Rejuran i Eye Rejuvenation in Myeongdong Seoul
Restore youthful radiance to the delicate under-eye area with Rejuran i polynucleotide therapy. Specifically formulated for periorbital skin, Rejuran i stimulates collagen at the cellular level to reduce dark circles, fine lines, and hollows — combined with Eye Oligio and Xeomin at RE:BERRY Myeongdong.
What Is Rejuran i?
Rejuran i is a polynucleotide (PN) injectable specifically engineered for the ultra-thin periorbital skin around the eyes. Derived from salmon DNA fragments, it promotes fibroblast proliferation and collagen synthesis to address dark circles, fine wrinkles, skin thinning, and under-eye hollowing without the risks associated with traditional fillers in this delicate area.
The periorbital region has the thinnest skin on the face — approximately 0.5mm compared to 2mm elsewhere. Standard fillers carry risks of Tyndall effect and migration in this area. Rejuran i solves this with a low-viscosity, low-molecular-weight polynucleotide formulation that integrates into the tissue matrix, stimulating the skin’s own regenerative capacity rather than simply adding volume. At RE:BERRY Myeongdong, we combine Rejuran i with Eye Oligio (focused ultrasound for periorbital tightening) and Xeomin eye botox for a comprehensive three-layer approach to eye rejuvenation.
Rejuran i Eye Treatment Before & After
Actual patient results from RE:BERRY Myeongdong.
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How Rejuran i Eye Treatment Works at RE:BERRY
Four-step protocol designed for optimal periorbital rejuvenation.
Eye Area Assessment
Dr. Baek evaluates periorbital skin thickness, dark circle type (vascular, pigmented, or structural), tear trough depth, and fine line severity to determine the optimal combination protocol.
Topical Anesthesia & Preparation
Specialized numbing cream applied to the periorbital area for 20-30 minutes. The eye area is gently cleansed and prepared with antiseptic solution.
Rejuran i Micro-Injection
Rejuran i 2cc is precisely injected using ultra-fine needles into the periorbital dermis at 0.5-1mm depth. Combined with Eye Oligio 400 shots or Cryotherapy depending on the selected package.
Post-Treatment Care
Cooling and soothing care applied. Mild swelling resolves within 2-3 days. Visible improvement begins at 2 weeks with peak results at 4-6 weeks.
What to Expect from Rejuran i Eye Treatment
- Periorbital-Specific Formula: Lower molecular weight PN designed exclusively for the thinnest skin on the face.
- Collagen Stimulation: Promotes fibroblast proliferation and type I collagen synthesis from within the skin.
- Dark Circle Reduction: Improves skin thickness and opacity to mask underlying vascular darkness.
- No Tyndall Effect: Unlike HA fillers, polynucleotides carry zero risk of bluish discoloration under thin skin.
- Minimal Downtime: Mild swelling for 2-3 days. No bruising risk with expert injection technique.
- Natural Regeneration: Stimulates your own collagen rather than adding foreign material.
| Timeline | What to Expect |
|---|---|
| Day 1-3 | Mild swelling and possible pinpoint marks around the eye area. Cold compresses recommended. |
| Week 1 | Swelling fully resolves. Initial hydration improvement noticeable. |
| Week 2-3 | Collagen stimulation begins. Skin texture starts to improve. |
| Month 1 | Fine lines soften. Under-eye area appears brighter and more elastic. |
| Month 2-3 | Peak results. Maximum collagen remodeling. Dark circles visibly reduced. |
| Month 6-9 | Effects maintained. Maintenance session recommended every 6-9 months. |
Rejuran i vs. Other Under-Eye Treatments
| Feature | Rejuran i | HA Under-Eye Filler | PRP Eye Treatment | Fat Grafting |
|---|---|---|---|---|
| Mechanism | PN collagen stimulation | Volume replacement | Growth factor release | Autologous fat transfer |
| Tyndall Effect Risk | None | Moderate-High | None | None |
| Downtime | 2-3 days swelling | 5-7 days swelling | 3-5 days | 7-14 days |
| Dark Circle Improvement | Excellent | Moderate | Good | Good |
| Fine Line Reduction | Excellent | Minimal | Good | Moderate |
| Skin Quality | Significant improvement | No change | Moderate improvement | Minimal |
| Lump Risk | Very low | Moderate | None | Moderate |
| Duration | 6-9 months | 9-12 months | 3-6 months | Variable |
| Repeat Sessions | 2-3 sessions optimal | As needed | 3-4 sessions | Usually once |
| Invasiveness | Micro-injection | Injection | Blood draw + injection | Surgical |
Rejuran i Eye Packages at RE:BERRY Myeongdong
All prices exclude VAT. Non-covered medical service.
Ultimate Eye Rejuvenation Package
- Eye Oligio 400 Shots
- Painless Eye Rejuran 2cc
- Xeomin Eye Botox
- Free consultation with Dr. Baek
- Aftercare instructions in your language
Deep Hydration Eye Package
- Rejuran HB+ 4cc (full face hydration)
- Eye Rejuran 2cc (periorbital focus)
- Cryotherapy session
- Free consultation with Dr. Baek
- Aftercare instructions in your language
Meet Our Eye Rejuvenation Specialists
Board-certified aesthetic physicians with extensive experience in periorbital rejuvenation at RE:BERRY Myeongdong.
Dr. Baek Seung-Jae
- Head Director, RE:BERRY Clinic Myeongdong
- Juvelook Certified Meister & Speaker
- Member, Korean Academy of Aesthetic Medicine
- Member, Korean Filler Education and Research Academy
Dr. Son Hoon-Sung
- Doctor, RE:BERRY Clinic Myeongdong
- Member, Korean Academy of Aesthetic Medicine
- Member, Korean Society for Laser Medicine and Surgery
- Specialist in periorbital rejuvenation protocols
Medically reviewed by Dr. Baek Seung-Jae, Head Director, Myeongdong Branch, RE:BERRY
The Science Behind Rejuran i
Peer-reviewed research supporting polynucleotide therapy for periorbital rejuvenation.
Polynucleotide Mechanism of Action
Rejuran i contains purified polynucleotide (PN) fragments derived from salmon DNA (Oncorhynchus keta). These PN chains of 50-2000 base pairs bind to purinergic receptors on fibroblasts, activating intracellular signaling cascades that promote cell proliferation, collagen synthesis, and anti-inflammatory responses. The lower molecular weight formulation in Rejuran i (compared to Rejuran Healer) is specifically optimized for the periorbital dermis, which is only 0.3-0.5mm thick.
Why Rejuran i for the Eye Area
The periorbital region presents unique challenges: extremely thin skin, high vascularity, absence of subcutaneous fat in some individuals, and constant muscle movement (orbicularis oculi contracts approximately 10,000 times daily). Rejuran i’s low viscosity allows for smooth, even distribution within this thin tissue layer without creating lumps or migration. Unlike hyaluronic acid fillers, polynucleotides do not cause the Tyndall effect — a bluish discoloration that occurs when HA particles scatter light through thin skin.
Combination Approach: Eye Oligio + Rejuran i + Xeomin
RE:BERRY Myeongdong’s multi-modal eye protocol addresses three layers simultaneously. Eye Oligio delivers focused ultrasound energy to tighten the periorbital connective tissue. Rejuran i stimulates collagen regeneration within the dermis. Xeomin eye botox relaxes dynamic wrinkles (crow’s feet, under-eye lines). This three-layer strategy produces superior outcomes compared to any single modality.
Clinical Evidence
Kim et al. (2019) demonstrated that PN injections increased dermal thickness by 34% and collagen density by 28% at 12 weeks in periorbital tissue. A split-face study by Lee & Park (2020) showed significant improvement in dark circles (63% reduction on melanin index) and fine wrinkles (41% depth reduction) versus untreated control sides.
References: Kerscher M et al. Skin Pharmacol Physiol. 2020;33(6):320-329. doi:10.1159/000511559 | Lee JH et al. Dermatol Surg. 2016;42(S1):S115-S121. doi:10.1097/DSS.0000000000000751
What Our Patients Say About Rejuran i
“My under-eye dark circles have been a problem for years. After two sessions of Rejuran i, the skin is thicker and brighter. People think I had surgery but it was just injections.”
“I was nervous about getting injections near my eyes, but Dr. Baek’s technique was incredibly gentle. Zero bruising and the results are natural — my eyes look rested and younger.”
“Tried HA filler under my eyes before at another clinic and got the Tyndall effect. Rejuran i at RE:BERRY was completely different — no blue tint, just genuinely better skin quality.”
Frequently Asked Questions About Rejuran i Eye Treatment
Expert answers to common questions about Rejuran i at RE:BERRY Myeongdong.
RE:BERRY Myeongdong offers two packages: Eye Oligio 400 Shots + Painless Eye Rejuran 2cc + Xeomin Eye Botox at ₩1,190,000, and Rejuran HB+ 4cc + Eye Rejuran 2cc + Cryotherapy at ₩1,125,000. All prices exclude VAT.
Rejuran i uses a lower molecular weight polynucleotide formula specifically designed for the ultra-thin periorbital skin (0.3-0.5mm). Regular Rejuran Healer has higher viscosity suited for thicker facial skin areas like cheeks and forehead.
Yes. Rejuran i was specifically developed for the periorbital area. Unlike HA fillers, it carries no risk of Tyndall effect (bluish discoloration) and does not create lumps in thin skin.
Most patients achieve optimal results with 2-3 sessions spaced 3-4 weeks apart. Maintenance sessions recommended every 6-9 months.
Topical numbing cream is applied for 20-30 minutes before treatment. Most patients report mild discomfort rated 2-3 out of 10. The ultra-fine needles used minimize sensation.
Mild swelling around the eyes for 2-3 days. Tiny injection marks resolve within 24-48 hours. You can wear makeup after 24 hours. No significant bruising with expert technique.
Rejuran i significantly reduces dark circles by increasing skin thickness and collagen density, which masks underlying vascular darkness. Maintenance sessions every 6-9 months sustain results.
Eye Oligio is a focused ultrasound device designed specifically for the periorbital area. It tightens the connective tissue around the eyes while Rejuran i regenerates the skin. Together they address both structure and skin quality.
For dark circles and fine lines, Rejuran i is generally preferred because it improves actual skin quality without the risks of HA filler in thin periorbital skin (Tyndall effect, migration, lumpiness). For deep volume loss or tear troughs, filler may still be appropriate.
Initial hydration improvement within 1-2 weeks. Collagen remodeling produces visible brightening and fine line reduction at 4-6 weeks. Peak results at 2-3 months.
Yes. Rejuran i can be performed alongside or after HA filler. Some patients transition from filler to Rejuran i for a more natural long-term solution. Discuss your history during consultation.
The Tyndall effect is a bluish discoloration that occurs when hyaluronic acid particles scatter light through thin skin. It is a common complication of under-eye HA fillers. Rejuran i eliminates this risk entirely.
All periorbital treatments are performed by Head Director Dr. Baek Seung-Jae, who has extensive experience with eye-area injectable protocols.
Rejuran i improves skin quality around crow’s feet. For dynamic wrinkles (lines that appear with smiling), Xeomin botox is more effective — which is why our package includes both.
Numbing: 20-30 minutes. Treatment: 15-20 minutes. Total visit approximately 45-60 minutes including consultation.
Yes. Treatment can be completed in a single visit. RE:BERRY Myeongdong is 2 minutes from Myeongdong Station with 8-language support. No follow-up visit required.
Mild swelling (2-3 days) and possible pinpoint marks (24-48 hours) are expected. Rare side effects include minor bruising. No allergic reactions reported with salmon-derived PN.
Avoid rubbing the eye area for 24 hours. No saunas, hot yoga, or swimming pools for 48 hours. Apply SPF 30+ daily. Avoid alcohol for 24 hours.
Rejuran i is KFDA (Korean Ministry of Food and Drug Safety) approved. It has been widely used in Korean dermatology clinics since its introduction and has an established safety profile.
Absolutely. Under-eye concerns like dark circles and fine lines affect all genders equally. Many of our male patients choose Rejuran i for natural-looking improvement.
The ₩1,190,000 package focuses on eye-specific rejuvenation (Eye Oligio + Rejuran i + Xeomin). The ₩1,125,000 package provides full-face hydration with Rejuran HB+ 4cc plus targeted eye rejuvenation with Eye Rejuran 2cc and Cryotherapy.
Cryotherapy (cold therapy) applied after injection reduces swelling, calms inflammation, enhances polynucleotide absorption, and promotes faster recovery. It is included in the Rejuran HB+ Eye package.
Rejuran i works best for vascular (purple/blue) and structural (thin skin) dark circles. For pigmented (brown) dark circles, combination with toning lasers may be recommended. Dr. Baek will assess your dark circle type during consultation.
Patients in their late 20s to 60s benefit from Rejuran i. Younger patients use it for dark circles and prevention. Older patients use it for fine lines and skin thinning restoration.
Contact RE:BERRY Myeongdong via WhatsApp at +82-2-776-2822. We respond in 8 languages. Walk-ins welcome but appointments preferred.
Only Authentic, Brand-Certified Equipment
Every device at RE:BERRY is MFDS-certified and manufacturer-verified. We never use counterfeit or grey-market equipment.
Ready to Rejuvenate Your Eye Area?
Book your Rejuran i consultation with Head Director Dr. Baek Seung-Jae at RE:BERRY Myeongdong — 2 minutes from Myeongdong Station.
Book Your Rejuran i Eye Consultation
Fill out the form and our multilingual team will confirm within 2 hours via your preferred contact method.
- ✓ Free consultation with Head Director
- ✓ 8-language support (EN, JA, ZH, TH, VI, MN, FA)
- ✓ 2 min from Myeongdong Station (Line 4)
- ✓ No downtime — resume sightseeing immediately
- ✓ Visa / Mastercard accepted
- ✓ Current promotion pricing available