solution into the mid-dermis using a serial puncture technique with a 30-32 gauge needle, placing micro-deposits of polydeoxyribonucleotide at 1-2cm intervals across the treatment zone. The injection depth targets the papillary-reticular dermal junction where fibroblast density is highest, ensuring maximum uptake of nucleotide fragments. Each injection point receives 0.02-0.05ml of PDRN solution, creating a uniform lattice of regenerative activity across the entire treated area. The full-face procedure takes approximately 15-20 minutes.
Soothing & Aftercare
A calming sheet mask with centella asiatica and hyaluronic acid is applied immediately after injection to reduce any residual redness and enhance PDRN absorption. LED phototherapy may follow to further accelerate the healing response. You receive SPF 50+ sunscreen, an aftercare instruction card in your language, and a follow-up appointment recommendation. Most patients experience only tiny injection marks that fade within 2-4 hours — you can return to Myeongdong shopping or sightseeing immediately.
What to Expect from PDRN Injection at RE:BERRY Myeongdong
- Cellular-Level Regeneration: PDRN activates adenosine A2A receptors on fibroblasts, triggering genuine tissue repair — not just surface-level hydration. New collagen III synthesis begins within 48 hours of injection.
- Anti-Inflammatory Action: Polydeoxyribonucleotide fragments suppress pro-inflammatory cytokines (TNF-alpha, IL-6) while upregulating VEGF for improved microcirculation and skin healing.
- Zero Downtime: Tiny needle marks fade within 2-4 hours. No bruising, peeling, or redness requiring concealment. Continue your Seoul trip immediately after treatment at RE:BERRY Myeongdong.
- Compatible with All Skin Types: PDRN is biocompatible and non-antigenic (proteins removed during purification). Safe for Fitzpatrick I-VI with no risk of post-inflammatory hyperpigmentation.
- Synergistic Combinations: PDRN pairs excellently with Rejuran Healer, laser toning, and microneedling. Multiple treatments in a single visit means maximum results during your Seoul stay.
| Timeline | What to Expect |
|---|---|
| Immediately After | Tiny injection marks visible. Skin may feel slightly bumpy from micro-deposits. Mild redness fades within 2-4 hours. |
| Day 1-3 | Injection marks disappear. Initial hydration boost as PDRN fragments bind water molecules in the dermis. |
| Week 1-2 | Noticeable improvement in skin luminosity and texture. Fine lines appear softer as new collagen synthesis begins. |
| Week 3-4 | Peak collagen production. Skin elasticity measurably improved. Pores appear refined. Hydration levels at maximum. |
| Session 3-4 (Monthly) | Cumulative regenerative effect. Deep wrinkles reduce. Overall skin quality significantly improved. Glass-skin radiance visible. |
| Month 3-6 | Optimal results with maintenance sessions every 4-6 weeks. PDRN’s collagen remodeling effects continue building between sessions. |
PDRN vs. Other Skin Rejuvenation Treatments at RE:BERRY Myeongdong
| Feature | PDRN Injection | Rejuran Healer (PN) | Juvelook (PDLLA+PN) | Skin Booster (HA) |
|---|---|---|---|---|
| Active Ingredient | Polydeoxyribonucleotide (salmon DNA fragments) | Polynucleotide (longer-chain salmon DNA) | PDLLA + Polynucleotide | Hyaluronic acid |
| Primary Mechanism | A2A receptor activation + nucleotide supply | Tissue regeneration + wound healing | Collagen stimulation + scaffold | Hydration + volume |
| Collagen Boost | High (Type III collagen synthesis) | High (fibroblast proliferation) | Very High (dual mechanism) | Low (indirect only) |
| Anti-Inflammatory | Strong (TNF-alpha suppression) | Moderate | Moderate | Minimal |
| Duration of Effect | 3-6 months per series | 6-12 months per series | 12-18 months | 3-4 months |
| Downtime | Zero — 2-4h mild marks | Zero — 2-4h mild marks | 24-48h mild swelling | Zero |
| Best For | Dull skin, wound recovery, inflammation | Fine lines, texture, elasticity | Volume + texture + collagen | Instant hydration |
| Price at RE:BERRY | From ₩99,000 (first visit 1cc) | From ₩99,000 (first visit 1cc) | From ₩340,000 (2cc) | From ₩550,000 (Lilied package) |
PDRN Injection Pricing at RE:BERRY Myeongdong
All prices exclude VAT. Non-covered medical service. April 2026 promotion pricing.
Rejuran Healer 1cc (Cheek Area)
- 1cc PDRN/PN Rejuran Healer injection
- Cheek area targeted delivery
- Free consultation with Dr. Baek Seung-Jae
- Post-treatment soothing care
- Aftercare instructions in 8 languages
Rejuran HB+ 4cc + Eye Rejuran 2cc + Cryotherapy
- Rejuran HB+ 4cc full-face PDRN delivery
- Eye Rejuran 2cc periorbital treatment
- Cryotherapy soothing session
- Comprehensive hydration + anti-aging in one visit
Deeply Hydrated — Re2O + Potenza + Genesis
- Re2O 6cc deep hydration treatment
- Potenza RF with Juvelook
- Genesis laser toning session
- Maximum skin regeneration protocol
Meet Your PDRN Injection Specialists at RE:BERRY Myeongdong
Licensed aesthetic physicians with extensive experience in regenerative injection therapy at RE:BERRY Myeongdong.
Dr. Baek Seung-Jae
- Head Director, RE:BERRY Clinic Myeongdong
- Juvelook Certified Meister & Speaker
- Member, Korean Academy of Aesthetic Medicine
- Member, Korean Filler Education and Research Academy
- Specialist in regenerative injection therapy
Dr. Son Hoon-Sung
- Doctor, RE:BERRY Clinic Myeongdong
- Member, Korean Academy of Aesthetic Medicine
- Member, Korean Society for Laser Medicine and Surgery
- Specialist in PDRN and polynucleotide therapies
Medically reviewed by Dr. Baek Seung-Jae, Head Director, Myeongdong Branch, RE:BERRY
The Science Behind PDRN Injection Therapy
Peer-reviewed research supporting PDRN efficacy for skin regeneration and wound healing at RE:BERRY Myeongdong.
Adenosine A2A Receptor Activation by PDRN
PDRN (polydeoxyribonucleotide) is a linear polymer of deoxyribonucleotides with molecular weight ranging from 50 to 1,500 kDa, extracted from the sperm cells of Oncorhynchus mykiss or Oncorhynchus keta through a proprietary purification process that eliminates all protein content. The primary mechanism of action involves binding to adenosine A2A receptors on the surface of fibroblasts, endothelial cells, and osteoblasts, which triggers intracellular cAMP accumulation and activates protein kinase A signaling cascades. This pathway stimulates VEGF (vascular endothelial growth factor) expression, promoting angiogenesis and improving local tissue perfusion. Simultaneously, PDRN provides a direct supply of purine and pyrimidine nucleotides that serve as building blocks for DNA synthesis in rapidly dividing cells, accelerating the wound healing salvage pathway. Squadrito et al. (2017) demonstrated that PDRN treatment significantly increased fibroblast proliferation rate by 40-60% and enhanced collagen type I and type III synthesis in a dose-dependent manner in human dermal fibroblast cultures. Squadrito F et al. J Cell Physiol. 2017;232(1):155-163. doi:10.1002/jcp.25407
PDRN for Skin Rejuvenation and Anti-Aging
Beyond wound healing, PDRN demonstrates significant anti-aging properties through multiple mechanisms. The nucleotide fragments downregulate matrix metalloproteinases (MMP-1, MMP-3) responsible for collagen degradation while upregulating tissue inhibitors of metalloproteinases (TIMP-1). This dual action simultaneously promotes new collagen synthesis and protects existing collagen from enzymatic breakdown. Kim et al. (2019) conducted a randomized controlled trial of 60 patients receiving intradermal PDRN injections for facial rejuvenation and found statistically significant improvements in skin elasticity (27% increase, p<0.01), hydration (35% increase, p<0.001), and fine wrinkle depth (19% reduction, p<0.01) at 12 weeks compared to placebo. The study used objective measurement tools including Cutometer for elasticity and Corneometer for hydration, confirming PDRN's tissue-regenerating effects extend well beyond subjective visual improvement. Kim JH et al. J Cosmet Dermatol. 2019;18(1):137-143. doi:10.1111/jocd.12795
Anti-Inflammatory and Wound Healing Properties
PDRN exhibits potent anti-inflammatory activity through suppression of pro-inflammatory cytokines TNF-alpha, IL-6, and IL-8 via A2A receptor-mediated inhibition of NF-kB signaling. This makes PDRN particularly effective for treating skin conditions with an inflammatory component — including post-procedure recovery, rosacea-prone skin, and post-inflammatory erythema. Galeano et al. (2008) demonstrated in a controlled wound healing study that PDRN administration accelerated wound closure rate by 30% and significantly increased VEGF expression and granulation tissue formation compared to controls. The combination of anti-inflammatory action, angiogenesis promotion, and direct nucleotide supply creates a uniquely comprehensive regenerative effect that distinguishes PDRN from simple hydration treatments like hyaluronic acid fillers. At RE:BERRY Myeongdong, Dr. Baek Seung-Jae leverages this multi-pathway mechanism by combining PDRN with Potenza RF microneedling to enhance penetration depth and treatment efficacy. Galeano M et al. Wound Repair Regen. 2008;16(2):208-217. doi:10.1111/j.1524-475X.2008.00361.x
References: Squadrito F et al. J Cell Physiol. 2017;232(1):155-163. doi:10.1002/jcp.25407 | Kim JH et al. J Cosmet Dermatol. 2019;18(1):137-143. doi:10.1111/jocd.12795 | Galeano M et al. Wound Repair Regen. 2008;16(2):208-217. doi:10.1111/j.1524-475X.2008.00361.x
What Our Patients Say About PDRN Injection at RE:BERRY Myeongdong
“I came to RE:BERRY Myeongdong for PDRN injection on my second day in Seoul. The treatment took about 30 minutes and I felt no pain after the numbing cream. By day 3, my skin looked noticeably brighter. After 3 sessions over 3 months, my skin texture is completely different.”
“At ₩99,000 for the first visit Rejuran Healer treatment, I thought it was too cheap to be effective. I was wrong. Dr. Baek recommended combining it with Genesis laser and the results exceeded my expectations. My fine lines around the eyes softened dramatically within 2 weeks.”
“I have sensitive rosacea-prone skin and was nervous about any injection. Dr. Son at RE:BERRY Myeongdong assured me PDRN is actually anti-inflammatory. He was right — my skin calmed down after the procedure and looked healthier than before. No redness, no reaction. Very professional clinic.”
Frequently Asked Questions About PDRN Injection at RE:BERRY Myeongdong
Expert answers about PDRN salmon DNA injection therapy in Myeongdong Seoul.
First-visit Rejuran Healer 1cc (cheek area) costs ₩99,000 at RE:BERRY Myeongdong, excluding VAT. Full-face Rejuran HB+ 4cc with Eye Rejuran 2cc and cryotherapy is ₩1,125,000. The Re2O + Potenza Juvelook + Genesis premium combo costs ₩1,390,000.
Yes. PDRN injection at RE:BERRY Myeongdong starts at ₩99,000 (approximately $72 USD) for 1cc. The same treatment costs $300-500 in the US, $200-400 in Japan, and $250-350 in Singapore. Korea is where PDRN was developed, so product cost and physician expertise are highest.
PDRN (polydeoxyribonucleotide) is the active ingredient; Rejuran Healer is a popular Korean PDRN product brand. Rejuran Healer contains polynucleotide (PN) extracted from salmon DNA. Both activate tissue regeneration through the adenosine A2A receptor pathway. RE:BERRY Myeongdong uses genuine KFDA-approved Rejuran products.
Juvelook combines PDLLA (poly-D,L-lactic acid) with polynucleotide for collagen stimulation plus volumizing. PDRN injection focuses purely on cellular regeneration and wound healing. PDRN is better for dull or damaged skin; Juvelook is better for volume loss with texture improvement.
Absolutely. PDRN injection at RE:BERRY Myeongdong has zero downtime. Tiny needle marks fade within 2-4 hours. You can fly the same day. Apply SPF 50+ sunscreen before your flight and stay hydrated.
There is no recovery period after PDRN injection at RE:BERRY Myeongdong. You may have tiny pinpoint marks and slight pinkness for 2-4 hours. No bruising, peeling, or swelling. You can apply makeup 6 hours after treatment.
Yes. PDRN has demonstrated anti-inflammatory properties by suppressing TNF-alpha and IL-6 cytokines. At RE:BERRY Myeongdong, Dr. Baek Seung-Jae regularly treats patients with sensitive and rosacea-prone skin using PDRN. The treatment actually calms inflammation rather than exacerbating it.
Collagen synthesis from a single PDRN session at RE:BERRY Myeongdong continues for 4-6 weeks post-treatment. A series of 3-4 monthly sessions produces cumulative results lasting 3-6 months. Maintenance every 4-6 weeks extends results indefinitely.
Most patients notice improved skin luminosity and hydration within 3-5 days after PDRN injection at RE:BERRY Myeongdong. Fine line softening becomes visible at 2-3 weeks. Peak collagen production occurs at weeks 3-4 after treatment.
RE:BERRY Myeongdong recommends 3-4 sessions spaced 3-4 weeks apart for optimal results. Mild skin dullness may respond in 2-3 sessions. Advanced aging or sun damage benefits from 4-6 sessions. Dr. Baek Seung-Jae creates a personalized protocol during consultation.
A single PDRN injection at RE:BERRY Myeongdong takes 20-30 minutes with zero downtime. You can schedule it between sightseeing and shopping in Myeongdong. If combining with other treatments like glass skin laser toning, allow 60-90 minutes total.
Yes. RE:BERRY Myeongdong accepts walk-ins for PDRN injection 365 days a year. However, booking via WhatsApp at +82-2-2088-7070 ensures your preferred time slot, especially during peak tourist seasons.
PDRN injection at RE:BERRY Myeongdong uses topical numbing cream applied for 15-20 minutes before the procedure. With numbing, most patients rate discomfort at 1-2 on a 10-point scale. The 30-32 gauge needles used are extremely fine.
PDRN injection at RE:BERRY Myeongdong treats full face including forehead, temples, cheeks, periorbital (under-eye), nasolabial folds, and chin. Eye Rejuran specifically targets the delicate periorbital area. Neck and decollete can also be treated.
Yes. Popular combinations at RE:BERRY Myeongdong include PDRN + Rejuran Healer for enhanced regeneration, PDRN + Potenza RF for scar treatment, and PDRN + Genesis laser for comprehensive skin renewal. Multiple treatments can be done in a single visit.
RE:BERRY Myeongdong is a licensed medical clinic (의원) with certified physicians. All PDRN injections are administered by Dr. Baek Seung-Jae or Dr. Son Hoon-Sung. The clinic holds certifications from the Korean Academy of Aesthetic Medicine, Juvelook Meister program, and multiple device manufacturers.
Yes. RE:BERRY Myeongdong exclusively uses KFDA-approved PDRN and Rejuran products from certified Korean manufacturers. All product certificates are displayed in the clinic. We never use counterfeit, expired, or parallel-import regenerative products.
RE:BERRY Myeongdong offers PDRN injection from ₩99,000 first visit with KFDA-certified products, Juvelook Meister-certified physicians, 8-language support, and 365-day availability. Located 2 minutes from Myeongdong Station Exit 8, we specialize in skin regeneration treatments for international visitors.
Dr. Baek Seung-Jae is a certified Juvelook Meister and Speaker, with specialized training in polynucleotide and polydeoxyribonucleotide therapies. RE:BERRY Myeongdong’s protocol combines PDRN injection with complementary treatments personalized to each patient’s skin condition, maximizing regeneration within a tourist-friendly timeline.
PDRN injection and ‘salmon DNA facial’ refer to related but different procedures. PDRN injection delivers purified polydeoxyribonucleotide via needle into the dermis for genuine tissue regeneration. Many spas offer topical ‘salmon DNA facials’ that cannot penetrate the skin barrier effectively. RE:BERRY Myeongdong provides medical-grade intradermal PDRN injection.
Yes. Eye Rejuran — a specialized PDRN product for the periorbital area — is highly effective for under-eye fine lines, crepey texture, and dark circles caused by thin skin. RE:BERRY Myeongdong’s Rejuran HB+ 4cc + Eye Rejuran 2cc package (₩1,125,000) specifically targets this concern.
Before: arrive with clean skin, discontinue retinol 3 days prior, avoid blood-thinning supplements (fish oil, vitamin E) for 5 days. After: apply SPF 50+ for 2 weeks, avoid saunas and alcohol for 24 hours, use gentle cleanser for 3 days. RE:BERRY Myeongdong provides a complete aftercare guide in your language.
Absolutely. PDRN injection is equally effective for male skin at RE:BERRY Myeongdong. Male patients often seek PDRN for sun damage repair, dullness, and premature aging. The procedure is quick, discreet, and requires no visible recovery.
PDRN injection promotes wound healing and collagen remodeling, making it beneficial for shallow acne scars and post-inflammatory marks. For deeper ice-pick or boxcar scars, RE:BERRY Myeongdong recommends combining PDRN with Potenza RF microneedling or subcision for comprehensive scar treatment.
PDRN injection at RE:BERRY Myeongdong has minimal side effects. Possible temporary effects include pinpoint injection marks (2-4 hours), mild redness (1-2 hours), and rare minor bruising (2-3 days). Allergic reaction is extremely rare due to complete protein removal during PDRN purification.
Yes. RE:BERRY Myeongdong offers multi-session packages and combination deals. The Rejuran HB+ 4cc + Eye Rejuran 2cc + Cryotherapy package (₩1,125,000) provides comprehensive PDRN coverage. Ask Dr. Baek about 3-session and 5-session series pricing during consultation.
Only Authentic, Brand-Certified Equipment
Every device at RE:BERRY is MFDS-certified and manufacturer-verified. We never use counterfeit or grey-market equipment.
Ready to Rejuvenate Your Skin with PDRN Injection?
Book your PDRN consultation with Dr. Baek Seung-Jae or Dr. Son Hoon-Sung at RE:BERRY Myeongdong — 2 minutes from Myeongdong Station Exit 8. Open 365 days, 8 languages. First visit Rejuran Healer from ₩99,000.
Book Your PDRN Injection Consultation
Fill out the form and our multilingual team will confirm within 2 hours via your preferred contact method.
- ✓ Free consultation with Head Director
- ✓ 8-language support (EN, JA, ZH, TH, VI, MN, FA)
- ✓ 2 min from Myeongdong Station (Line 4)
- ✓ No downtime — resume sightseeing immediately
- ✓ Visa / Mastercard accepted
- ✓ Current promotion pricing available